A Bayesian Nonparametric Model for Zero-Inflated Outcomes: Prediction, Clustering, and Causal Estimation [PDF]
Researchers are often interested in predicting outcomes, conducting clustering analysis to detect distinct subgroups of their data, or computing causal treatment effects. Pathological data distributions that exhibit skewness and zero-inflation complicate these tasks - requiring highly flexible, data-adaptive modeling.
arxiv +1 more source
Post-COVID-19 Effects on Female Fertility: An In-Depth Scientific Investigation [PDF]
This study aimed to comprehensively investigate the post-COVID-19 effects on female fertility in patients with a history of severe COVID-19 infection. Data were collected from 340 patients who had previously experienced severe COVID-19 symptoms and sought medical assistance at private clinics and fertility centers in various provinces of Iraq.
arxiv
Exosome‐based nanoparticles (GC‐Exo‐CD16Ab) are designed to deliver glucocorticoids (GC) specifically to decidual CD16+ NK cells and macrophages. This targeted delivery effectively suppresses the cytotoxicity of decidual NK cells, inhibits M1 macrophage polarization, and modulates the decidual microenvironment.
Linlin Wang+17 more
wiley +1 more source
Progesterone receptors in development and metatstais of endometrial cancer [PDF]
Many women may acquire endometrial cancer during their life. The vast majority of these women will be cured because of early detection of the disease. As in most types of cancer however, the main cause of death lies in metastasis of the primary tumor ...
Hanekamp, E.E. (Eline)
core +1 more source
Linking type 2 diabetes and gynecological cancer: An introductory overview [PDF]
Type 2 diabetes (T2D) is a chronic disease with a growing prevalence and a leading cause of death in many countries. Several epidemiological studies observed an association between T2D and increased risk of many types of cancer, such as gynecologic ...
Anastasi, Emanuela+5 more
core +1 more source
Sensor technologies in cancer research for new directions in diagnosis and treatment: and exploratory analysis [PDF]
The goal of this study is an exploratory analysis concerning main sensor technologies applied in cancer research to detect new directions in diagnosis and treatments. The study focused on types of cancer having a high incidence and mortality worldwide: breast, lung, colorectal and prostate.
arxiv
The splicing factor PTBP3 promotes COX11 exon skipping, allowing gastric cancer organoids to evade cuproptosis. Antisense oligonucleotide drugs targeting PTBP3‐mediated COX11 alternative splicing, in combination with copper ionophores, promote cuproptosis in organoids, thereby providing a therapeutic approach for gastric cancer peritoneal metastasis ...
Yajing Zhou+11 more
wiley +1 more source
Role of metabolic syndrome and lifestyle factors in endometrial cancer risk and prevention
Introduction: The incidence of endometrial cancer, the sixth most common cancer among women, has been rising, especially in developed countries, possibly due to the obesity and diabetes pandemic.
Anita Kwiatkowska+9 more
doaj +1 more source
Cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy for patients with peritoneal metastases from endometrial cancer [PDF]
Background: More information is needed for selection of patients with peritoneal metastases from endometrial cancer (EC) to undergo cytoreductive surgery (CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC). Methods: This study analyzed clinical,
Biacchi, Daniele+9 more
core +1 more source
Engineered Tissue Models to Decode Host–Microbiota Interactions
Host–Microbiota interactions in the human body. Created in BioRender. Ghezzi, C. (2025) https://BioRender.com/ihivskg. Abstract A mutualistic co‐evolution exists between the host and its associated microbiota in the human body. Bacteria establish ecological niches in various tissues of the body, locally influencing their physiology and functions, but ...
Miryam Adelfio+5 more
wiley +1 more source