Results 51 to 60 of about 303,596 (194)

Rituximab Treatment in a Patient with Active Graves’ Orbitopathy and Psoriasis

, 2017
Management of Graves’ orbitopathy remains an important therapeutic challenge. Current therapeutic modalities are unsatisfactory in about one third of patients.
Nur Kebapçı, Nilgün Yıldırım, Belgin Efe, Tülay Şimşek   +3 more
core   +1 more source

Serum selenium status in Graves' disease with and without orbitopathy: A case-control study [PDF]

, 2014
OBJECTIVE: Selenium is effective in improving quality of life and reducing the progression of active Graves' orbitopathy. The effect of correcting relative selenium deficiency on improving Graves' orbitopathy is unknown, as baseline selenium levels have ...
Khong, JJ, Goldstein, RF, Sanders, KM, Pope, J, Craig, JE, Ebeling, PR, Schneider, H, Burdon, KP   +7 more
core   +1 more source

Deep Cleaning Device as a Treatment Is Effective for Blepharitis and Significantly Reduces Bacterial Load

Journal of Ophthalmology, Volume 2026, Issue 1, 2026.
Objective To evaluate the efficacy and safety of the Deep Cleaning Device for the treatment of blepharitis. Methods This prospective, randomized controlled trial enrolled 51 adult patients with blepharitis, who were randomly allocated to two treatment groups.
Ya Wen, Jiayu Bao, Ao Li, Yubo Wu, Yang Zhang, Lei Tian, Ying Jie, Qinxiang Zheng   +7 more
wiley   +1 more source

PDGFRα+DPP4+ Fibroblasts‐Macrophage Crosstalk Induces Orbital Fibrosis in Treatment‐Resistant Thyroid Eye Disease via the GAS6‐AXL Pathway

Advanced Science, Volume 12, Issue 45, December 4, 2025.
This study elucidates macrophage‐induced orbital fibrosis in TED via the GAS6‐AXL pathway, a treatment‐resistant disorder lacking non‐surgical therapies. Using a novel patient cell‐derived orthotopic animal model of orbital fibrosis for TED, we repurpose an existing fibrosis therapy, addressing the absence of stable models and offering a potential ...
Lu Cheng, Jinwei Cheng, Guiling Liang, Xiaorui Wang, Yanwen Ge, Jiapei Liu, Luwei Cai, Hui Ying, Fenfen Wang, Jing Hu, Yufan Wang, Philipp E. Scherer, Ben Zhou, Mengle Shao, Fang Zhang   +14 more
wiley   +1 more source

Allosteric Modulators of Steroid Hormone Receptors : Structural Dynamics and Gene Regulation [PDF]

, 2012
Peer ...
McEwan, Iain J, Kumar, Raj
core   +1 more source

SOCIETY FOR ENDOCRINOLOGY ENDOCRINE EMERGENCY GUIDANCE: Acute management of the endocrine complications of checkpoint inhibitor therapy.

, 2022
Immunotherapy treatment with checkpoint inhibitors (CPI) (CTLA-4 and PD-1 inhibitors) significantly improves survival in a number of cancers. Treatment can be limited by immune-mediated adverse effects including endocrinopathies such as hypophysitis ...
Cooksley, T, Higham, CE, Society for Endocrinology Clinical Committee,, Olsson-Brown, A, Morganstein, D, Lorigan, P, Larkin, J, Trainer, PJ, Carroll, P   +8 more
core   +1 more source

Refractory Hypothyroidism: Unexpected Outcome During Treatment of Giant Cell Arteritis

Clinical Case Reports, Volume 13, Issue 10, October 2025.
Refractory hypothyroidism in a patient with giant cell arteritis: doses of levothyroxine and serum TSH levels during long term follow‐up. ABSTRACT Refractory hypothyroidism is not uncommon in patients treated with oral levothyroxine, and it represents a challenge for clinicians as regards a physiopathological diagnosis and the most appropriate long ...
Elise Deprince, Solange Grunenwald, Celine Mouly, Julie Benoit, Philippe J. Caron   +4 more
wiley   +1 more source

Ten Year Outcome of Anti‐Thyroid Drug Treatment for First Episode Graves' Thyrotoxicosis: The Predictive Importance of TRAb

Clinical Endocrinology, Volume 103, Issue 4, Page 612-618, October 2025.
ABSTRACT Objective To establish the risk and time course of recurrent thyrotoxicosis following withdrawal of anti‐thyroid drugs (ATD) and risk factors for recurrence. Design Single‐centre retrospective study. Methods Two hundred and ninety people with a first episode of Graves' thyrotoxicosis, who completed a course of ATD, were included.
Nyo Nyo Z. Tun, Nicola N. Zammitt, Mark W. J. Strachan, Jonathan R. Seckl, Fraser W. Gibb   +4 more
wiley   +1 more source

Thyroid Orbitopathy and Dry Eye

, 2011
Thyroid orbitopathy (TO) is an inflammatory autoimmune disease of the orbital and periorbital tissues that is characterized by the presence of autoantibodies against thyroid-stimulating hormone receptor (TSH-R).
Canan Gürdal, Özge Saraç
core   +1 more source

Expression of the neural cell adhesion NCAM in endocrine cells of the ovary [PDF]

, 1991
In the adult mammalian ovary morphogenesis and differentiation processes are under hormonal control and, thus, occur in a highly regulated way during the sexual cycle.
Lahr, G., Gratzl, Manfred, Mayerhofer, Artur   +2 more
core   +1 more source