Results 21 to 30 of about 86,474 (255)

ARID1A and PI3-kinase pathway mutations in the endometrium drive epithelial transdifferentiation and collective invasion

Nature Communications, 2019
PIK3CA mutations and ARID1A loss co-exist in endometrial neoplasms. Here, the authors show that these co-mutations drive gene expression profiles correlated with differential chromatin accessibility and ARID1A binding in the endometrial epithelium ...
Mike R. Wilson, Jake J. Reske, Jeanne Holladay, Genna E. Wilber, Mary Rhodes, Julie Koeman, Marie Adams, Ben Johnson, Ren-Wei Su, Niraj R. Joshi, Amanda L. Patterson, Hui Shen, Richard E. Leach, Jose M. Teixeira, Asgerally T. Fazleabas, Ronald L. Chandler   +15 more
doaj   +1 more source

Non-atypical endometrial hyperplasia: risk factors for occult endometrial atypia and malignancy in patients managed with hysterectomy [PDF]

Obstetrics & Gynecology Science, 2021
Objective To determine the risk factors for occult endometrial atypia and malignancy in patients diagnosed with non-atypical endometrial hyperplasia (NEH) on endometrial biopsy.
Lee Shi Hui, Selina Hui Men Chin, Charissa Goh, Lin Xiao Hui, Manisha Mathur, Timothy Lim Yong Kuei, Felicia Chin Hui Xian   +6 more
doaj   +1 more source

A new case of primary signet-ring cell carcinoma of the cervix with prominent endometrial and myometrial involvement: Immunohistochemical and molecular studies and review of the literature

World Journal of Surgical Oncology, 2012
Background As a rule, endocervical tumours with signet-ring cell are classed as metastatic extra-genital neoplasms. In a patient aged 45 years, we describe primary cervical signet-ring cell carcinoma (PCSRCC) characterized by prominent endometrial and ...
Giordano Giovanna, Pizzi Silvia, Berretta Roberto, D'Adda Tiziana   +3 more
doaj   +1 more source

Occupational exposure to pesticides and endometrial cancer in the Screenwide case-control study

Environmental Health, 2023
Background Endometrial cancer is the most common gynaecological tumour in developed countries and disease burden is expected to increase over the years. Identifying modifiable risk factors may help developing strategies to reduce the expected increasing ...
Arnau Peñalver-Piñol, Yolanda Benavente, Jon Frias-Gomez, Juan Alguacil, Miguel Santibañez, Manuel Contreras-Llanes, Paula Peremiquel-Trillas, Marta López-Querol, Sonia Paytubi, Beatriz Pelegrina, Irene Onieva, José Manuel Martínez, Sergi Fernandez-Gonzalez, Javier de Francisco, Víctor Caño, Joan Brunet, Marta Pineda, Jordi Ponce, Xavier Matias-Guiu, Francesc Xavier Bosch, Silvia de Sanjosé, Laia Alemany, Laura Costas   +22 more
doaj   +1 more source

Low grade endometrial stromal sarcoma – A series of 4 cases and review of relevant literature

Journal of Pathology of Nepal, 2015
Endometrial stromal tumors are rare uterine malignancies composed of cells resembling those of proliferative endometrial stroma. Because of their indistinct clinical and radiological features, these malignancies are very rarely diagnosed preoperatively ...
P Vijayan, LM Ilias, A Ponniah, BA Mohammed   +3 more
doaj   +1 more source

Endometrial thickness cut-off value by transvaginal ultrasonography for screening of endometrial pathology in premenopausal and postmenopausal women [PDF]

Obstetrics & Gynecology Science, 2019
ObjectiveTo assess the clinical usefulness and diagnostic accuracy of ultrasonographic measurement of endometrial thickness (ET) in women with endometrial hyperplasia or cancer (EH+).MethodsThis retrospective cohort study included 29,995 consecutive ...
Yu Ran Park, Shin Wha Lee, Yeongsin Kim, In Young Bae, Hong-Kyu Kim, Jaewon Choe, Yong-Man Kim   +6 more
doaj   +1 more source

Immunotherapy in gynecological cancers

Exploration of Targeted Anti-tumor Therapy, 2021
Immunotherapy has changed the natural history of several malignancies that, a decade ago, had a very poor prognosis, such as lung cancer and melanoma.
Domenica Lorusso, Valentina Ceni, Gennaro Daniele, Antonella Pietragalla, Vanda Salutari, Margherita Muratore, Camilla Nero, Francesca Ciccarone, Giovanni Scambia   +8 more
doaj   +1 more source

Histopathology of Endometrial Stromal Sarcoma with Emphasis on Immunohistochemistry Marker Expression: Report of Three Cases

Medical Journal of Dr. D.Y. Patil Vidyapeeth
Endometrial stromal tumors are rare uterine mesenchymal neoplasms. Endometrial stromal sarcomas (ESSs) are of endometrial stromal origin that accounts for approximately 1% of all uterine malignant neoplasms.
Narayanamoorthy Keerthyraj, Vigneswaramoorthi Vinayagamoorthi, Erli Amel Ivan, V Sriram, Govindasamy Revathi, Ramya Gandhi   +5 more
doaj   +1 more source

Endometrial Stromal Nodule: Report of a Case

Case Reports in Medicine, 2011
Endometrial stromal nodule (ESN) is the least common of the endometrial stromal tumors. They are rare neoplasms which are diagnosed in most instances by light microscopy. Although such nodules are benign, hysterectomy has been considered the treatment of
F. Z. Fdili Alaoui, H. Chaara, H. Bouguern, M. A. Melhouf, H. Fatemi, A. Belmlih, Afaf Amarti   +6 more
doaj   +1 more source

Update on Endometrial Stromal Tumours of the Uterus

Diagnostics, 2021
Endometrial stromal tumours (ESTs) are rare, intriguing uterine mesenchymal neoplasms with variegated histopathological, immunohistochemical and molecular characteristics.
Iolia Akaev, Chit Cheng Yeoh, Siavash Rahimi   +2 more
doaj   +1 more source