Results 91 to 100 of about 210,178 (195)

The role of extracellular vesicles in the communication between endometrial cancer cells and tumour-associated macrophages: a review

Journal of Cancer Research and Clinical Oncology
Endometrial cancer is a significant threat to the health of women worldwide. Extracellular vesicles are essential for the proliferation, migration, and invasion of cancer cells, whereas tumour-associated macrophages (TAMs) are key regulators of cancer ...
Feng Li, Wei Shi
doaj   +1 more source

MTFR2 promotes endometrial carcinoma cell proliferation and growth via the miR-132-3p/PI3K/Akt signaling pathway

Frontiers in Medicine
ObjectiveUnderstanding the mechanisms underlying endometrial cancer progression is crucial for the development of effective targeted therapies. In this study, we investigated the role of MTFR2 in endometrial cancer cell.MethodsThe expression of MTFR2 in ...
Zhijun Niu, Yue Zhang, Yishan Wang, Dongxia Liu, Junmin Wang, Tingting Shi, Xia Xu, Lei Li   +7 more
doaj   +1 more source

EMP2 regulates angiogenesis in endometrial cancer cells through induction of VEGF. [PDF]

, 2013
Understanding tumor-induced angiogenesis is a challenging problem with important consequences for the diagnosis and treatment of cancer. In this study, we define a novel function for epithelial membrane protein-2 (EMP2) in the control of angiogenesis ...
Braun, J, Chan, A, Dhawan, P, Fu, M, Goodglick, L, Gordon, LK, Kiyohara, M, Wadehra, M   +7 more
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Targeting the splicing factor SNRPB inhibits endometrial cancer progression by retaining the POLD1 intron

Experimental and Molecular Medicine
Dysregulated alternative splicing has been closely linked to the initiation and progression of tumors. Nevertheless, the precise molecular mechanisms through which splicing factors regulate endometrial cancer progression are still not fully understood ...
Yingwei Li, Zhongshao Chen, Huimin Xiao, Yanling Liu, Chen Zhao, Ning Yang, Cunzhong Yuan, Shi Yan, Peng Li   +8 more
doaj   +1 more source

Cold atmospheric plasma drives USP49/HDAC3 axis mediated ferroptosis as a novel therapeutic strategy in endometrial cancer via reinforcing lactylation dependent p53 expression

Journal of Translational Medicine
Background Endometrial cancer ranks among the most common gynecological cancers, with increasing rates of incidence and death. Cold atmospheric plasma (CAP) has become a promising novel therapeutic approach for cancer treatment.
Jinlin Liu, Yang Li, Ruonan Ma, Youming Chen, Jinyang Wang, Lindong Zhang, Baojin Wang, Zidi Zhang, Lili Huang, Hongyan Zhang, Junhu Wan, Hongyang Liu   +11 more
doaj   +1 more source

The prognostic role of mitosis index, stage and grade of endometrial cancer in Dr. Soetomo General Academic Hospital Surabaya, Indonesia, in 2018-2020

Majalah Obstetri dan Ginekologi
HIGHLIGHTS 1. Mitotic index and grade are prognostic factors for endometrial cancer, but both are independent. 2. Stage and mitotic index associated with cell proliferation affect the prognosis of endometrial cancer.
Farida Umi Choviva, Willy Sandhika, Pungky Mulawardhana   +2 more
doaj   +1 more source

Red cell distribution width and mean platelet volume detection in patients with endometrial cancer and endometrial hyperplasia

Health Science Reports
Background Endometrial cancer is the most common malignancy in women in developed countries, and its incidence is increasing annually. Due to the availability and cost‐effectiveness of serum markers of red cell distribution width (RDW), and mean platelet
Zahra Rafiei Sorouri, Roya Kabodmehri, Forozan Milani, Parmoon Parvari   +3 more
doaj   +1 more source

Mechanism of regulation of KIF23 on endometrial cancer cell growth and apoptosis

Discover Oncology
Objective The global incidence of endometrial cancer, a malignant tumor in females, is on the rise. It is one of the most common gynecological cancers. Early-stage endometrial cancers can often be treated successfully with uterine extirpation.
Ruiying Zhuang, Haiyan Liu
doaj   +1 more source

Does immunotherapy hold great promise in endometrial cancer care? [PDF]

Front Immunol
Braszka M, Chowaniec H, Borowczyk M, Dwojak E, Stępień M, Ślubowska A, Mielczarek M, Markiewicz H, Ałtyn R, Zieliński P, Czerniak J, Adamczak O, Kluk A, Dworacki G, Dobosz P.   +14 more
europepmc   +1 more source

A critical structured review of economic evaluations of interventions for the prevention and treatment of osteoporosis [PDF]

Osteoporosis is a major cause of morbidity, mortality and resource cost amongst the elderly population. Hip fracture is the most serious of the osteoporotic fractures, with approximately 10-20% of patients dying within six months of sustaining a fracture.
Bernie O'Brien, David Torgerson, Mark Sculpher, Ron Goeree   +3 more
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