Results 141 to 150 of about 603,777 (298)

Persistence pays: how viruses promote host group survival. [PDF]

, 2009
Recently, we have realized that viruses numerically dominate all life. Although viruses are known to affect host survival in populations, this has not been previously evaluated in the context of host group selection.
Villarreal, Luis P
core  

Xenotransplantation at a Crossroads: Breakthroughs, Challenges, and the Path Forward

Organ Medicine, EarlyView.
Xiaoyu Gan, Jizhang Yu, Jie Wu, Junjie Zong   +3 more
wiley   +1 more source

Harnessing viral footprints in circulating free DNA (cfDNA) for early cancer detection: A focus on liquid‐biopsy‐based screening

International Journal of Cancer, Volume 158, Issue 3, Page 511-526, 1 February 2026.
Abstract Viral infections play a significant role in cancer development, making detecting viral signatures a promising approach for early cancer diagnosis. Circulating free DNA (cfDNA), released into the bloodstream by tumors and other cells, has emerged as a powerful biomarker for non‐invasive cancer screening.
Richard Donkor Amponsah, Emmanuel Addai Gyabaah, Moro Amidu, Zhao Cheng, Fazlur Rahman Talukdar   +4 more
wiley   +1 more source

Placental Development and Endogenous Retroviruses

Uirusu, 2016
A placenta as we know now is a relatively new invention in mammals. Data accumulated indicates that a major cell type of the placenta is trophoblast, in which elevated expression of genes derived from various endogenous retroviruses (ERVs) as well as LTR retrotransposons is seen.
Kazuhiko, Imakawa, So, Nakagawa, Kazuya, Kusama   +2 more
openaire   +3 more sources

Endogenous retroviruses and TDP-43 proteinopathy form a sustaining feedback driving intercellular spread of Drosophila neurodegeneration [PDF]

, 2023
Yung‐Heng Chang, Josh Dubnau
openalex   +1 more source

A Novel Human Cellular System for Studying Normal Aging and for Anti‐Aging Discovery

Aging Cell, Volume 25, Issue 2, February 2026.
This study introduces a human cellular aging model using placental trophoblasts (hTSC‐STBs) that mimics key aging features like senescence and genomic instability. It aligns with human tissue aging and responds to anti‐aging treatments, offering a scalable platform to screen potential therapies and bridge lab findings to clinical applications ...
Zhen Feng, Cheuk Shuen Li, Haifeng Fu, Wenxin Jiang, Weiyu Zhang, Yingzhang Huang, Yunying Huang, Timothy Theodore Ka Ki Tam, Yang Li, Fang Liu, Liming Lu, Yin Lau Lee, William Shu Biu Yeung, Gordon Dougan, Pentao Liu   +14 more
wiley   +1 more source

Negative selection by an endogenous retrovirus promotes a higher-avidity CD4+ T cell response to retroviral infection.

PLoS Pathogens, 2012
Effective T cell responses can decisively influence the outcome of retroviral infection. However, what constitutes protective T cell responses or determines the ability of the host to mount such responses is incompletely understood.
George R Young, Mickaël J-Y Ploquin, Urszula Eksmond, Munisch Wadwa, Jonathan P Stoye, George Kassiotis   +5 more
doaj   +1 more source

Pedigree reconstruction for cosexual species using simulated annealing: case study of oil palm (Elaeis guineensis) : P-124 [PDF]

, 2012
The approach of Fernandez and Toro (2006) to reconstruct pedigrees from molecular data of contemporaneous individuals using a simulated annealing algorithm was extended to hermaphroditic and monoecious species.
Bouvet, Jean-Marc, Cros, David, Fernandez, Jesus, Sanchez, Leopoldo   +3 more
core  

Single-cell transcriptomics of resected human traumatic brain injury tissues reveals acute activation of endogenous retroviruses in oligodendroglia

, 2022
Raquel Garza, Yogita Sharma, Diahann A. M. Atacho, Arun Thiruvalluvan, Sami Abu Hamdeh, Marie E. Jönsson, Vivien Horváth, Anita Adami, Martin Ingelsson, Patric Jern, Molly Hammell, Elisabet Englund, Agnete Kirkeby, Johan Jakobsson, Niklas Marklund   +14 more
openalex   +1 more source

Lysophosphatidic Acid Synergizes With 1,25‐Dihydroxyvitamin D to Promote Fibroblast Growth Factor‐23 Synthesis via MAPK Signaling and Induction of the IL12A Gene

The FASEB Journal, Volume 40, Issue 1, 15 January 2026.
Ay et al. investigated the cellular mechanisms behind the role of lysophosphatidic acid (LPA) in FGF23 production. They revealed that LPA cooperates with 1,25‐dihydroxyvitamin D (1,25D), that is, the bioactive form of vitamin D known to stimulate FGF23 synthesis. This synergy entails MAPK signaling and the induction of the gene encoding the interleukin‐
Birol Ay, Sajin Marcus Cyr, Yorihiro Iwasaki, Elizabeth Hill, Eugene P. Rhee, Nevil J. Singh, Petra Simic, Murat Bastepe   +7 more
wiley   +1 more source