Results 11 to 20 of about 321,654 (178)

Fertility-Sparing Approaches in Atypical Endometrial Hyperplasia and Endometrial Cancer Patients: Current Evidence and Future Directions

International Journal of Molecular Sciences, 2022
Endometrial cancer (EC) is the fourth most common cancer in women in developed countries. Although it is usually diagnosed in postmenopausal women, its incidence has increased in young women, as well in recent decades, with an estimated rate of 4% in ...
Nayanar-Adela Contreras, J. Sabadell, P. Verdaguer, Carla Julià, M. Fernández-Montolí   +4 more
semanticscholar   +1 more source

Conservative Management of Atypical Endometrial Hyperplasia and Early Endometrial Cancer in Childbearing Age Women

Medicina, 2022
Total hysterectomy and bilateral adnexectomy is the standard treatment for atypical endometrial hyperplasia and early-stage endometrial cancer. However, the recommended surgical treatment precludes future pregnancy when these conditions are diagnosed in ...
S. Uccella, P. Zorzato, Susan Dababou, M. Bosco, M. Torella, A. Braga, M. Frigerio, B. Gardella, S. Cianci, A. Laganà, M. Franchi, S. Garzon   +11 more
semanticscholar   +1 more source

Pathology findings among women with alterations in uterine bleeding patterns in cameroon

Gynecologic Oncology Reports, 2021
Purpose: Endometrial cancer is on the rise in high-income countries but it has not been adequately studied in low-and-middle income countries especially in sub-Saharan Africa (SSA), likely due to scarce pathology facilities. The purpose of this study was
Simon M. Manga, Yuanfan Ye, Jeff M. Szychowski, Kathleen L. Nulah, Calvin Ngalla, Kaitlyn Kincaid, Teresa K.L. Boitano, Alan T. Tita, Isabel Scarinci, Warner K. Huh, Zacharie Sando, Margaret I. Liang   +11 more
doaj   +1 more source

Endometrial biopsy under direct hysteroscopic visualisation versus blind endometrial sampling for the diagnosis of endometrial hyperplasia and cancer: Systematic review and meta-analysis

Facts, views & vision in ObGyn, 2022
Background Endometrial cancer is the most common gynaecological neoplasia in western countries. Diagnosis of endometrial cancer requires an endometrial biopsy.
A. Di Spiezio Sardo, G. Saccone, J. Carugno, L. Pacheco, B. Zizolfi, S. Haimovich, T. Clark   +6 more
semanticscholar   +1 more source

Progestin Resistance and Corresponding Management of Abnormal Endometrial Hyperplasia and Endometrial Carcinoma

Cancers, 2022
Simple Summary Patients with endometrial hyperplasia (EH) and endometrial cancer (EC) often fail conservative treatment due to progestin resistance.
Mutul' Lv, Peiqin Chen, Mingzhu Bai, Yan Huang, Linxia Li, Youji Feng, H. Liao, Wenxin Zheng, Xiaojun Chen, Zhe Zhang   +9 more
semanticscholar   +1 more source

Loss of HOXA10 causes endometrial hyperplasia progressing to endometrial cancer

bioRxiv, 2022
Endometrial cancer is the fourth most common malignancy in women and the precursor lesion is endometrial hyperplasia. HOXA10 is a transcription factor that plays key roles in endometrial functions such as the endowment of receptivity, embryo implantation,
A. Mishra, Nirmalya Ganguli, S. Majumdar, Deepak Modi   +3 more
semanticscholar   +1 more source

Risk factors of endometrial cancer in patients with endometrial hyperplasia: implication for clinical treatments

BMC Women's Health, 2021
Background Endometrial hyperplasia (EH) is commonly-seen in the patients with endometrial cancer (EC), we aimed to evaluated the risk factors of EC in patients with EH, to provide evidence to the clinical prevention and treatment of EC.
Jie Zhao, Yongting Hu, Yanan Zhao, Dongmei Chen, Tingfeng Fang, M. Ding   +5 more
semanticscholar   +1 more source

Immunophenotype of Atypical Polypoid Adenomyoma of the Uterus: Diagnostic Value and Insight on Pathogenesis [PDF]

, 2020
Atypical polypoid adenomyoma (APA) is a rare uterine lesion constituted by atypical endometrioid glands, squamous morules, and myofibromatous stroma. We aimed to assess the immunophenotype of the 3 components of APA, with regard to its pathogenesis and ...
Aggarwal, Ayhan, Chiarelli, Di Palma, Fukunaga, Giampaolino, Heatley, Horita, Houghton, Jiang, Kuwashima, Lin, Longacre, Lu, Ma, Mazur, McAlpine, McCluggage, McCluggage, Moher, Nei, Nomura, Nomura, Němejcová, Ohishi, Ota, Raffone, Raffone, Raffone, Raffone, Raffone, Raffone, Ramos, Stelloo, Strickland, Takahashi, Talhouk, Terada, Travaglino, Travaglino, Travaglino, Travaglino, Travaglino, Travaglino, Travaglino, Young, Zhang   +46 more
core   +1 more source

Outcomes of women treated with progestin and metformin for atypical endometrial hyperplasia and early endometrial cancer: a systematic review and meta-analysis

International Journal of Gynecological Cancer, 2021
Objective Progestin therapy is the recommended fertility-sparing management of atypical endometrial hyperplasia or early-stage endometrial cancer in reproductive-aged women.
Jennifer J. Chae-Kim, G. Garg, L. Gavrilova-Jordan, L. Blake, Tongil Kim, Qiang Wu, C. Hayslip   +6 more
semanticscholar   +1 more source

The proliferation markers in patients with different forms of hyperplastic endometrial processes

Journal of Education, Health and Sport, 2022
Introduction: Endometrial hyperplastic processes (EHP) are characterized by recurrent course, high risk of malignancy, difficulties in diagnosing and predicting the course, which determines their great medical and social significance Objective: To ...
Yuri Krut, Nataly Zemlyana, Natalie Gaidai, Mykhailo Pavliuchenko, Iryna Amro   +4 more
doaj   +1 more source