Results 71 to 80 of about 23,029,461 (402)

Reduced model for female endocrine dynamics: Validation and functional variations [PDF]

open access: yesarXiv, 2020
A normally functioning menstrual cycle requires significant crosstalk between hormones originating in ovarian and brain tissues. Reproductive hormone dysregulation may cause abnormal function and sometimes infertility. The inherent complexity in this endocrine system is a challenge to identifying mechanisms of cycle disruption, particularly given the ...
arxiv  

Advances in computational modeling approaches in pituitary gonadotropin signaling [PDF]

open access: yesExpert Opinion on Drug Discovery, 1-15. (2018), 2018
Pituitary gonadotropins play an essential and pivotal role in the control of human and animal reproduction within the hypothalamic-pituitary-gonadal (HPG) axis. The computational modeling of pituitary gonadotropin signaling encompasses phenomena of different natures such as the dynamic encoding of gonadotropin secretion, and the intracellular cascades ...
arxiv   +1 more source

The Endocrine System [PDF]

open access: yes, 1942
Since it has been established that the endocrine glands are essential for growth, an understanding of the morphological and physiological activities of these glands during the process of development of the embryo becomes important.
Venzke, W. G.
core   +2 more sources

Endocrinology and physiology of pseudocyesis [PDF]

open access: yes, 2013
This literature review on pseudocyesis or false pregnancy aims to find epidemiological, psychiatric/psychologic, gynecological and endocrine traits associated with this condition in order to propose neuroendocrine/endocrine mechanisms leading to the ...
Cano, Antonio   +3 more
core   +1 more source

The Ramazzini Institute 13-week pilot study glyphosate-based herbicides administered at human-equivalent dose to Sprague Dawley rats: effects on development and endocrine system

open access: yesEnvironmental Health, 2019
BackgroundGlyphosate-based herbicides (GBHs) are broad-spectrum herbicides that act on the shikimate pathway in bacteria, fungi, and plants. The possible effects of GBHs on human health are the subject of an intense public debate for both its potential ...
F. Manservisi   +17 more
semanticscholar   +1 more source

Immunoregulatory mechanisms of the arachidonic acid pathway in cancer

open access: yesFEBS Letters, EarlyView.
The central role of the arachidonic acid (AA) pathway in anticancer immunity. Enzymes and metabolites of the AA pathway can play both immunosuppressive and immunostimulatory roles in the tumor microenvironment. Therefore, their tailored targeting could be beneficial as a standalone therapy or in combination with current cancer immunotherapy.
Maria Tredicine   +3 more
wiley   +1 more source

Primary hyperparathyroidism having multiple Brown tumors mimicking malignancy

open access: yesIndian Journal of Endocrinology and Metabolism, 2012
Primary hyperparathyroidism is a disease characterized by excessive secretion of parathormone. During the course of this disease, bone loss occurs, particularly depending on resorption of the skeletal system.
Ekram Ullah   +3 more
doaj   +1 more source

AI-Aristotle: A Physics-Informed framework for Systems Biology Gray-Box Identification [PDF]

open access: yesarXiv, 2023
Discovering mathematical equations that govern physical and biological systems from observed data is a fundamental challenge in scientific research. We present a new physics-informed framework for parameter estimation and missing physics identification (gray-box) in the field of Systems Biology.
arxiv  

Overview of air pollution and endocrine disorders [PDF]

open access: yes, 2018
Over recent years, many environmental pollutant chemicals have been shown to possess the ability to interfere in the functioning of the endocrine system and have been termed endocrine disrupting chemicals. These compounds exist in air as volatile or semi-
Darbre, Philippa D.
core   +2 more sources

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

open access: yesFEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga   +6 more
wiley   +1 more source

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