Results 21 to 30 of about 86,874 (288)

Molecular Insights in Endometrial Stromal Sarcomas: Exploring New Targets for Novel Therapeutic Approaches [PDF]

Biomolecules
Uterine mesenchymal tumors (UMTs) are the second most common type of tumors within the uterus corpus after endometrial carcinomas. Among the UMTs, smooth muscle neoplasms are the most common subtype, followed by endometrial stromal sarcoma (ESS).
Alice Costa, Annalisa Astolfi, Livia Gozzellino, Margherita Nannini, Gianandrea Pasquinelli, Maria Abbondanza Pantaleo   +5 more
doaj   +2 more sources

Predictive Utility of Systemic Immune Inflammation Index (SII) in Identifying Endometrial Carcinoma in Premalignant Endometrial Lesions

Van Tıp Dergisi, 2023
INTRODUCTION: It is important to detect endometrial cancer (EC) in endometrial intraepithelial neoplasia (EIN) patients. It was aimed to determine the role of systemic immune inflammation index (SII) in predicting concurrent EC in women with EIN. METHODS:
Caner Köse, Büşra Körpe, Zehra Kurdoğlu, Hilal Kokmaz, Yaprak Engin-Ustun, Vakkas Korkmaz   +5 more
doaj   +1 more source

Concerted upregulation of CLP36 and smooth muscle actin protein expression in human endometrium during decidualization [PDF]

, 2005
The human endometrium prepares for implantation of the blastocyst by reorganization of its whole cellular network. Endometrial stroma cells change their phenotype starting around the 23rd day of the menstrual cycle.
Neumaier-Wagner, Peruka, Huppertz, Berthold, Goyal, Pankaj, Rath, Werner, Miehe, Ulrich, Kadyrov, Mamed, Alfer, Joachim   +6 more
core   +1 more source

Revised guidelines for the clinical management of Lynch syndrome (HNPCC): recommendations by a group of European experts [PDF]

, 2013
Lynch syndrome (LS) is characterised by the development of colorectal cancer, endometrial cancer and various other cancers, and is caused by a mutation in one of the mismatch repair genes: MLH1, MSH2, MSH6 or PMS2.
Sampson, JR, Capella, G., Moeslein, Gabriela, Moslein, G., Vasen, Hans F. A., Sijmons RH, Renkonen-Sinisalo, L, Genuardi, M, Engel, C., Leon, M., Møller P, Gopie, JP, Bertario, Lucio, Alonso A, Heinimann, K, Genuardi, M., Tejpar, S, Burn J, Rahner, N, Engel, Christoph, PONZ DE LEON, Maurizio, Alonso, A, Wijnen, J.T., Burn, John, Lindblom, Annika, Heinimann, Karl, Lindblom, A, Tejpar, Sabine, Vasen HF, Bertario L, Leon, M.P. de, Thomas HJ, Maurizio Genuardi., Nagengast, FM, Gopie JP, Myrhoj, T., Bernstein I, Hes, Frederik J., Stormorken, Astrid, Myrhoj, Torben, Aktan-Collan, Katja, Wijnen JT, Alonso, A., Tejpar, S., Hodgson, SV, Nagengast, Fokko M., Aretz, S., Vasen, H.F., Myrhoj T, Stormorken A, Moller, P., Engel C, Järvinen HJ, Sampson, Julian R., Karagiannis, JA, Mecklin, JP, Lalloo, F., Engel, C, Capella, G, Bernstein, I., Hodgson SV, Lindblom A, Bertario, L, Jaervinen, Heikki Juhani, Gopie, Jessica P., Karagiannis, John A., Burn, J, Karagiannis JA, Frayling, I.M., Sijmons, Rolf H., Sampson JR, Rahner, N., Ponz de Leon, M, Blanco, I, Aktan Collan K, Møller, P, Hes FJ, Aktan-Collan, K, Blanco, I., Genuardi, Maurizio, Aretz, Stefan, Vasen, HF, Blanco, Ignacio, Nagengast, F.M., Thomas, Huw J. W., Stormorken, A, Lindblom, A., Gopie, J.P., Bertario, L., Moller, Pal, Thomas, H.J.W., Lalloo, Fiona, Rahner N, Renkonen-Sinisalo, Laura, Wijnen, Juul T., Alonso, Angel, Sampson, Julian Roy, Bernstein, Inge, Sijmons, RH, Capella, Gabriel, Mallorca Grp, Jarvinen, H.J., Myrhoj, T, Hes, FJ, Aretz S, Järvinen, HJ, Wijnen, JT, Mallorca group, Vasen, H.F.A., Parc Y, Karagiannis, J.A., Bernstein, I, Hodgson, Shirley V., Rahner, Nils, et al., Parc, Y., Sampson, J.R., Aretz, S, Thomas, H.J., Frayling, Ian M., Capella G, Nagengast FM, Colas, C., Renkonen-Sinisalo, L., Tejpar S, Frayling, IM, Hes, F.J., Renkonen Sinisalo L, Frayling IM, Parc, Y, Mecklin, Jukka-Pekka, Möslein G., de Leon, Maurizio Ponz, Lalloo F, Blanco I, Möslein, G, Hodgson, S.V., Lalloo, F, Heinimann, K., Mecklin, J.P., Colas, C, Thomas, HJ, Colas, Chrystelle, Frayling, Ian Martin, Parc, Yann, Heinimann K, Burn, J., Sijmons, R.H., Stormorken, A., Genuardi M, de Leon, M.P., Colas C, Mecklin JP, Aktan-Collan, K.   +153 more
core   +1 more source

