Mammalian Endogenous Retroviruses
Microbiology Spectrum, 2015 ABSTRACT Over 40% of mammalian genomes comprise the products of reverse transcription. Among such retrotransposed sequences are those characterized by the presence of long terminal repeats (LTRs), including the endogenous retroviruses (ERVs), which are inherited genetic elements closely resembling the proviruses formed following exogenous ...
Dixie L, Mager, Jonathan P, Stoye
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Highly Variable Genomic Landscape of Endogenous Retroviruses in the C57BL/6J Inbred Strain, Depending on Individual Mouse, Gender, Organ Type, and Organ Location. [PDF]
, 2017 Transposable repetitive elements, named the "TREome," represent ~40% of the mouse genome. We postulate that the germ line genome undergoes temporal and spatial diversification into somatic genomes in conjunction with the TREome activity.
Cho, Kiho +3 more
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Characterization of porcine endogenous retrovirus expression in neonatal and adult pig pancreatic islets [PDF]
, 2017 BACKGROUND: Pig islets represent an alternative to the current modes of treatment for patients with diabetes. However, the concerns over pathogen transmission including that of PERV limit their immediate, widespread usage in humans.
Akiyoshi +36 more
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Spatiotemporal variations in retrovirus-host interactions among Darwin’s finches
Nature Communications, 2022 Endogenous retroviruses (ERV) are inherited remains of retroviruses that have colonized host genomes during evolution. Here the authors observe considerable species-specific ERV variation among Darwin’s finches, reflecting historic retrovirus-host ...
Jason Hill +7 more
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Amplification of simian retroviral sequences from human recipients of baboon liver transplants [PDF]
, 1998 Investigations into the use of baboons as organ donors for human transplant recipients, a procedure called xenotransplantation, have raised the specter of transmitting baboon viruses to humans and possibly establishing new human infectious diseases ...
Anonymous +12 more
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Endogenous Retroviruses in Domestic Animals [PDF]
Current Genomics, 2014 Endogenous retroviruses (ERVs) are genomic elements that are present in a wide range of vertebrates. Although the study of ERVs has been carried out mainly in humans and model organisms, recently, domestic animals have become important, and some species have begun to be analyzed to gain further insight into ERVs.
García Etxebarria, Koldo +2 more
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Human Endogenous Retroviruses in Glioblastoma Multiforme
Microorganisms, 2021 Glioblastoma multiforme (GBM) is the most aggressive and deadly brain tumor. It is primarily diagnosed in the elderly and has a 5-year survival rate of less than 6% even with the most aggressive therapies.
Zihao Yuan +6 more
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The baboon endogenous virus genome. II. Provirus sequence variations in baboon cell DNA [PDF]
, 1980 Restriction analysis of the approximately 100 integrated baboon endogenous virus (BaEV) proviruses in baboon cells and tissues has revealed two major sequence variations, both in the gag gene region of the genome.
Cohen, Maurice +5 more
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Endogenous retroviruses and human evolution [PDF]
Comparative and Functional Genomics, 2002 AbstractHumans share about 99% of their genomic DNA with chimpanzees and bonobos; thus, the differences between these species are unlikely to be in gene content but could be caused by inherited changes in regulatory systems. Endogenous retroviruses (ERVs) comprise ∼ 5% of the human genome.
Khodosevich, Konstantin +2 more
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When should precaution prevail? : interests in (public) health, the risk of harm and xenotransplantation. [PDF]
, 2010 Xenotransplantation is an example of a developing biotechnology which highlights three differing interests in the health of the public; a specific interest in enhancing the health of individuals who require a particular procedure or treatment, a wider ...
Fovargue, Sara, Ost, Suzanne
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