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Human Endogenous Retroviruses and Diseases [PDF]
MedCommHuman endogenous retroviruses (HERVs), remnants of ancient retroviral infections, comprise nearly 8% of the human genome and play dual roles in physiological regulation and disease pathogenesis.
Can Chen +9 more
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Human-Specific Endogenous Retroviruses [PDF]
Scientific World Journal, The, 2007 This review focuses on a small family of human-specific genomic repetitive elements, presented by 134 members that shaped ~330 kb of the human DNA. Although modest in terms of its copy number, this group appeared to modify the human genome activity by ...
Anton Buzdin
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Cellular and Molecular Life Sciences, 2008 The genomes of vertebrates contain sequences that are similar to present-day exogenous retroviruses. Such sequences, called endogenous retroviruses (ERVs), have resulted from ancestral germ line infections by exogenous retroviruses which have thereafter been transmitted in a Mendelian fashion. By analogy to exogenous tumorigenic retroviruses, ERVs have
K, Ruprecht +4 more
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The discovery of endogenous retroviruses [PDF]
Retrovirology, 2006 When endogenous retroviruses (ERV) were discovered in the late 1960s, the Mendelian inheritance of retroviral genomes by their hosts was an entirely new concept.
Weiss Robin A
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How Active Are Porcine Endogenous Retroviruses (PERVs)?
Viruses, 2016 Porcine endogenous retroviruses (PERVs) represent a risk factor if porcine cells, tissues, or organs were to be transplanted into human recipients to alleviate the shortage of human transplants; a procedure called xenotransplantation.
Joachim Denner
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Porcine Endogenous Retroviruses and Xenotransplantation, 2021
Viruses, 2021 Porcine endogenous retroviruses (PERVs) are integrated in the genome of all pigs, and some of them are able to infect human cells. Therefore, PERVs pose a risk for xenotransplantation, the transplantation of pig cells, tissues, or organ to humans in ...
Joachim Denner
exaly +3 more sources
Diversity and evolutionary history of endogenous retroviruses in the genome of Manis pentadactyla [PDF]
Microbiology SpectrumEndogenous retroviruses (ERVs), remnants of ancient viral infections integrated into host genomes, serve as invaluable molecular fossils for studying viral evolution.
Tiancheng Zhang +4 more
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The making and breaking of insect endogenous retroviruses [PDF]
The EMBO JournalRetroelements are main constituents of eukaryotic genomes. Recent work by Senti et al (2025) reports that retrotransposons and endogenous retroviruses occupy specific spatiotemporal niches in the fly ovary, where they are kept in check by tissue-specific
Rebecca Halbach, Ronald P van Rij
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Asparaginase-like protein 1 and human endogenous retroviruses link immune and gene dysregulation in dementia [PDF]
Frontiers in Cellular and Infection MicrobiologyDementia is increasingly recognized as a condition characterized not only by neurodegeneration but also by significant immune alterations, with potential consequences for both humoral immunity and peripheral gene regulation.
Elena Rita Simula +7 more
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Endogenous retroviruses of the chicken genome [PDF]
Biology Direct, 2008 We analyzed the chicken (Gallus gallus) genome sequence to search for previously uncharacterized endogenous retrovirus (ERV) sequences using ab initio and combined evidence approaches.
Jordan I King +3 more
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