Study of ER, PR and VEGF Expression in Endometrial Epithelial Neoplasms and its Association with Histological Stage and Grade of Endometrial Carcinoma [PDF]

Journal of Clinical and Diagnostic Research, 2022
Introduction: Exogenous or endogenous oestrogen induces hyperplastic endometrium which presents with abnormal uterine bleeding. Atypical endometrial hyperplasia is the precursor for endometrial carcinoma. In case of invasive carcinoma, oestrogen Receptor
SK Samim Rahaman, Rathin Hazra, Nirmalya Chakrabarti, Prasenjit Kumar Bar   +3 more
doaj   +1 more source

Lifestyle advice to reduce ovarian cancer risk [PDF]

World Cancer Research Journal, 2020
OBJECTIVE: Ovarian cancer is usually diagnosed at advanced stages; it has one of the worst prognoses among gynecologic neoplasms and it hasn’t got an effective screening program. It has modifiable risk factors in common with endometrial and breast cancer.
L. Del Pup, L. Driul, F. Peccatori
doaj   +1 more source

ARID1A and PI3-kinase pathway mutations in the endometrium drive epithelial transdifferentiation and collective invasion

Nature Communications, 2019
PIK3CA mutations and ARID1A loss co-exist in endometrial neoplasms. Here, the authors show that these co-mutations drive gene expression profiles correlated with differential chromatin accessibility and ARID1A binding in the endometrial epithelium ...
Mike R. Wilson, Jake J. Reske, Jeanne Holladay, Genna E. Wilber, Mary Rhodes, Julie Koeman, Marie Adams, Ben Johnson, Ren-Wei Su, Niraj R. Joshi, Amanda L. Patterson, Hui Shen, Richard E. Leach, Jose M. Teixeira, Asgerally T. Fazleabas, Ronald L. Chandler   +15 more
doaj   +1 more source

Non-atypical endometrial hyperplasia: risk factors for occult endometrial atypia and malignancy in patients managed with hysterectomy [PDF]

Obstetrics & Gynecology Science, 2021
Objective To determine the risk factors for occult endometrial atypia and malignancy in patients diagnosed with non-atypical endometrial hyperplasia (NEH) on endometrial biopsy.
Lee Shi Hui, Selina Hui Men Chin, Charissa Goh, Lin Xiao Hui, Manisha Mathur, Timothy Lim Yong Kuei, Felicia Chin Hui Xian   +6 more
doaj   +1 more source

A new case of primary signet-ring cell carcinoma of the cervix with prominent endometrial and myometrial involvement: Immunohistochemical and molecular studies and review of the literature

World Journal of Surgical Oncology, 2012
Background As a rule, endocervical tumours with signet-ring cell are classed as metastatic extra-genital neoplasms. In a patient aged 45 years, we describe primary cervical signet-ring cell carcinoma (PCSRCC) characterized by prominent endometrial and ...
Giordano Giovanna, Pizzi Silvia, Berretta Roberto, D'Adda Tiziana   +3 more
doaj   +1 more source

Occupational exposure to pesticides and endometrial cancer in the Screenwide case-control study

Environmental Health, 2023
Background Endometrial cancer is the most common gynaecological tumour in developed countries and disease burden is expected to increase over the years. Identifying modifiable risk factors may help developing strategies to reduce the expected increasing ...
Arnau Peñalver-Piñol, Yolanda Benavente, Jon Frias-Gomez, Juan Alguacil, Miguel Santibañez, Manuel Contreras-Llanes, Paula Peremiquel-Trillas, Marta López-Querol, Sonia Paytubi, Beatriz Pelegrina, Irene Onieva, José Manuel Martínez, Sergi Fernandez-Gonzalez, Javier de Francisco, Víctor Caño, Joan Brunet, Marta Pineda, Jordi Ponce, Xavier Matias-Guiu, Francesc Xavier Bosch, Silvia de Sanjosé, Laia Alemany, Laura Costas   +22 more
doaj   +1 more source