Results 71 to 80 of about 670,614 (335)

Endocrine system disturbances in children with inherited metabolic diseases: a narrative review

Frontiers in Endocrinology
Inborn metabolic diseases (IMDs) represent a diverse and complex group of rare disorders, typically resulting from variants in genes that encode specific enzymes or cofactors, leading to reduced or absent enzymatic activity.
Veronica Maria Tagi, Veronica Maria Tagi, Laura Fiori, Chiara Montanari, Chiara Montanari, Davide Tonduti, Davide Tonduti, Matilde Ferrario, Mirko Gambino, Ilenia Pia Greco, Alessandra Cecchini, Valeria Calcaterra, Valeria Calcaterra, Gianvincenzo Zuccotti, Gianvincenzo Zuccotti, Elvira Verduci, Elvira Verduci   +16 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Expression of the neural cell adhesion NCAM in endocrine cells of the ovary [PDF]

, 1991
In the adult mammalian ovary morphogenesis and differentiation processes are under hormonal control and, thus, occur in a highly regulated way during the sexual cycle.
Gratzl, Manfred, Lahr, G., Mayerhofer, Artur   +2 more
core   +1 more source

A professional development framework supporting life sciences educators' pedagogical content knowledge in the relationship between the human nervous system and the endocrine system [PDF]

, 2021
Nathasia Naidoo
openalex   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Development and validation of mRNA expression-based classifiers to predict low-risk thyroid tumors

Frontiers in Endocrinology
BackgroundMolecular variants and fusions in thyroid nodules can provide prognostic information at a population level. However, thyroid cancers harboring the same molecular alterations may exhibit diverse clinical behavior.
Allan Golding, David Bimston, Emma Namiranian, Ellen Marqusee, Gabriel Correa, Evana Valenzuela Scheker, Ruochen Jiang, Yangyang Hao, Mohammed Alshalalfa, Jing Huang, Joshua P. Klopper, Richard T. Kloos, Sara Ahmadi   +12 more
doaj   +1 more source

PPCM and the endocrine system

Heart, 2019
We sincerely thank Dr Jolobe for the response to our paper1 and very much appreciate the interesting addition2 to the discussion on this difficult topic. It is true that autoimmunity has been proposed to play a role in the aetiology of Peripartum Cardiomyopathy (PPCM), as we mention in our introduction.
Lucia Baris, Jérôme Cornette, Mark R Johnson, Karen Sliwa, Jolien W Roos-Hesselink   +4 more
openaire   +4 more sources

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Dental management of patients with endocrine disorders [PDF]

, 2010
Introduction: The endocrine system is responsible for hormonal secretion and is closely related to the central nervous system, as it diversifies its functions through the hypothalamus and pituitary glands.
Carlos Fabuel, Laura, Jiménez Soriano, Yolanda, Sarrión Pérez, María Gracia   +2 more
core   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source