Results 81 to 90 of about 233,563 (251)
An Injectable ROS‐Responsive Nanozyme Hydrogel Regulates the Uterine Microenvironment to Prevent Intrauterine Adhesions
Advanced Science, EarlyView.The injectable CeTA@GPP hydrogel is administered via intrauterine injection, forming a protective barrier. In the high ROS inflammatory microenvironment of injured endometrium, boronate ester cleavage triggers responsive CeTA release and local enrichment.Peixian Cheng, Jian Song, Yuxin Li, Ming Chen, Zeshen Liang, Binyao Qiu, Xuemin Liu, Xuetao Shi, Yong Fan +8 morewiley +1 more sourceComparison of the Effects of Early Pregnancy with Human Interferon, Alpha 2 (IFNA2), on Gene Expression in Bovine Endometrium [PDF]
, 2012 Interferon tau (IFNT), a type I IFN similar to alpha IFNs (IFNA), is the pregnancy recognition signal produced by the ruminant conceptus. To elucidate specific effects of bovine IFNT and of other conceptus-derived factors, endometrial gene expression ...Sax, Gerhard, Minten, Megan, Winter, Gerhard, Büttner, Mathias, Reichenbach, Horst-Dieter, Wolf, Eckhard, Meyer, Heinrich H. D., Bauersachs, Stefan, Reichenbach, Myriam, Spencer, Thomas E., Ulbrich, Susanne E. +10 morecore +1 more sourceFOXP1 Knockdown Reprograms Th9 CAR‐T Cells to Overcome Antigen Escape
Advanced Science, EarlyView.FOXP1 knockdown enhances Th9 CAR‐T cell function by promoting IL‐9 production, effector activation, and reduced exhaustion. Reprogrammed Th9 CAR‐T cells strengthen direct tumor killing and activate endogenous antitumor immunity through dendritic cells and CD8+ T cells, thereby suppressing both antigen‐positive and antigen‐loss tumor growth and ...Yihan Zhu, Xingwei Xie, Xiaohuan Wu, Suidong Ouyang, Yang Zhou, Kang Wen, Yutong Zhong, Yuyang Chen, Handuo Wang, Yuan Gao, Ling Jiang, Hui Li, Wenli Zhao, Abai Xu, Enguang Bi +14 morewiley +1 more sourceA Metabolic‐Epigenetic Axis of AARS1/IGF2BP3‐K280 Lactylation Sustains Endometrial Cancer Stemness and Recurrence
Advanced Science, EarlyView.Lactate‐driven endometrial cancer relapse is mediated by enzymatic protein modification. Elevated lactate levels activate AARS1, which catalyzes K280 lactylation of IGF2BP3, therefore stabilizing HMGA2 mRNA and promoting tumor stemness and recurrence.Peng Jiang, Yunfeng Zheng, Chenfan Tian, Yuan Tu, Xiaoxia Chang, Jiaxin Yu, Hangkun Yu, Chunxia Gong, Jie Xiong, Philip N. Baker, Yong Fu, Chao Tong +11 morewiley +1 more sourceCandidate locus analysis of the TERT-CLPTM1L cancer risk region on chromosome 5p15 identifies multiple independent variants associated with endometrial cancer risk. [PDF]
