Results 21 to 30 of about 445,067 (194)
Molecular Oncology, 2022 Human endogenous retroviruses represent approximately 8% of our genome. Most of these sequences are defective except for a few genes such as the ancestral retroviral HEMO envelope gene (Human Endogenous MER34 ORF), recently characterized by our group. In
Amélie Kasperek +8 more
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Current Biology, 2015 Endogenous retroviruses are integral features of vertebrate genomes. Here, Hayward and Katzourakis offer a glimpse into the fascinating world of these mysterious partners in our evolution.
Hayward, Alexander, Katzourakis, Aris
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The detection and role of human endogenous retroviruses in multiple sclerosis and other neurological diseases [PDF]
, 2009 A thesis submitted in partial fulfilment of the requirements of the University of Wolverhampton for the degree of Master of PhilosophyHuman endogenous retroviruses (HERVs) are estimated to form approximately 5% of the human genome.
Smith, Richard G.
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npj Vaccines, 2021 Replicative vectors derived from live-attenuated measles virus (MV) carrying additional non-measles vaccine antigens have long demonstrated safety and immunogenicity in humans despite pre-existing immunity to measles.
Patrycja Nzounza +14 more
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Evolutionary analysis of endogenous intronic retroviruses in primates reveals an enrichment in transcription binding sites associated with key regulatory processes [PDF]
PeerJ, 2022 Background Endogenous retroviruses (ERVs) are the result of the integration of retroviruses into host DNA following germline infection. Endogenous retroviruses are made up of three main genes: gag, pol, and env, each of which encodes viral proteins that ...
Melissa Calero-Layana +4 more
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Endogenous retroviruses and human evolution [PDF]
Comparative and Functional Genomics, 2002 AbstractHumans share about 99% of their genomic DNA with chimpanzees and bonobos; thus, the differences between these species are unlikely to be in gene content but could be caused by inherited changes in regulatory systems. Endogenous retroviruses (ERVs) comprise ∼ 5% of the human genome.
Khodosevich, Konstantin +2 more
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Induced prion protein controls immune-activated retroviruses in the mouse spleen. [PDF]
PLoS ONE, 2007 The prion protein (PrP) is crucially involved in transmissible spongiform encephalopathies (TSE), but neither its exact role in disease nor its physiological function are known.
Marius Lötscher +9 more
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Biology, 2020 Two human endogenous retroviruses of the HERV-W family can act as cofactors triggering multiple sclerosis (MS): MS-associated retrovirus (MSRV) and ERVWE1.
Vera R. Lezhnyova +5 more
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Endogenous Retroviruses in Domestic Animals [PDF]
Current Genomics, 2014 Endogenous retroviruses (ERVs) are genomic elements that are present in a wide range of vertebrates. Although the study of ERVs has been carried out mainly in humans and model organisms, recently, domestic animals have become important, and some species have begun to be analyzed to gain further insight into ERVs.
García Etxebarria, Koldo +2 more
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Nature Communications, 2023 The contribution of transposable elements and endogenous retroviruses to renal fibroinflammation is currently unknown. Here, the authors comprehensively profile the expression of transposable elements and endogenous retroviruses (ERVs) in kidneys of ...
Poonam Dhillon +9 more
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