Results 151 to 160 of about 1,483,639 (353)

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

Solovian and New Growth Theory from the Perspective of Allyn Young on Macroeconomic Increasing Returns [PDF]

This paper evaluates, from an Allyn Youngian perspective, the neoclassical Solow model of growth and the associated empirical estimates of the sources of growth based on it.
Roger Sandilands
core  

Prevascularization promotes endogenous cell-mediated angiogenesis by upregulating the expression of fibrinogen and connective tissue growth factor in tissue-engineered bone grafts [PDF]

, 2018
Pengzhen Cheng, Lin Li, Yi Gao, Tianqing Cao, Huijie Jiang, Jimeng Wang, Junqin Li, Shuaishuai Zhang, Yue Song, Bin Liu, Chunmei Wang, Liu Yang, Guoxian Pei   +12 more
openalex   +1 more source

Atomic Size Misfit for Electrocatalytic Small Molecule Activation

Advanced Functional Materials, EarlyView.
This review explores the application and mechanisms of atomic size misfit in catalysis for small molecule activation, focusing on how structural defects and electronic properties can effectively lower the energy barriers of chemical bonds in molecules like H2O, CO2, and N2.
Ping Hong, Changfan Xu, Huaping Zhao, Yong Lei   +3 more
wiley   +1 more source

Science in the Third Dimension of R&D [PDF]

We study a Schumpeterian model of long-run growth with endogenous fertility and with three interacting dimensions of innovation. Scientific research is the fundamental dimension of innovation that creates new technological knowledge.
Attar, Mustafa A.
core   +1 more source

3D Multicellular Scaffold Based Model for Advancing Bone Disorder Research

Advanced Functional Materials, EarlyView.
A scalable 3D multicellular in vitro bone model engineered by integrating osteoblasts, osteoclasts, and endothelial cells on biodegradable scaffolds. The system recapitulates key features of human bone remodeling and disease pathology. As a proof of concept, the model mimics osteogenesis imperfecta, demonstrating its potential as a physiologically ...
Gali Guterman‐Ram, Majd Machour, Janette Zavin, Roy Meretzki, Reut Lev‐Ari, Shulamit Levenberg   +5 more
wiley   +1 more source

Monitoring endogenous growth of open-vent volcanoes by balancing thermal and SO₂ emissions data derived from space. [PDF]

Sci Rep, 2019
Coppola D, Laiolo M, Massimetti F, Cigolini C.   +3 more
europepmc   +1 more source

THE EFFECTS OF THE TRANSPORTATION COSTS IN R&D TECHNOLOGY SECTOR ON THE ENDOGENOUS GRWOTH [PDF]

The paper centers on investigating theoretically how the transportation costs of R&D technology, none of the transportation costs in final goods and intermediate inputs, affect the long-run endogenous economic growth.
Youngwan Goo
core  

Endogenous institutions and economic growth: evidence from China [PDF]

, 2020
Li Zhao, Yujing Chu
openalex   +1 more source