Results 71 to 80 of about 157,097 (332)

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

Advanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey, Sudhir Kumar Rai, Li Ma, Lauren Higa, Vedbar Khadka, Hua Yang, Youping Deng   +6 more
wiley   +1 more source

Role for growth regulation by estrogen in breast cancer 1 (GREB1) in hormone-dependent cancers [PDF]

, 2018
Sex hormones play important roles in the onset and progression of several cancers, such as breast, ovarian, and prostate cancer. Although drugs targeting sex hormone function are useful in treating cancer, tumors often develop resistance.
Cheng, Meng, Kommagani, Ramakrishna, Michalski, Stephanie   +2 more
core   +2 more sources

Diagnostic, prognostic, and predictive importance of neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), and CA125 in endometrial hyperplasia and carcinoma

Indian Journal of Pathology and Microbiology
Background: Inflammation has an important role in the progression of endometrial carcinoma. Aims: The aim of this study is to find the association between neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), and CA125 in endometrial ...
Bharti Kumari, Debaditya Haldar, Guddi R. Singh, Sweta Kumari, Sangeeta Pankaj, Rajnikant Prasad   +5 more
doaj   +1 more source

Loss of PTEN Immunoexpression in Endometrial Carcinoma: A Narrative Review [PDF]

Journal of Clinical and Diagnostic Research
Endometrial carcinoma is one of the important health issues addressed globally. Therefore, understanding the molecular pathogenesis of endometrial carcinoma for the purpose of prognostic and predictive markers remains in the centre of research.
Garima Chandrakar, Arvind Bhake
doaj   +1 more source

Nuclear Mechanotransduction Across the Metastatic Cascade: Decoding Spatiotemporal Heterogeneity in Cancer Dissemination

Advanced Science, EarlyView.
Tumor metastasis results from complex interactions between cancer cells and mechanical microenvironments. We propose a “nucleus‐centered, cross‐stage mechanical signal decoding” model, highlighting how nuclear mechanosensors interpret forces at different stages.
Linqi Song, Jingyang Liu, Xue Wang, Minpu Zhang, Changgang Sun   +4 more
wiley   +1 more source

Positive Surgical Margins in the 10 Most Common Solid Cancers. [PDF]

, 2018
A positive surgical margin (PSM) following cancer resection oftentimes necessitates adjuvant treatments and carries significant financial and prognostic implications.
Califano, Joseph A, Clary, Bryan, Cohen, Ezra EW, Kane, Christopher, Lippman, Scott M, Messer, Karen, Molinolo, Alfredo, Murphy, James D, Nguyen, Quyen T, Orosco, Ryan K, Pang, John, Sacco, Assuntina, Tapia, Viridiana J, Tringale, Kathryn R, Wallace, Anne   +14 more
core   +2 more sources

Large‐Scale Quantitative Morphometry of Platelet α‐Granules via SIM Super‐Resolution Microscopy for Cancer Liquid Biopsy

Advanced Science, EarlyView.
ABSTRACT Blood‐based liquid biopsies hold transformative potential for non‐invasive cancer management, but current approaches relying on rare circulating tumor components limit their broad clinical utility. Platelets, abundant in blood and mediating diverse cancer‐associated responses, represent a compelling yet largely unexplored alternative.
Yan Ma, Huan Deng, Zelin Liu, Simei Zhong, Liangliang Wang, Mu He, Ning Jing, Lihua Dai, Yuzhen Basang, Xiao‐Yu Hu, Changyi Zhang, Huimin Zeng, Haoren Shao, Zhe Yang, Shanshan Zhao, Xiaohai Hu, Chuanjie Zhang, Xiaowei Wu, Jing Xu, Shaoqun Zeng, Jing Yuan, Qiang Li, Ziwei Qu, Zhenya Hong, Lingjuan Chen, Hanhua Dong, Jia Guo, Zhiqiang Han, Yu‐Hui Zhang   +28 more
wiley   +1 more source

Digital morphometry of cytologic aspirate endometrial samples [Digitalna morfometrijska analiza citoloških uzoraka aspirata endometrija] [PDF]

, 2010
Unlike cervical cytology, morphological cytology criteria in the differential diagnosis of endometrium have not yet been clearly defined, and methods to allow for more precise evaluation of endometrium status have been searched for.
Babić, Damir, Barišić, Ana, Božikov, Jadranka, Ilić-Forko, Jadranka, Jurič, Danijela, Mahovlić, Vesna, Ovanin-Rakić, Ana, Rajhvajn, Sanda, Šamija Projić, Ivana, Škopljanac-Mačina, Lada, Škrablin-Kučić, Snježana   +10 more
core  

Endometriosis: A Rare Cause of Large Bowel Obstruction. [PDF]

, 2018
Large bowel obstruction can result in significant morbidity and mortality, especially in cases of acute complete obstruction. There are many possible causes, the most common in adults being colorectal cancer.
Alexandrino, G, Carvalho, R, Horta, D, Lourenço, L, Reis, J, Sobrinho, C   +5 more
core   +1 more source

High expression of S100A2 predicts poor prognosis in patients with endometrial carcinoma

BMC Cancer, 2022
Background S100A2, a member of the S100 protein family, is abnormally expressed and plays a vital role in multiple cancers. However, little is known about the clinical significance of S100A2 in endometrial carcinoma. Methods Clinicopathological data were
Qinzhen Zhang, Tianxiang Xia, Chenxiang Qi, Jun Du, Chunping Ye   +4 more
doaj   +1 more source