Results 81 to 90 of about 22,716,467 (384)

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Oxytocin Modulation in Mindfulness-Based Pain Management for Chronic Pain

open access: yesLife
In the context of chronic pain management, opioid-based treatments have been heavily relied upon, raising concerns related to addiction and misuse. Non-pharmacological approaches, such as Mindfulness-Based Pain Management, offer alternative strategies ...
Oytun Aygün   +4 more
doaj   +1 more source

Environmental chemical exposures and breast cancer [PDF]

open access: yes, 2016
As a hormone-sensitive condition with no single identifiable cause, breast cancer is a major health problem. It is characterized by a wide range of contributing factors and exposures occurring in different combinations and strengths across a lifetime ...
Plant, J, Stanley, E, Voulvoulis, N
core   +2 more sources

Time, the final frontier

open access: yesMolecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain   +3 more
wiley   +1 more source

The effects of cannabinoids on the endocrine system.

open access: yesEndokrynologia Polska, 2018
Cannabinoids are the derivatives of the cannabis plant, the most potent bioactive component of which is tetrahydrocannabinol (THC). The most commonly used drugs containing cannabinoids are marijuana, hashish, and hashish oil.
M. Borowska   +6 more
semanticscholar   +1 more source

Biology of Sexual Dysfunction [PDF]

open access: yes, 2009
Sexual activity is a multifaceted activity, involving complex interactions between the nervous system, the endocrine system, the vascular system and a variety of structures that are instrumental in sexual excitement, intercourse and satisfaction.
Goyal, N   +4 more
core  

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Association of the hormonal status parameters with the results of the cardiorespiratory exertion test in athletes

open access: yesКлиническая практика, 2018
The aim of this study was to identify the specifics of the endocrine system functioning in males professionally involved in sports. We have observed 70 sportsmen and 70 students of the Maritime Academy. The check-up included the following procedures: the
S. D. Megeryan
doaj   +1 more source

Molecular mechanisms of endocrine disruptors: Interference with the endocrine system activity [PDF]

open access: yes, 2018
Endocrine disrupting chemicals (EDCs) are an heterogeneous group of compounds able to interfere with hormonal functions by mimicking the endogenous hormones.
Falco, De, Laforgia, Vincenza
core  

Salivary biomarkers in psychobiological medicine. [PDF]

open access: yes, 2006
The value of salivary biomarkers for diagnostic and prognostic assessments has become increasingly well established in medicine, pharmacology, and dentistry. Certain salivary components mirror the neuro-endocrine status of the organism.
Chiappelli, Francesco   +2 more
core   +2 more sources

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