Results 191 to 200 of about 73,519 (232)
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Detection of porcine endogenous retrovirus in xenotransplantation
Reproductive Biology, 2014Xenotransplantation can provide a virtually limitless supply of cells, tissues and organs for a variety of therapeutic procedures. Cells and tissues for use in human transplantation procedures could be supplied using material taken from pigs. However, there is a potential risk of transmission of porcine infectious agents, including porcine endogenous ...
Joanna, Gola, Urszula, Mazurek
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Endogenous retrovirus expression in testis and epididymis
Biochemical Society Transactions, 2007ERVs (endogenous retroviruses), which comprise 8–10% of mouse and human genomes, are present in thousands of copies, ranging in size from complete 9 kb virus to truncated partial sequences. Despite well-documented differential expression of ERVs in normal and diseased tissues, their biological significance remains controversial. Work in this laboratory
R C, Crowell, A A, Kiessling
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Organization of Endogenous Retrovirus Genes
1980In mammals virogenes are multiple copy elements. Estimates of the number of copies lie between five and several hundred. This wide range results from variations in the copy number of different virogenes and from technieal considerations. The conventional means for determining the number of copies of a particular gene in mammalian DNA is to follow the ...
David R. Strayer, David H. Gillespie
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Porcine endogenous retrovirus and other viruses in xenotransplantation
Current Opinion in Organ Transplantation, 2009Potential transmission of zoonotic porcine viruses is a major safety issue in xenotransplantation. This review will first summarize recent studies involving transmission and control of the major concern, porcine endogenous retrovirus (PERV). Second, the potential for zoonotic transfer and safety measures required against other viruses of concern will ...
Scobie, Linda, Takeuchi, Yasuhiro
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Transfection by exogenous and endogenous murine retrovirus DNAs
Cell, 1979Abstract We have used DNA transfection to study the endogenous retrovirus genomes inherited by uninfected mouse cells. Quantitative assays for infectious DNAs of ecotropic and xenotropic murine leukemia viruses (MuLVs) were developed using donor DNAs of cells that were exogenously infected with ecotropic Moloney, AKR or BALB MuLVs, or with xenotropic ...
Copeland, N G, Cooper, G M
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Endogenous retrovirus evolution in mammalian genomes
2018Endogenous retroviruses (ERVs), derived from exogenous retroviruses (XRVs), comprise about 5 to 10 % of most mammalian genomes. We can study retroviral infection which originated millions years ago and understand long term evolution of infectious viruses by working on ERVs.
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Characterizing Endogenous Protein Complexes with Biological Mass Spectrometry
Chemical Reviews, 2022Michal Sharon
exaly