Results 61 to 70 of about 303,596 (194)

Another pleiotropic effect of SGLT2 inhibitors: Is it a new frontier in thyroid function regulation?

Thyroid Research
In our review, we present possible hypotheses that might explain how sodium glucose cotransporter 2 (SGLT2) inhibitors affect thyroid function. We describe mutual interactions between thyroid hormones and the development of diabetes and obesity.
Michał Szklarz, Katarzyna Wołos-Kłosowicz, Joanna Szulc, Jan Górny, Robert Modzelewski, Wojciech Matuszewski   +5 more
doaj   +1 more source

Endocrine orbitopathy: the present view of a clinical endocrinologist [PDF]

Vnitřní lékařství, 2017
Graves orbitopathy (GO) occurs in 25-50 % cases of Graves disease. Only in 5 % of patients the eye threatening GO is present. About 5-10 % and 10 % cases are present in euthyroid and hypothyroid patients respectively. All patients with GO should be assessed for activity (clinical activity score - CAS) and severity of the disease. Basic preconditions of
openaire   +2 more sources

British Thyroid Association Survey of Graves' Disease Management in the UK

Clinical Endocrinology, Volume 103, Issue 3, Page 376-384, September 2025.
ABSTRACT Background Recent years have seen changes and uncertainties in evidence and guideline recommendations in Graves' disease treatment. To understand the impact of these developments on current practice, we undertook a survey of Graves' disease management in the United Kingdom and compared this to other national and international surveys.
Michael Atkinson, Medha Agrawal, Koteshwara Muralidhara, Prakash Abraham, Bijay Vaidya, Onyebuchi E. Okosieme   +5 more
wiley   +1 more source

Radiological Activity Score (RAS)—MRI Characteristics in Dysthyroid Optic Neuropathy in a Multi‐Ethnic Thyroid Eye Disease Population

Clinical Endocrinology, Volume 103, Issue 3, Page 385-395, September 2025.
ABSTRACT Purpose Dysthyroid Optic Neuropathy (DON) is a sight threatening and diagnostically challenging complication of Thyroid Eye Disease (TED). We provide a comparative analysis of the MRI features associated between patietnts with and without DON. Methods Anonymised retrospective cohort study of patients with TED over eleven years.
Malik Moledina, Vickie Lee, Kunwar Bhatia, Gitta Madani, Claire Feeney, Nicole George, Nour Houbby, Daisy Metcalf, Natalie Man, Rajni Jain, Ahmad Aziz, Ravi Kumar Lingam   +11 more
wiley   +1 more source

Age-dependent diagnostic and treatment response prediction of TBII and TSI in Graves’ orbitopathy: integration with orbital MRI biomarkers

Frontiers in Immunology
BackgroundThyrotropin-binding inhibitory immunoglobulin (TBII) is involved in the pathogenesis of Graves’ orbitopathy (GO). Although thyroid-stimulating immunoglobulin (TSI) may offer superior diagnostic or prognostic value, its utility remains ...
Cheng Song, Cheng Song, Xiao Wang, Xiao Wang, Xiao Wang, Qintao Ma, Qintao Ma, Genfeng Yu, Genfeng Yu, Yan Zhu, Yan Zhu, Zimeng Huang, Zimeng Huang, Tian Chen, Tian Chen, Kai Huang, Kai Huang, Yuanping Hai, Yuanping Hai, Yuanping Hai, Haixiong Chen, Haixiong Chen, Yongbo Duan, Jie Shen, Jie Shen, Jie Shen   +25 more
doaj   +1 more source

Autoimmune Diseases: Molecular Pathogenesis and Therapeutic Targets

MedComm, Volume 6, Issue 7, July 2025.
This review provides a comprehensive overview of common autoimmune diseases, details clinical manifestations and summarizes the pathogenesis, including the breakdown of immune tolerance, initiation of autoimmune responses, and their progressive amplification.
Xiaoshuang Song, Hantian Liang, Fang Nan, Wenjing Chen, Junyao Li, Liu He, Yiping Cun, Zhenhong Li, Wei Zhang, Dunfang Zhang   +9 more
wiley   +1 more source

Steroid Hormones and Endocrine Disruptors: Recent Advances in Receptor–Mediated Actions [PDF]

, 2001
It has been accepted that receptor-mediated action of steroid hormones depends on both the receptor and the hormonal level. The mechanism of transcription by steroid receptors is mediated by cofactors, which function as co-activators or co-repressors,
Indarto, Dono, Izawa, Masao
core  

Steroid Hormones and Endocrine Disruptors: Recent Advances in Receptor–Mediated Actions [PDF]

, 2017
It has been accepted that receptor-mediated action of steroid hormones depends on both the receptor and the hormonal level. The mechanism of transcription by steroid receptors is mediated by cofactors, which function as co-activators or co ...
Indarto, Dono, Izawa, Masao
core  

Mutations of the ret protooncogene in German multiple endocrine neoplasia families: Relation between genotype and phenotype. [PDF]

, 1996
It has been suggested that not only the position but also the nature of the mutations of the ret protooncogene strongly correlate with the clinical manifestation of the multiple endocrine neoplasm type 2 (MEN 2) syndrome.
Rendl, J., Frank-Raue, K., Höppner, W., Haase, R., Mann, K., Deckart, H. F., Ritter, M. M., Frilling, A., Scholz, G. H., Dralle, H., Kirchner, R., Kotzerke, J., Klempa, J., Hampel, R., Raue, F., Seif, F.   +15 more
core   +1 more source

Unlocking the Therapeutic Potential: Selenium and Myo-Inositol Supplementation in Thyroid Disorders—Efficacy and Future Directions

Life
Background/Objectives: Thyroid disorders such as Hashimoto’s thyroiditis and Graves’ disease represent major endocrine challenges worldwide, often requiring long-term management.
Chinnu George Samuel, Parul Singh, Hala Abdullahi, Ibrahim Ibrahim   +3 more
doaj   +1 more source