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Wiener Medizinische Wochenschrift, 2016
Endocytosis is a fundamental cell biological process, which carries out essential functions in a polarized epithelial cell such as enterocytes provided with a huge surface area of the brush border membrane. Major tasks of enterocytes, which are regulated by endocytic signals, are digestion and absorption of nutrients and drugs/pharmacological agents ...
Jan de Laffolie +3 more
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Endocytosis is a fundamental cell biological process, which carries out essential functions in a polarized epithelial cell such as enterocytes provided with a huge surface area of the brush border membrane. Major tasks of enterocytes, which are regulated by endocytic signals, are digestion and absorption of nutrients and drugs/pharmacological agents ...
Jan de Laffolie +3 more
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Phosphoinositides in endocytosis
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2015The internalization and subsequent endosomal trafficking of proteins and membrane along the endocytic pathway is a fundamental cellular process. Over the last two decades, this pathway has emerged to be subject to extensive regulation by phosphoinositides (PIs), phosphorylated derivatives of the minor membrane phospholipid phosphatidylinositol ...
York Posor +2 more
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Endocrine Reviews, 1995
I. Introduction THE transport of proteins, hormones, and nutrients to different locations within a cell is an essential process for many of the functions of eukaryotic cells. It is of particular importance in complex multicellular organisms to enable the cells to communicate with one another.
Phillip J. Robinson, Jun-Ping Liu
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I. Introduction THE transport of proteins, hormones, and nutrients to different locations within a cell is an essential process for many of the functions of eukaryotic cells. It is of particular importance in complex multicellular organisms to enable the cells to communicate with one another.
Phillip J. Robinson, Jun-Ping Liu
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Endocytosis and the cytoskeleton
2002In this review we describe the potential roles of the actin cytoskeleton in receptor-mediated endocytosis in mammalian cells and summarize the efforts of recent years in establishing a relationship between these two cellular functions. With molecules such as dynamin, syndapin, HIP1R, Abp1, synaptojanin, N-WASP, intersectin, and cortactin a set of ...
Michael M. Kessels, Britta Qualmann
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Trends in Biochemical Sciences, 1986
Yeast is emerging as a promising cell system to study the mechanisms underlying endocytosis and its relationship with other cellular pathways such as secretion and hormone response.
Riezman, H +2 more
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Yeast is emerging as a promising cell system to study the mechanisms underlying endocytosis and its relationship with other cellular pathways such as secretion and hormone response.
Riezman, H +2 more
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Journal of Cell Science, 2000
In mammalian cells, cargo can be endocytosed via clathrin-coated pits, the clathrin-independent pathway or caveolae. In yeast cells the morphology of the internalization step is not yet defined.
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In mammalian cells, cargo can be endocytosed via clathrin-coated pits, the clathrin-independent pathway or caveolae. In yeast cells the morphology of the internalization step is not yet defined.
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Current Opinion in Cell Biology, 2002
The GTPase dynamin is essential for endocytosis, but its mechanism of action remains uncertain. Structures of its GTPase domain, as well as that of assembled dynamin, have led to major advances in understanding the structural basis of its mode of action.
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The GTPase dynamin is essential for endocytosis, but its mechanism of action remains uncertain. Structures of its GTPase domain, as well as that of assembled dynamin, have led to major advances in understanding the structural basis of its mode of action.
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Advanced Drug Delivery Reviews, 1998
Vesicular coat proteins mediate the formation of nascent vesicles and select the cargo to be incorporated therein. As additional coat proteins are discovered that regulate vesicular traffic along very specific intracellular pathways, the possibility looms of regulating the intracellular trafficking and targeting of therapeutic agents by modulation of ...
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Vesicular coat proteins mediate the formation of nascent vesicles and select the cargo to be incorporated therein. As additional coat proteins are discovered that regulate vesicular traffic along very specific intracellular pathways, the possibility looms of regulating the intracellular trafficking and targeting of therapeutic agents by modulation of ...
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Systems Dynamics in Endocytosis
Traffic, 2014AbstractThe endocytic system acts at the crossroads of different cellular activities to play a central role in the regulation of cell signaling and membrane dynamics. An European Molecular Biology Organization (EMBO) conference held in October 2013 in Villars‐sur‐Ollon gathered researchers from all over the world to present their latest findings on the
Fürthauer, Maximilian +1 more
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Physiologia Plantarum, 1990
Endocytosis in animal cells has been heavily documented. Both fluid‐phase and receptor‐mediated modes of uptake have been frequently studied, and the endocytic pathway is well defined. This contrasts markedly with the situation in plants where our knowledge of this process is still rudimentary.
David G. Robinson, Stefan Hillmer
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Endocytosis in animal cells has been heavily documented. Both fluid‐phase and receptor‐mediated modes of uptake have been frequently studied, and the endocytic pathway is well defined. This contrasts markedly with the situation in plants where our knowledge of this process is still rudimentary.
David G. Robinson, Stefan Hillmer
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