Results 101 to 110 of about 234,996 (348)

Role of metabolic syndrome and lifestyle factors in endometrial cancer risk and prevention

open access: yesQuality in Sport
Introduction: The incidence of endometrial cancer, the sixth most common cancer among women, has been rising, especially in developed countries, possibly due to the obesity and diabetes pandemic.
Anita Kwiatkowska   +9 more
doaj   +1 more source

Hormone replacement therapy [PDF]

open access: yes, 2012
Martha Hickey, Jane Elliott, Sonia Louise ...
Davison, S., Elliott, C., Hickey, M.
core   +2 more sources

Tumor Intrinsic METTL5 Modulates ATF4 Translation to Prevent T Cell‐Induced Ferroptosis in Ovarian Cancer

open access: yesAdvanced Science, EarlyView.
An integrative analysis combining in vitro genome‐wide immune screens, in vivo ICB screens, and clinical data mining identifies METTL5 as a key tumor‐intrinsic immune factor. Mechanistic studies further reveal the importance of the METTL5‐ATF4‐SLC7A11/SLC3A2‐ferroptosis axis in modulating antitumor immune responses. These findings highlight METTL5 as a
Jiakai Hou   +30 more
wiley   +1 more source

Which is the most accurate diagnostic procedure in Tamoxifen treated breast cancer patients [PDF]

open access: yes, 2018
Purpose: The aim of this study was to evaluate the diagnostic accuracy of bi-dimensional (2D) and three-dimensional (3D) transvaginal ultrasound (TVUS), hysterosonography (HSSG) and hysteroscopy in the detection of endometrial pathology in women treated ...
De Santis, A.   +8 more
core  

Application des recommandations dans la prise en charge du cancer de l’endomètre en pratique clinique. Étude rétrospective bretonne

open access: yes, 2016
National audienceObjective - To assess the use of French Cancer Institute recommendations for the diagnosis and treatment of endometrial cancer. Methods - Retrospective observational study involving 137 patients with endometrial cancer between 2011 and ...
Body, N.   +10 more
core   +2 more sources

Pancancer analysis of DNA methylation-driven genes using MethylMix. [PDF]

open access: yes, 2015
Aberrant DNA methylation is an important mechanism that contributes to oncogenesis. Yet, few algorithms exist that exploit this vast dataset to identify hypo- and hypermethylated genes in cancer.
Gevaert, Olivier   +2 more
core   +2 more sources

ggalign: Bridging the Grammar of Graphics and Biological Multilayered Complexity

open access: yesAdvanced Science, EarlyView.
The ggalign package provides a comprehensive framework for composable visualization built on top of ggplot2. Its primary purpose is to enable the construction of complex multi‐plot layouts with consistent observation alignment across plots, particularly for high‐dimensional data contexts such as genomics, transcriptomics, and microbiome studies ...
Yun Peng   +9 more
wiley   +1 more source

Tamoxifen and Assymptomatic Endometrial Thickness [PDF]

open access: yes, 2008
Tamoxifen is a first-line agent for adjuvant treatment of estrogen-receptor positive breast cancer, and is used to reduce the risk of this condition in high-risk individuals.
Amaral, N, Fatela, A, Robalo, R
core  

Pelvic floor disorders in gynecological malignancies. An overlooked problem? [PDF]

open access: yes, 2018
Cervical, endometrial, ovarian, vulvar, and vaginal cancers affect women of a broad age spectrum. Many of these women are still sexually active when their cancer is diagnosed.
Bodean, Oana M.   +7 more
core   +3 more sources

Benchmarking Ploidy Estimation Methods for Bulk and Single‐Cell Whole Genome Sequencing

open access: yesAdvanced Science, EarlyView.
It comprehensively benchmarks computational tools for ploidy estimation from bulk and single‐cell whole‐genome sequencing data. The results highlight the strengths and limitations of each method under different conditions and identify PURPLE and SeCNV show top performance in bulk and single‐cell settings, respectively.
Yawei Song   +8 more
wiley   +1 more source

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