Results 11 to 20 of about 52,210 (255)

Degradation and remobilization of endogenous retroviruses by recombination during the earliest stages of a germ-line invasion [PDF]

, 2018
Endogenous retroviruses (ERVs) are proviral sequences that result from colonization of the host germ line by exogenous retroviruses. The majority of ERVs represent defective retroviral copies.
Alquezar-Planas, David E., Dayaram, Anisha, Greenwood, Alex D., Hobbs, Matthew, Ishida, Yasuko, Jones, Kiersten, Löber, Ulrike, Mayer, Jens, Meers, Joanne, Tsangaras, Kyriakos   +9 more
core   +3 more sources

Endogenous Retroviruses in Nervous System Disorders [PDF]

Pharmaceuticals, 2021
Human endogenous retroviruses (HERV) have been implicated in the pathogenesis of several nervous system disorders including multiple sclerosis and amyotrophic lateral sclerosis.
Victoria Gröger, Alexander Emmer, Martin S. Staege, Holger Cynis   +3 more
doaj   +4 more sources

Human endogenous retroviruses and cancer

Cancer Biology & Medicine, 2016
Human endogenous retroviruses (HERVs) are retroviruses that infected human genome millions of years ago and have persisted throughout human evolution.
María Gonzalez-Cao, Paola Iduma, Niki Karachaliou, Mariacarmela Santarpia, Julià Blanco, Rafael Rosell   +5 more
doaj   +4 more sources

Antibodies against endogenous retroviruses. [PDF]

Immunol Rev
SummaryThe human genome harbors hundreds of thousands of integrations of ancient retroviruses, amassed over millions of years of evolution. To reduce further amplification in the genome, the host prevents transcription of these now endogenous retroviruses (ERVs) through epigenetic repression and, with evolutionary time, ERVs are incapacitated by ...
Chisca M, Larouche JD, Xing Q, Kassiotis G.   +3 more
europepmc   +3 more sources

Endogenous retroviruses are dysregulated in ALS [PDF]

iScience
Summary: Amyotrophic lateral sclerosis (ALS) is a universally fatal neurodegenerative disease with no cure. Human endogenous retroviruses (HERVs) have been implicated in its pathogenesis but their relevance to ALS is not fully understood.
Nicholas Pasternack, Tara Doucet-O’Hare, Kory Johnson, Ole Paulsen, Avindra Nath   +4 more
doaj   +2 more sources

Human endogenous retroviruses and ageing [PDF]

Immunity & Ageing, 2021
Mikko Hurme, Graham Pawelec
doaj   +3 more sources

Human endogenous retroviruses and exogenous viral infections [PDF]

Frontiers in Cellular and Infection Microbiology
The human genome harbors many endogenous retroviral elements, known as human endogenous retroviruses (HERVs), which have been integrated into the genome during evolution due to infections by exogenous retroviruses.
Chenxuan Bao, Qing Gao, Huayuan Xiang, Yuxuan Shen, Qiaoqiao Chen, Qianqian Gao, Yuanfei Cao, Mengyu Zhang, Wenyuan He, Lingxiang Mao   +9 more
doaj   +2 more sources

An Aberrant Resurgence of Endogenous Retroviruses Prompts Myocarditis and Heart Failure. [PDF]

Circulation
Xiong J, Zhang S, Geng Z, Lin J, Cheng K, Hu H, Wang Y, Liu X, Sheng Y, Yang P, Li Y, Wu S, Cheng X, Li Y, Sun A, Chen AF, Wang D, Chen C, Zhang Y, Wu G, Zeng C, Guo X, Hou X, Li R, Feng Y, Zhu D, Sun K, Zhang B.   +27 more
europepmc   +3 more sources

Therapeutic potential of the human endogenous retroviral envelope protein HEMO: a pan‐cancer analysis

Molecular Oncology, 2022
Human endogenous retroviruses represent approximately 8% of our genome. Most of these sequences are defective except for a few genes such as the ancestral retroviral HEMO envelope gene (Human Endogenous MER34 ORF), recently characterized by our group. In
Amélie Kasperek, Anthony Béguin, Olivia Bawa, Kévin De Azevedo, Bastien Job, Christophe Massard, Jean‐Yves Scoazec, Thierry Heidmann, Odile Heidmann   +8 more
doaj   +1 more source

Endogenous retroviruses [PDF]

Current Biology, 2015
Endogenous retroviruses are integral features of vertebrate genomes. Here, Hayward and Katzourakis offer a glimpse into the fascinating world of these mysterious partners in our evolution.
Hayward, Alexander, Katzourakis, Aris
openaire   +2 more sources