Glucocorticoids (GCs) are widely prescribed for their anti-inflammatory and immunosuppressive properties as a treatment for a variety of diseases. The use of GCs is associated with important side effects, including diabetogenic effects.
Etienne Delangre +8 more
doaj +1 more source
Treatment of a mixed acinar-endocrine carcinoma with uptake on 68Gallium-DOTATOC positron emission tomography-computed tomography : a case report [PDF]
The case of a 35-year old female patient with a diagnosis of metastatic mixed acinar-endocrine carcinoma (MAEC) is investigated in the present study.
De Both, Anneleen +5 more
core +2 more sources
Endocrine therapy resistance in Luminal Breast Cancer is a significant issue to be tackled, but currently, no specific biomarker could be used to anticipate this event.
Yohana Azhar +3 more
doaj +1 more source
Ipilimumab, not just another anti-cancer therapy: hypophysitis as side effect illustrated by four case-reports [PDF]
Ipilimumab is a monoclonal antibody that blocks cytotoxic T-lymphocyte antigen4 (CTLA-4), an inhibitory molecule typically expressed on T cells. Blockade of CTLA-4 induces an overall activation of T cells, including an immune-mediated anti-tumour ...
Brochez, Lieve +4 more
core +2 more sources
Notch Signaling Pathway and Endocrine Resistance in Breast Cancer
Nearly 70% of breast cancers express the estrogen receptor (ER) and are hormone-dependent for cell proliferation and survival. Anti-estrogen therapies with aromatase inhibitors (AIs), selective estrogen receptor modulators (SERMs) or selective estrogen ...
Jing-Wen Bai +6 more
doaj +1 more source
A qualitative comparison of how older breast cancer survivors process treatment information regarding endocrine therapy. [PDF]
BACKGROUND:It remains unclear how information about aromatase inhibitors (AI) impacts women's decision-making about persistence with endocrine therapy.
Green, Emily +4 more
core +4 more sources
Surgery versus primary endocrine therapy for operable primary breast cancer in elderly women (70 years plus). [PDF]
While younger women with early-stage, oestrogen-sensitive breast cancer are almost invariably treated with surgery plus endocrine therapy, (which deprives the cancer of the hormonal stimulus that induces its growth), women over the age of 70 years are ...
Bates +78 more
core +1 more source
The research progress of endocrine therapy combined with targeted therapy for triple-positive breast cancer [PDF]
Triple-positive breast cancer (TPBC) refers to breast cancer with positive expression of estrogen receptor, progesterone receptor and human epidermal growth factor receptor 2 (HER2), accounting for 5%-10% of all pathological types of breast cancer.
CAO Xiaoshan, CONG Binbin
doaj +1 more source
Initial experience of dedicated breast PET imaging of ER+ breast cancers using [F-18]fluoroestradiol. [PDF]
Dedicated breast positron emission tomography (dbPET) is an emerging technology with high sensitivity and spatial resolution that enables detection of sub-centimeter lesions and depiction of intratumoral heterogeneity.
Chien, Amy J +10 more
core +2 more sources
Zurich Consensus: Statement of German Experts on St. Gallen Conference 2011 on Primary Breast Cancer (Zurich 2011) [PDF]
Every 2 years, the International Consensus Conference on the Treatment of Primary Breast Cancer takes place in St. Gallen. Given that the concept of the St.
Beckmann, Matthias W. +27 more
core +1 more source

