Results 91 to 100 of about 158,921 (215)

Delayed Diagnosis of Tuberous Sclerosis Complex Presenting as Abnormal Uterine Bleeding: A Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Tuberous sclerosis complex (TSC) is a rare multisystem genetic disorder characterized by the development of hamartomatous lesions in multiple organs. Although neurologic and dermatologic manifestations commonly lead to diagnosis during childhood, some patients remain undiagnosed until adulthood because of atypical presentations.
Kidus Tesfaye Bezabih, Hana Sisay Belay, Merid Lemma Kebede, Abebe Ketema Aderu, Mathyas Dessalegn Gebreyes, Kelil Hussein Jibicho, Adugna Assefa Talemahu, Elias Fikre Merid, Kedir Negesso Tukeni   +8 more
wiley   +1 more source

Role of Ki 67 in Normal Endometrium, Endometrial Hyperplasia and Endometrial Carcinoma: A Comparative Study [PDF]

, 2023
Introduction: Endometrial carcinoma is the 4th most common malignancy inwomen and its incidence is increasing both in developed and developing countries.
K.T Athulya Krishna Kumar, Krishnaraj Upadhyaya, Ravi Teja Cn
core  

HYPERPLASIA OF ENDOMETRIUM IN PERIMENOPAUSAL WOMEN WITH ABNORMAL UTERINE BLEEDING

Pakistan Armed Forces Medical Journal, 2020
Objective: To determine the frequency of endometrial hyperplasia in histopathology of endometrial curettings in perimenopausal women with abnormal uterine bleeding. Study Design: Prospective case series study.
Benish Khanzada, Tehmina Rehman, Saba Mansoor   +2 more
doaj   +2 more sources

Fisetin Attenuates Uterine Leiomyoma in Rats: Potential Crosstalk Between HMGB1, SphK1/S1P, and TGF‐β Signaling

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
Fisetin attenuates monosodium glutamate‐induced uterine leiomyoma by reducing sex hormones and suppressing S1P/SphK1 signaling, HMGB1‐mediated inflammation, and fibrotic markers. These coordinated effects alleviate fibrosis and restore uterine tissue architecture, highlighting fisetin as a promising natural therapeutic candidate.
Nashwa Maghraby, Esraa Khalaf, Marwa T. Hussien, Ahmed M. A. Sobh, Nagla T. Elmelegy   +4 more
wiley   +1 more source

RISK FACTORS OF TREATMENT FAILURE AND RECURRENT ENDOMETRIAL HYPERPLASIA IN WOMEN OF REPRODUCTIVE AGE WITH OBESITY

Фундаментальная и клиническая медицина, 2016
Aim: To identify the risk factors for treatment failure and recurrent endometrial hyperplasia in women of reproductive age with obesity. Materials and Methods: We performed a retrospective, case-control study. The study included 92 women
Elena A. Shakirova, Natalia V. Artymuk
doaj  

Pregnancy outcomes in infertile patients with endometrial hyperplasia with or without atypia undergoing in vitro fertilization: the early-follicular long protocol is superior to midluteal long protocol

Frontiers in Endocrinology
BackgroundAlthough in vitro fertilization (IVF) in infertile patients with endometrial hyperplasia is common after drug treatment, the pregnancy outcomes are often unsatisfactory.
Huiling An, Huiling An, Huiling An, Tongjie Li, Tongjie Li, Tongjie Li, Kai Huang, Kai Huang, Kai Huang, Hao Shi, Hao Shi, Hao Shi, Chen Wang, Chen Wang, Chen Wang, Ting Chu, Ting Chu, Ting Chu, Jun Zhai, Jun Zhai, Jun Zhai   +20 more
doaj   +1 more source

Peri‐ and Post‐Menopausal Hormone Replacement Therapy and Voice Disorder Risk: A TriNetX Study

The Laryngoscope, Volume 136, Issue 9, Page 3859-3865, September 2026.
ABSTRACT Objectives The aim of this study was to elucidate the risk of developing voice disorders among peri‐ and post‐menopausal female hormone replacement therapy (HRT) users. Methods A retrospective cohort study was conducted using the TriNetX Global Collaborative Network.
David Kayekjian, Warren B. Chun, Shaun A. Nguyen, Ashli K. O'Rourke, Kirsten D. Meenan   +4 more
wiley   +1 more source

Advances in FGF/FGFR Signaling: Implications for Disease and Therapy

MedComm, Volume 7, Issue 9, September 2026.
The FGF/FGFR signaling is indispensable for the maintenance of physiological homeostasis and governs multiple biological processes, including embryonic development, bone metabolism, angiogenesis, and neurogenesis, whereas aberrant hyperactivation of this pathway drives the progression of malignancies and autoimmune disorders, including inflammatory ...
Miaoyu Song, Xi Liu, Yang Xiao, Yongsheng Li, Huakan Zhao   +4 more
wiley   +1 more source

Prostate Cancer Development, Progression, and Therapy

MedComm – Oncology, Volume 5, Issue 3, September 2026.
This review provides an integrated overview of prostate cancer development, progression, and therapy, spanning historical milestones, molecular mechanisms, advanced research models, and emerging therapeutic strategies. It highlights recent advances in precision diagnosis, lineage plasticity, therapy resistance, and next‐generation treatments for ...
Xin Jin, Zicheng Xiao, Zexian Ding, Wei Li, Ruijiang Zeng, Yujun Shuai, Weimin Ci, Dan Xia, Xu Zhang, Haojie Huang   +9 more
wiley   +1 more source

Association of Glucagon‐Like Peptide‐1 Receptor Agonists With Cancer Risk in Older Adults With Type 2 Diabetes

Obesity, Volume 34, Issue S2, Page 75-87, September 2026.
ABSTRACT Objective The real‐world evidence on the association between glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) and cancer risk remains limited and mixed. Methods In 2013–2020 national Medicare claims data, we included cancer‐naïve patients with type 2 diabetes (T2D). We identified those who initiated GLP‐1 RA, sodium‐glucose cotransporter 2
Ying Lu, Hao Dai, Huilin Tang, William T. Donahoo, Thomas J. George, Ramon C. Sun, Sizun Jiang, Aik Choon Tan, Yi Guo, Jonathan D. Licht, John M. Allen, Kelvin P. Lee, Jingchuan Guo, Jiang Bian   +13 more
wiley   +1 more source