Results 21 to 30 of about 466,117 (305)

Underlying mechanisms of glucocorticoid-induced β-cell death and dysfunction: a new role for glycogen synthase kinase 3

open access: yesCell Death and Disease, 2021
Glucocorticoids (GCs) are widely prescribed for their anti-inflammatory and immunosuppressive properties as a treatment for a variety of diseases. The use of GCs is associated with important side effects, including diabetogenic effects.
Etienne Delangre   +8 more
doaj   +1 more source

Treatment of a mixed acinar-endocrine carcinoma with uptake on 68Gallium-DOTATOC positron emission tomography-computed tomography : a case report [PDF]

open access: yes, 2017
The case of a 35-year old female patient with a diagnosis of metastatic mixed acinar-endocrine carcinoma (MAEC) is investigated in the present study.
De Both, Anneleen   +5 more
core   +2 more sources

p53 Mutation as Plausible Predictor for Endocrine Resistance Therapy in Luminal Breast Cancer [version 2; peer review: 2 approved]

open access: yesF1000Research, 2022
Endocrine therapy resistance in Luminal Breast Cancer is a significant issue to be tackled, but currently, no specific biomarker could be used to anticipate this event.
Yohana Azhar   +3 more
doaj   +1 more source

Ipilimumab, not just another anti-cancer therapy: hypophysitis as side effect illustrated by four case-reports [PDF]

open access: yes, 2014
Ipilimumab is a monoclonal antibody that blocks cytotoxic T-lymphocyte antigen4 (CTLA-4), an inhibitory molecule typically expressed on T cells. Blockade of CTLA-4 induces an overall activation of T cells, including an immune-mediated anti-tumour ...
Brochez, Lieve   +4 more
core   +2 more sources

Notch Signaling Pathway and Endocrine Resistance in Breast Cancer

open access: yesFrontiers in Pharmacology, 2020
Nearly 70% of breast cancers express the estrogen receptor (ER) and are hormone-dependent for cell proliferation and survival. Anti-estrogen therapies with aromatase inhibitors (AIs), selective estrogen receptor modulators (SERMs) or selective estrogen ...
Jing-Wen Bai   +6 more
doaj   +1 more source

A qualitative comparison of how older breast cancer survivors process treatment information regarding endocrine therapy. [PDF]

open access: yes, 2019
BACKGROUND:It remains unclear how information about aromatase inhibitors (AI) impacts women's decision-making about persistence with endocrine therapy.
Green, Emily   +4 more
core   +4 more sources

Surgery versus primary endocrine therapy for operable primary breast cancer in elderly women (70 years plus). [PDF]

open access: yes, 2014
While younger women with early-stage, oestrogen-sensitive breast cancer are almost invariably treated with surgery plus endocrine therapy, (which deprives the cancer of the hormonal stimulus that induces its growth), women over the age of 70 years are ...
Bates   +78 more
core   +1 more source

The research progress of endocrine therapy combined with targeted therapy for triple-positive breast cancer [PDF]

open access: yesZhongguo aizheng zazhi, 2023
Triple-positive breast cancer (TPBC) refers to breast cancer with positive expression of estrogen receptor, progesterone receptor and human epidermal growth factor receptor 2 (HER2), accounting for 5%-10% of all pathological types of breast cancer.
CAO Xiaoshan, CONG Binbin
doaj   +1 more source

Initial experience of dedicated breast PET imaging of ER+ breast cancers using [F-18]fluoroestradiol. [PDF]

open access: yes, 2019
Dedicated breast positron emission tomography (dbPET) is an emerging technology with high sensitivity and spatial resolution that enables detection of sub-centimeter lesions and depiction of intratumoral heterogeneity.
Chien, Amy J   +10 more
core   +2 more sources

Zurich Consensus: Statement of German Experts on St. Gallen Conference 2011 on Primary Breast Cancer (Zurich 2011) [PDF]

open access: yes, 2011
Every 2 years, the International Consensus Conference on the Treatment of Primary Breast Cancer takes place in St. Gallen. Given that the concept of the St.
Beckmann, Matthias W.   +27 more
core   +1 more source

Home - About - Disclaimer - Privacy