, 2014 Several studies have reported associations between multiple cancer types and single-nucleotide polymorphisms (SNPs) on chromosome 5p15, which harbours TERT and CLPTM1L, but no such association has been reported with endometrial cancer.Olson, J.E., Amant, Frederic J, Schrauwen, S., Beesley, Jonathan, Hillemanns, Peter, Attila Teoman, The GENICA Network, Couch, Fergus J, Jianjun Liu, Wentzensen, N., Scott, Rodney J., Timothy Cheng, Bolla, Manjeet K, Hein, A, Amant, F., Ruebner, M, Cheng, Timothy, Beckmann, Matthias W., The Australian National Endometrial Cancer Study Group (ANECS), Carvajal-Carmona, L G, Dieffenbach, AK, Meindl, A., Dunning, A.M., Dowdy, SC, Deborah J. Thompson, Wentzensen, Nicolas, Fiona Bruinsma, Jenny Chang-Claude, Ferguson, K, Per Hall, Giles, Graham G., Salvesen, Helga, Lambrechts, D., Salvesen, H.B., Hopper, JL, Coenegrachts, L., Maggie Gorman, Ekici, Arif B., Runnebaum, I., Hopper, J L, Pharoah, Paul D.P., Hein, Alexander, Czene, Kamila, Johnson, N., Spurdle, Amanda B., Spurdle, AB, Marme, Frederik, Otton, G., National Study of Endometrial Cancer Genetics Group (NSECG),,, Melissa C. Southey, Liu, J, Douglas F. Easton, Healey, C.S., Teoman, A., Ruebner, M., Bolla, MK, Easton, D F, Werner, H.M.J., Healey, C S, Liu, Jianjun, Qin Wang, Ahmed, S., Kimberley Howarth, Painter, JN, Cheng, T, Pooley, K, O'Mara, Tracy A, Kristensen, Vessela, Marme, F, Njolstad, Tormund S., Teoman, Attila, O’Mara, T.A, Michailidou, Kyriaki, Australian Ovarian Cancer Study (AOCS), Lindblom, A., Cunningham, Julie M., Spurdle, Amanda B, Painter, Jodie N., Scott, R.J., Scott, Rodney J, Gorman, M., Painter, J., Bolla, M.K., Johnson, N, Hodgson, Shirley, Amant, F, Jones, Angela, Børresen-Dale, Anne-Lise, Felicity A. Lose, Shirley Hodgson, Dieffenbach, A K, Cunningham, JM, Nicholas Orr, Bolla, Manjeet, Njølstad, Tormund Salvesen, Renner, S P, Olson, Janet E, Pharoah, P D P, Thompson, Deborah J., Kyriaki Michailidou, et al., Painter, J.N, Lose, Felicity A, Hopper, J.L., Dennis, J, Cox, A, Werner, H M J, Alexander Hein, Salvesen, H B, Hillemanns, P., Bolla, M K, Nichola Johnson, Borresen-Dale, Anne-Lise, Depreeuw, J, Brauch, H, Pharoah, P.D.P., Pooley, K., Moisse, M., Cunningham, Julie, Trovik, Jone, Southey, Melissa Caroline, Cox, Angela, Trovik, J, Goode, Ellen L., Lose, F.A., Depreeuw, Jeroen, Ferguson, Kaltin, Goode, E.L., Tony Proietto, O'Mara, Tracy A., Renner, SP, Ekici, Arif B, Weber, RP, Dürst, Matthias, Mints, M, Shah, Mitul, AOCS, Gorman, M, Jonathan Beesley, Werner, Henrica MJ, Matthias Dürst, The GENICA Network,, Tomlinson, I, Stefan P. Renner, Peto, Julian, Fridley, B.L., Johnson, Nichola, Olson, J E, Boris Winterhoff, Giles, GG, Hermann Brenner, Julie M. Cunningham, Schrauwen, S, Easton, Douglas F, Martin, L., Wentzensen, Nicholas, Tham, E, Giles, G G, Zhihua Chen, Southey, M C, Alison M. Dunning, Wang, Q., Thompson, DJ, Proietto, T., GENICA Network, Diether Lambrechts, Hall, Per, Lindblom, Annika, Cheng, T., Njolstad, Tormund S, Annika Lindblom, Ian Tomlinson, Howarth, Kimberley, Brenner, H., Jeroen Depreeuw, O’Mara, Tracy A, Couch, FJ, Beckmann, M W, O’Mara, T A, Fasching, PA, Meindl, A, Proietto, Anthony, Winterhoff, Boris, Brauch, H., Miriam Mints, Burwinkel, B., Lambrechts, Diether, Chen, Zhihua, Bruinsma, F., John L. Hopper, Lose, F., Hodgson, S., Orr, N, Tomlinson, Ian, Lose, FA, Anja Rudolph, Giles, Graham G, Tyrer, J., Southey, Melissa C., Renner, S.P., Tormund S. Njolstad, Beckmann, MW, Beesley, J, Tyrer, JP, Weber, Rachel