Results 71 to 80 of about 233,563 (251)

Clinical outcomes from a randomised comparison of Microwave Endometrial Ablation with Thermal Balloon endometrial ablation for the treatment of heavy menstrual bleeding [PDF]

, 2009
The definitive version is available at www3.interscience.wiley.comPeer ...
Campbell, MK, Sambrook, A M, Cook, JA, Cooper, K G, Campbell, M K, Cook, J A, Sambrook, AM, Cooper, KG   +7 more
core   +1 more source

Genetic Ablation and Multi‐Omics Profiling Reveal CEP55 as a Key Driver of Tumorigenesis in Diverse Cancer Models

Advanced Science, EarlyView.
Genetic ablation of Cep55 in Pten‐deficient mouse models delays tumorigenesis. Integrated multi‐omics analyses (proteomics, phosphoproteomics, and spatial transcriptomics) reveal that CEP55 regulates oncogenic signaling (RAS/ERK, PI3K/AKT), integrin/FAK‐mediated adhesion, extracellular matrix (ECM) remodeling, and endocytosis.
Behnam Rashidieh, Yuanhao Yang, Amanda Louise Bain, Phillip Theron, Catharina Vosloo, Sahar Keshvari, Parinaz Ahangar, Brydie Bowden, Simon M. Tria, Ben B. Wang, Sandra Isenmann, Nicholas J. Westra van Holthe, Zherui Xiong, Hani Vu, Sowmya Sharma, Asmerom Sengal, J. Alejandro Lopez, John Finnie, Antonella Papa, Pascal H.G. Duijf, Quan Nguyen, Pirjo M. Apaja, Kum Kum Khanna   +22 more
wiley   +1 more source

B Cells are Activated via a Nanoporous Interface that Stabilizes Microvilli and Engages Mechanosensitive Ion Channels

Advanced Science, EarlyView.
B cells can be activated independently of antigen recognition via mechanical stimulation through nanoporous substrates. Exposure to such substrates induced B cell microvilli extension into the pores, intracellular Ca2+ signaling, phosphorylation of signaling proteins, and CD69 expression.
Nozie D. Aghaizu, Willi Weber, Nadine Strempel, Asya Polat, Enrico Klotzsch   +4 more
wiley   +1 more source

Study of Immunohistochemical Expression Patterns of Mismatch Repair Proteins in Endometrial Carcinoma and Endometrial Hyperplasia: An Institutional Study

Indian Journal of Medical and Paediatric Oncology
Introduction Endometrial carcinoma (EC) is the most common cancer in women (7% of all malignancies) standing fourth in prevalence. Its molecular categorization has lately gained substantial importance, because of its prognostic implications ...
Belani Vaishali Tulsidas, Kausalya Kumari Sahu, Ranjitha Rao, Sharada Rai, Chaithra G.V, Cheryl Sarah Philipose   +5 more
doaj   +1 more source

SDF‐1 Attenuates Oocyte Quality Decline During Reproductive Aging Through Autophagy‐Enhanced Stress Granule Scavenging

Advanced Science, EarlyView.
SDF‐1 levels decline significantly with maternal aging. Exogenous supplementation restores meiotic spindle morphology, chromosomal alignment, and mitochondrial function while reducing oxidative stress in aged oocytes. Mechanistically, SDF‐1 enhances autophagic activity to clear accumulated stress granules, thereby rescuing fertilization competence and ...
Rui Long, Meng Wang, Ruolin Mao, Hong Chen, Juepu Zhou, Xiangfei Wang, Zheng Yuan, Ri‐Cheng Chian, Nan Xiao, Qingsong Xi, Yimin Shu, Lei Jin, Lixia Zhu   +12 more
wiley   +1 more source

Water Vapor Endometrial Ablation for Heavy Menstrual Bleeding: 36-Month Follow-Up of a Prospective, Multicenter Pivotal Clinical Trial

International Journal of Women's Health, 2021
Nicholas Leyland,1 Micah Harris2 1Department of Obstetrics and Gynaecology, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, ON, L8S 4K1, Canada; 2AEGEA Medical, Menlo Park, CA, 94025, USACorrespondence: Micah Harris Tel +1 602-828 ...
Leyland N, Harris M
doaj  

Endometrial Stromal Nodule

, 2013
Endometrial stromal nodule (ESN) represents the benign end of the spectrum within the category of endometrial stromal tumors. Typically well-cicumscribed but not encapsulated tumors ranging in size from 0.5 to 22 (mean 7) cm.
Ayșe Sertçelik, Yasemin Yuyucu Karabulut   +1 more
core   +1 more source

The Cancer Cell Metabolic Reprogramming Remodels the Tumor Microenvironment: Molecular Mechanisms and Therapeutic Strategies

Advanced Science, EarlyView.
This review elucidates how cancer cell metabolic reprogramming—across glucose, lipid, amino acid, and nucleotide pathways—remodels the tumor microenvironment to suppress anti‐tumor immunity and promote immune escape. Targeting these metabolic axes offers promising strategies to overcome immunotherapy resistance and enhance cancer treatment.
Guoqing Xiang, Zhicheng Zhou, Xue Jiang, Zhenguang Du, Yangyang Zhan, Xinli Liu   +5 more
wiley   +1 more source

Endometrial Stromal Sarcoma Presenting As Puberty Menorrhagia [PDF]

, 2005
Endometrial stromal sarcomas are rare uterine tumours usually seen in perimenopausal females. We report here a case of low grade malignant endometrial stromal sarcoma in an adolescent girl, presenting as puberty menorrhagia.
Paul Sebastian, Prabhakaran Nair, Rema, Rema Prabhakaran Nair, Sebastian, Paul   +3 more
core  

The role of Tamoxifen in endometrial cancer

, 2023
This thesis explores the relationship between tamoxifen treatment in breast cancer and the risk of developing tamoxifen-induced endometrial cancer. Tamoxifen is a selective estrogen receptor modulator, meaning it acts as an estrogen antagonist in some ...
Chetty, Prayanka
core