Comorbidities in congenital heart disease: different patterns in childhood and adulthood
Background Existing studies were no exploration of the association between congenital heart disease (CHD) in children and comorbidities. This study was to assess the prevalence and number of comorbidities in CHD among children and adults, and to compare ...
Zhibao Ding+3 more
doaj +1 more source
Screening of endocrine organ-specific humoral autoimmunity in 47,XXY Klinefelter's syndrome reveals a significant increase in diabetes-specific immunoreactivity in comparison with healthy control men. [PDF]
The aim of this study was to evaluate the frequency of humoral endocrine organ-specific autoimmunity in 47,XXY Klinefelter’s syndrome (KS) by investigating the autoantibody profile specific to type 1 diabetes (T1DM), Addison’s disease (AD), Hashimoto ...
ANZUINI, Antonella+7 more
core +1 more source
Chromogranin A: From Laboratory to Clinical Aspects of Patients with Neuroendocrine Tumors [PDF]
Background. Neuroendocrine tumors (NETs) are characterized by having behavior and prognosis that depend upon tumor histology, primary site, staging, and proliferative index.
Baldelli, Roberto+8 more
core +1 more source
Mechanisms that Lead to Disease of the Endocrine System in Animals [PDF]
Endocrine glands are collections of specialized cells that synthesize, store, and release their secretions directly into the blood stream. They are sensing and signalling devices located in the extracellular fluid compartment and are capable of responding to changes in the internal and external environments to coordinate a multiplicity of activities ...
Charles C. Capen, Sharron L. Martin
openaire +3 more sources
Immune checkpoint inhibitor-induced endocrinopathies: a possible indicator of improved survival [PDF]
Objective: To evaluate the association between the patients’ characteristics and the development of endocrine toxicity and to assess the association between endocrine-related adverse effects (ERAE) development and mortality.
Mariana Ornelas+6 more
doaj +1 more source
Does vitamin D play a role in autoimmune endocrine disorders? A proof of concept [PDF]
In the last few years, more attention has been given to the "non-calcemic" effect of vitamin D. Several observational studies and meta-analyses demonstrated an association between circulating levels of vitamin D and outcome of many common diseases ...
Altieri, Barbara+15 more
core +1 more source
One special question to start with: can HIF/NFkB be a target in inflammation? [PDF]
Hypoxia and Inflammation are strictly interconnected with important consequences at clinical and therapeutic level. While cell and tissue damage due to acute hypoxia mostly leads to cell necrosis, in chronic hypoxia, cells that are located closer to ...
CARNEVALE, ILARIA+8 more
core +1 more source
EPA’s Endocrine Disruptor Screening Program (EDSP)
People have asked questions in recent years concerning the effects that certain chemicals may have on the endocrine system of humans and wildlife. Laboratory studies have produced evidence that show various chemicals disrupt the endocrine systems of ...
Frederick M. Fishel
doaj +5 more sources
Rheumatic manifestations of hypothyroidism
The rheumatic manifestations of endocrine diseases are well-known. The endocrine system has a complex effect on the structure and function of musculoskeletal tissues.
L. V. Teplova+3 more
doaj +1 more source
Environmental chemical exposures and breast cancer [PDF]
As a hormone-sensitive condition with no single identifiable cause, breast cancer is a major health problem. It is characterized by a wide range of contributing factors and exposures occurring in different combinations and strengths across a lifetime ...
Plant, J, Stanley, E, Voulvoulis, N
core +2 more sources