Palmieri, Lynn Martin, Brenner, H, Ingo Runnebaum, Winterhoff, B., Dowdy, Sean C., Easton, Douglas F., Ashton, Katie, Fasching, P A, Orr, Nicholas, Wentzensen, N, Healey, Catherine S, Ashton, K, Couch, Fergus J., Duerst, M., Frederic Amant, Dowdy, Sean C, Fasching, Peter A., Giles, G.G., Barbara Burwinkel, Ekici, A B, Tham, E., Salvesen, HB, Runnebaum, Ingo B, Dörk, Thilo, Peto, J., Couch, F.J., O Mara, T., Stefanie Schrauwen, Angela Cox, Hillemanns, P, Chen, Z, Dunning, Alison M., Arif B. Ekici, Renner, Stefan P, Olson, Janet E., Kamila Czene, Matthieu Moisse, Pharoah, Paul D. P., Rudolph, A., Michailidou, K, Hiltrud Brauch, Emma Tham, Chang-Claude, J., Spurdle, A B, Painter, J.N.., The Australian National Endometrial Cancer Study Group (ANECS),, Ahmed, Shahana, Katie Ashton, Tomlinson, Ian P, Dieffenbach, A.K., Couch, F J, Rachel Palmieri Weber, Kristensen, Vessela N., Dörk, T, Carvajal-Carmona, L.G., Lose, Felicity, Jonathan P. Tyrer, Otton, Geoffrey, Goode, EL, Hein, A., Dunning, A M, Spurdle, A.B., Kristensen, V N, Doerk, T., Lieve Coenegrachts, Hall, P, Hopper, John L., Werner, HM, Australian Ovarian Cancer Study (AOCS),, RENDOCAS,, Carvajal-Carmona, Luis G, Liu, J., Dowdy, S C, Tomlinson, I., Frederik Marme, Proietto, T, Rudolph, A, Swerdlow, A.J., Salvesen, Helga B., Catherine S. Healey, null null, Dieffenbach, Aida Karina, Wang, Qin, Tyrer, J.P., Janet E. Olson, Ruebner, Matthias, Geoffrey Otton, Aida K. Dieffenbach, Beckmann, Matthias W, Fasching, P.A., National Study of Endometrial Cancer Genetics Group (NSECG),, Michailidou, K., Ekici, A.B., Wang, Q, Jone Trovik, Dunning, Alison M, Marme, F., Goode, E L, Ferguson, K., Ahmed, S, Mints, Miriam, Dunning, AM, Bolla, Manjeet K., Czene, K, Burwinkel, B, Amant, Frederic, Goode, Ellen L, Easton, DF, Otton, G, Borresen-Dale, A.-L., Kaltin Ferguson, RENDOCAS, Pooley, Karen, Trovik, J., Dennis, Joe, Swerdlow, Anthony J., Fridley, BL, Orr, N., Rudolph, Anja, Winterhoff, B, Teoman, A, O'Mara, T.A., Ellen L. Goode, Luis G. Carvajal-Carmona, Angela Jones, Mints, M., Fridley, Brooke, Pharoah, Paul DP, Southey, M.C., Renner, Stefan P., Tham, Emma, Chang-Claude, J, Tyrer, Jonathan P, Lambrechts, Dieter, Swerdlow, A J, Bruinsma, F, Olson, JE, Moisse, M, Werner, Henrica Maria Johanna, Thilo Dörk, Li, J, Coenegrachts, Lieve, Ashton, K., Hall, P., O’Mara, TA, Weber, R.P., Karen Pooley, Carvajal-Carmona, LG, Matthias Ruebner, Ekici, AB, Carvajal-Carmona, L.G, Dürst, M, Joe Dennis, Moisse, Matthieu, Network, GENICA, Dennis, J., Peto, J, Brauch, Hiltrud, Painter, J N, Rodney J. Scott, Dieffenbach, Aida K., Lambrechts, D, Howarth, K, Amanda B. Spurdle, Paul D. P. Pharoah, Julian Peto, Dieffenbach, Aida K, O'Mara, TA, Tyrer, J P, Werner, Henrica M.J., Cunningham, J.M., Scott, R J, Brooke L. Fridley, Jones, A., Wersaell, O., Børresen-Dale, A L, Beesley, J., Beckmann, M.W., Manjeet K. Bolla, Henrica M. J. Werner, Nicholas Wentzensen, Dowdy, S.C., Anne-Lise Børresen-Dale, Salvesen, Helga B, Werner, Henrica M. J., Coenegrachts, L, Hopper, John L, Anthony