Results 61 to 70 of about 22,891,001 (363)
SchussenAktivplus: reduction of micropollutants and of potentially pathogenic bacteria for further water quality improvement of the river Schussen, a tributary of Lake Constance, Germany [PDF]
, 2013 The project focuses on the efficiency of combined technologies to reduce the release of micropollutants and bacteria into surface waters via sewage treatment plants of different size and via stormwater overflow basins of different types. As a model river
Amler, Klaus +35 more
core +1 more source
Primary hyperparathyroidism having multiple Brown tumors mimicking malignancy
Indian Journal of Endocrinology and Metabolism, 2012 Primary hyperparathyroidism is a disease characterized by excessive secretion of parathormone. During the course of this disease, bone loss occurs, particularly depending on resorption of the skeletal system.
Ekram Ullah +3 more
doaj +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Клиническая практика, 2018 The aim of this study was to identify the specifics of the endocrine system functioning in males professionally involved in sports. We have observed 70 sportsmen and 70 students of the Maritime Academy. The check-up included the following procedures: the
S. D. Megeryan
doaj +1 more source
Zearalenone endocrine system catch [PDF]
Zbornik Matice Srpske za Prirodne Nauke, 2005 This paper deals with the contamination of our environment with thousands of both natural and man-made chemicals which affect the endocrine system of humans and animals.
Bursić Vojislava P., Jurić Verica B.
doaj +1 more source
Сучасні медичні технології, 2023 Aim. The work aimed to study the nature of changes in endocrine signals (insulin and cortisol) and bioactive molecules that control inflammation and activation of process synthesis (interleukin-2 (IL-2), interleukin-8 (IL-8), vascular endothelial growth ...
S. B. Pavlov +5 more
doaj +1 more source
The unsolved case of “bone-impairing analgesics”. The endocrine effects of opioids on bone metabolism [PDF]
, 2015 The current literature describes the possible risks for bone fracture in chronic analgesics users. There are three main hypotheses that could explain the increased risk of fracture associated with central analgesics, such as opioids: 1) the increased ...
COLUZZI, FLAMINIA +3 more
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The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1
FEBS Letters, EarlyView.MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson +7 more
wiley +1 more source
FEBS Letters, EarlyView.In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker +8 more
wiley +1 more source
Silent Spring - the lost call [PDF]
, 2008 The "silence" in Rachel Carson's Silent Spring1 alludes to the demise of bird populations through reproductive problems and death resulting from exposure to the pesticides of that time, many of which are endocrine active.
Mary Ann Ottinger, Michael J. Quinn
core +1 more source