Results 121 to 130 of about 73,519 (232)
Definition and variation of human endogenous retrovirus H
Virology, 2004 We defined the abundant human endogenous retrovirus group HERV-H based on pol similarity. Among 3661 pol-containing elements, 1124 integrations were similar to HERV-H RGH2 pol using translated pol sequences. A clustering procedure lessened these to 234 representatives, amenable to detailed study.
Jern, Patric +2 more
openaire +2 more sources
European Journal of Immunology, Volume 56, Issue 2, February 2026.Phagocytosis of yeast activates recruitment of proteases and trafficking factors from the secretory and endosomal pathways to the IRAP compartment and subsequently phagosomes, promoting cross‐presentation. In the absence of Sec22b, IRAP endosome and phagosome maturation to late endosomes is accelerated.
Alice Senni +7 more
wiley +1 more source
Endogenous MMTV proviruses induce susceptibility to both viral and bacterial pathogens.
PLoS Pathogens, 2006 Most inbred mice carry germline proviruses of the retrovirus, mouse mammary tumor virus (MMTV) (called Mtvs), which have multiple replication defects. A BALB/c congenic mouse strain lacking all endogenous Mtvs (Mtv-null) was resistant to MMTV oral and ...
Sanchita Bhadra +3 more
doaj +1 more source
European Journal of Immunology, Volume 56, Issue 2, February 2026.Mechanism of action of the intestinal microbiota on CNS autoimmune diseases. Environmental factors shape gut microbiota composition; dysbiosis alters microbial metabolites and antigenic signals. These modulate innate and adaptive immunity, affect barrier integrity, and influence CNS‐resident cells such as microglia and astrocytes, contributing to ...
Matteo Ceccon, Francesca Ronchi
wiley +1 more source
Superior lentiviral vectors designed for BSL-0 environment abolish vector mobilization. [PDF]
, 2018 Lentiviral vector mobilization following HIV-1 infection of vector-transduced cells poses biosafety risks to vector-treated patients and their communities.
Bi, Yanmin +7 more
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Process Systems Engineering in Precision Medicine: Opportunities in Autologous CAR‐T Therapy
Engineering in Life Sciences, Volume 26, Issue 2, February 2026.ABSTRACT Autologous chimeric antigen receptor (CAR)‐T therapies have given hope to many cancer patients whose other lines of treatment have failed. Unfortunately, limited manufacturing capability has resulted in many patients dying while on a waitlist.
B. Wayne Bequette
wiley +1 more source
eLife, 2017 Primates have co-opted a viral gene to produce an envelope protein that prevents infection by the HERV-T virus and likely contributed to the extinction of this virus.
Julia H Wildschutte, John M Coffin
doaj +1 more source
Relapsing-remitting multiple sclerosis: advances in disease-modifying therapies [PDF]
, 2015 Multiple sclerosis is a demyelinating disease affecting the central nervous system. It is the most prevalent disabling neurological condition among young adults, with onset typically between 20 and 40 years of age. Infiltrating immune cells and microglia
Kay, Kathleen Alexandra
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International Journal of Cancer, Volume 158, Issue 3, Page 511-526, 1 February 2026.Abstract Viral infections play a significant role in cancer development, making detecting viral signatures a promising approach for early cancer diagnosis. Circulating free DNA (cfDNA), released into the bloodstream by tumors and other cells, has emerged as a powerful biomarker for non‐invasive cancer screening.
Richard Donkor Amponsah +4 more
wiley +1 more source
Generation of Transgenic Mice to Evaluate Promoter Activity and Specificity of Two Human Endogenous Retrovirus Long Terminal Repeats = Untersuchungen zur Promotor-Aktivität und -Spezifität von zwei Long Terminal Repeats humaner endogener Retroviren in transgenen Mäusen [PDF]
, 2003 Generation of Transgenic Mice to Evaluate Promoter Activity and Specificity of two Human Endogenous Retrovirus Long Terminal Repeats Human Endogenous Retrovirus Long Terminal Repeats (HERV-LTRs) comprise 1.8% of the human genome (52.7 Mb).
Schönfeld, Regine Margarete
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