J. Swerdlow, Lindblom, A, Meindl, Alfons, Thompson, Deborah J, Li, J., Wersäll, O, Carvajal-Carmona, L., Cunningham, J M, Swerdlow, AJ, Salvesen, Helga Birgitte, Southey, MC, Fridley, Brooke L., Healey, C., Ofra Wersäll, Fergus J. Couch, Schrauwen, Stefanie, Howarth, K., Runnebaum, Ingo, Healey, Catherine S., Carvajal-Carmona, Luis G., Scott, RJ, Børresen-Dale, AL, Pharoah, Paul D P, Li, Jingmei, Graham G. Giles, Peter A. Fasching, Czene, K., Tyrer, Jonathan P., Pharoah, PD, National Study of Endometrial Cancer Genetics Group (NSECG), Hodgson, S, Chen, Z., Martin, L, Kristensen, Vessela N, Shah, M., ANECS, Jodie N. Painter, Healey, CS, Shahana Ahmed, Mitul Shah, Burwinkel, Barbara, Painter, Jodie N, Southey, Melissa C, Fasching, Peter, Pharoah, PDP, Tracy A. O’Mara, Vessela N. Kristensen, Kristensen, VN, Matthias W. Beckmann, Pooley, Karen A, Gorman, Maggie, Alfons Meindl, Beckmann, Matthias, Fridley, Brooke L, Jones, A, Cox, A., Runnebaum, I, Lose, Felicity A., Cunningham, Julie M, Werner, HMJ, Sean C. Dowdy, Depreeuw, J., Helga B. Salvesen, Peter Hillemanns, Jingmei Li, Weber, R P, Njolstad, T.S., Thompson, D J, Proietto, Tony, Easton, D.F., Chang-Claude, Jenny, Australian National Endometrial Cancer Study Group (ANECS), Thompson, D.J., Shah, M, Swerdlow, Anthony J, Fasching, Peter A, Bruinsma, Fiona, Wersäll, Ofra, Brenner, Hermann, Martin, Lynn, Fridley, B L, Njolstad, TS, Kristensen, V.N., Njolstad, T S, NSECG, Doerk, Thilo, Duerst, Matthias, Carvajal-Carmona, Luis G;O'Mara, Tracy A;Painter, Jodie N;Lose, Felicity A;Dennis, Joe;Michailidou, Kyriaki;Tyrer, Jonathan P;Ahmed, Shahana;Ferguson, Kaltin;Healey, Catherine S;Pooley, Karen;Beesley, Jonathan;Cheng, Timothy;Jones, Angela;Howarth, Kimberley;Martin, Lynn;Gorman, Maggie;Hodgson, Shirley;Wentzensen, Nicholas;Fasching, Peter A;Hein, Alexander;Beckmann, Matthias W;Renner, Stefan P;Dörk, Thilo;Hillemanns, Peter;Dürst, Matthias;Runnebaum, Ingo;Lambrechts, Diether;Coenegrachts, Lieve;Schrauwen, Stefanie;Amant, Frederic;Winterhoff, Boris;Dowdy, Sean C;Goode, Ellen L;Teoman, Attila;Salvesen, Helga B;Trovik, Jone;Njolstad, Tormund S;Werner, Henrica M J;Scott, Rodney J;Ashton, Katie;Proietto, Tony;Otton, Geoffrey;Wersäll, Ofra;Mints, Miriam;Tham, Emma;Hall, Per;Czene, Kamila;Liu, Jianjun;Li, Jingmei;Hopper, John L;Southey, Melissa C;Ekici, Arif B;Ruebner, Matthias;Johnson, Nichola;Peto, Julian;Burwinkel, Barbara;Marme, Frederik;Brenner, Hermann;Dieffenbach, Aida K;Meindl, Alfons;Brauch, Hiltrud;Lindblom, +479 morecore +2 more sourcesSAV1 in Cooperation With FKBP52 Participates in Implantation
Advanced Science, EarlyView.The MST‐SAV1 complex modulates FKBP52 phosphorylation to fine‐tune PR activity, ensuring timely uterine transition to receptivity under estrogen signaling for implantation. Stromal SAV1 scaffolds MST1/2‐mediated FKBP52 phosphorylation via noncanonical Hippo to promote PR activity.Yuhan Shao, Yafang Lu, Zhaoyu Jia, Junxiang Ren, Ziyi Ge, Xinyu Liu, Hui Zhao, Zi‐Jiang Chen, Junhao Yan, Wei Wang, Jia Yuan +10 morewiley +1 more source
