Results 91 to 100 of about 600,211 (346)

Perspective: from molecular endocrinology of mouse to genomic endocrinology of animals.

, 2008
This short perspective explores some ways in which new genomic methodologies impact the study of endocrine signaling. Emphasis is put on the impact of studying species which are not molecular biology models.
Robinson-Rechavi, M.
core   +1 more source

Biochemically Constrained Multi‐Omics Integration Reveals Protein–Metabolite Dependencies Across Diseases

Advanced Science, EarlyView.
ProMetNet introduces a biologically constrained deep learning framework for proteo‐metabolomic integration by embedding Reactome‐derived pathway topology into neural networks. It captures non‐linear molecular dependencies and pathway‐level metabolic reorganization, enabling interpretable discrimination.
Minghui Zhao, Na Zhou, Ruotong Liu, Xiaofei Li, Jian Li, Fuzhong Xue, Qingzhen Hou   +6 more
wiley   +1 more source

MHS status and salivary cortisol concentration in individually housed pigs

Acta Agriculturae Slovenica, 2006
Salivary cortisol was evaluated as stress measure in pigs of two malignant hyperthermia (MH) genotypes (NN and Nn), housed individually in metabolic cages and in comfortable large pens with straw.
Nataša SIARD, Ivan ŠTUHEC
doaj   +1 more source

ADIPOSITY-BASED CHRONIC DISEASE AS A NEW DIAGNOSTIC TERM: THE AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY POSITION STATEMENT.

Endocrine Practice, 2017
The American Association of Clinical Endocrinologists (AACE) and American College of Endocrinology (ACE) have created a chronic care model, advanced diagnostic framework, clinical practice guidelines, and clinical practice algorithm for the comprehensive
J. Mechanick, D. Hurley, W. Garvey
semanticscholar   +1 more source

Advances in comparative endocrinology : vol. VIII [PDF]

, 2016
Ponències presentades al 10th Congress of the Iberian Association of Comparative Endocrinology (AIEC), celebrat a la Universitat Jaume I, els dies 23 al 25 de setembre de 2015Les diverses comunicacions presentades al 10è Congrés de la Asociación Ibérica ...
Cerdá-Reverter, José Miguel, Calduch-Giner, Josep A., Calduch-Giner, Josep, Josep Calduch Giner, Pérez Sánchez, Jaume, Jaume Pérez Sánchez, José Miguel Cerdá Reverter, Pérez-Sánchez, Jaume, Cerdá Reverter, José Miguel   +8 more
core   +1 more source

Nucleoside‐Modified mRNA Encoding Alpha‐Galactosidase A Ameliorates Fabry Disease Phenotypes in Human IPSC‐Derived Cardiomyocytes

Advanced Science, EarlyView.
Human iPSC‐derived Fabry cardiomyocytes exhibited broad transcriptional dysregulation, apoptosis, mitochondrial dysfunction, impaired reactive oxygen species handling, altered contractility, and abnormal calcium transient decay, potentially mediated by phospholamban hyperphosphorylation.
Malte Juchem, Lea Oehlsen, Sedef Ersoy, Jia Li Ye, Natalie Weber, Elisa Mohr, Wilson Agyapong, Junqing Liu, Maximilian Fuchs, Ke Xiao, Christopher Jahn, Reto Eggenschwiler, Tobias Cantz, Julia Beimdiek, Falk F. R. Buettner, Theresia Kraft, Jan Hegermann, Ivonne J. Knorr, Lisa Ernst, Linda Feldbrügge, Resa Puffert, Kevin Schmidt, Christian Bär, Jeannine Hoepfner, Thomas Thum   +24 more
wiley   +1 more source

Niche‐Mediated Neural Priming Enables Robust and Scalable Generation of Human Choroid Plexus Organoids

Advanced Science, EarlyView.
Compared to E8, mTeSR1 culture downregulated WNT and TGF‑β signaling, and upregulated neural differentiation pathways, enhancing neural priming. Under skin organoid induction conditions, mTeSR1‑cultured hESCs generated organoids with significantly higher neuroepithelial differentiation.
Zhongliang Chen, Liangxia Jiang, Xianbin Wang, Lili Zhong, Rongcan Luo, Min Su, Liangzhao Chu, Peng Luo   +7 more
wiley   +1 more source

Familial association of polycystic ovary syndrome (PCOS) in women attending the gynaecological endocrinology clinic at Groote Schuur Hospital [PDF]

, 2010
Includes bibliographical references (leaves 60-65).Polycystic ovary syndrome (PCOS) is the commonest endocrinopathy in women of reproductive age, affecting 5-10% of women in the general population.
Edelstein, Sascha
core   +1 more source

TH/TRs–COL11A2 Axis Mediates Loss of a Differentiated Astrocyte State in Hypogyrified Brains

Advanced Science, EarlyView.
Using a gyrencephalic congenital hypothyroidism pig model, this study reveals cerebral atrophy and cortical hypogyrification. Single‐cell sequencing identifies astrocytes as major TH‐responsive cells, with the COL11A2‐enriched Astro‐2 state nearly absent.
Ying Zhang, Xiao Wang, Hongyan Ma, Pengcheng Lyu, Shuangjie Tian, Ruojun Zong, Jiani Chen, Gang Ren, Yongjiang Yang, Zichen Yang, Guosong Qin, Naishi Li, Yanfang Wang, Jianwei Jiao, Jianguo Zhao   +14 more
wiley   +1 more source

Comment on “Association Between Triglyceride-Glucose Index and Malignant Risk in Thyroid Nodules: A Cross-Sectional Analysis” [Letter]

Journal of Inflammation Research
Zhiwei Hu,1,2 Hua Dong,2 Yuchang Fei3 1Zhejiang Chinese Medical University, Hangzhou, Zhejiang, 310000, People’s Republic of China; 2Department of Endocrinology, The First People’s Hospital of Jiashan, Jiashan Hospital Affiliated of ...
Hu Z, Dong H, Fei Y
doaj