Interleukin-10 Attenuates Liver Fibrosis Exacerbated by Thermoneutrality
Background: Crosstalk between brown adipose tissue (BAT) and the liver is receiving increasing attention. This study investigated the effect of BAT dysfunction by thermoneutral (TN) housing on liver fibrosis in mice and examined the effect of secreted ...
Ha Thi Nga +17 more
doaj +1 more source
Immune Checkpoint Inhibitors and Endocrine Disorders: A Position Statement from the Korean Endocrine Society [PDF]
Immune checkpoint inhibitors (ICIs) including an anti-cytotoxic T-lymphocyte-associated antigen 4 inhibitor, anti-programmed cell death protein 1 (PD-1) inhibitors, and anti-PD-ligand 1 inhibitors are representative therapeutics for various malignancies.
Hyemi Kwon +14 more
doaj +1 more source
Initial experience of dedicated breast PET imaging of ER+ breast cancers using [F-18]fluoroestradiol. [PDF]
Dedicated breast positron emission tomography (dbPET) is an emerging technology with high sensitivity and spatial resolution that enables detection of sub-centimeter lesions and depiction of intratumoral heterogeneity.
Chien, Amy J +10 more
core +2 more sources
Endocrine FGFs: evolution, physiology, pathophysiology, and pharmacotherapy
The human fibroblast growth factor (FGF) family comprises 22 structurally related polypeptides that play crucial roles in neuronal functions, development, and metabolism.
Nobuyuki eItoh +2 more
doaj +1 more source
Endocrine pathologies in the conditions of chemotherapy
BACKGROUND. Cancer is the leading cause of death in the world. Chemotherapy is the most effective and in some cases the only method of treating oncopathology.
A.V. Garnytska, O.S. Orlyk
doaj +1 more source
Extra virgin olive oil and cardiovascular diseases: benefits for human health [PDF]
The cardioprotective properties of Mediterranean Diet were demonstrated for the first time from the Seven Country Study. In the last few decades, numerous epidemiological studies, as well as intervention trial, confirmed this observation, pointing out ...
Cammisotto, Vittoria +8 more
core +1 more source
Introduction and Purpose Hashimoto’s disease is the most common reason of hypothyroidism. Usually, it is easy to recognize and treat. However, under certain circumstances, it may develop into the most severe manifestation of hypothyroidism known as ...
Karol Bochyński +9 more
doaj +1 more source
Thyroid Hormone Availability and Action during Brain Development in Rodents
Thyroid hormones (THs) play an essential role in the development of all vertebrates; in particular adequate TH content is crucial for proper neurodevelopment.
Soledad Bárez-López +3 more
doaj +1 more source
The Tryptophan and Kynurenine Pathway Involved in the Development of Immune-Related Diseases
The tryptophan and kynurenine pathway is well-known to play an important role in nervous, endocrine, and immune systems, as well as in the development of inflammatory diseases.
Ai Tsuji +8 more
semanticscholar +1 more source
Targeting trafficking as a therapeutic avenue for misfolded GPCRs leading to endocrine diseases
G protein-coupled receptors (GPCRs) are plasma membrane proteins associated with an array of functions. Mutations in these receptors lead to a number of genetic diseases, including diseases involving the endocrine system.
Alfredo Ulloa-Aguirre +3 more
doaj +1 more source

