Results 41 to 50 of about 236,724 (287)

Immunotherapy in gynecological cancers

Exploration of Targeted Anti-tumor Therapy, 2021
Immunotherapy has changed the natural history of several malignancies that, a decade ago, had a very poor prognosis, such as lung cancer and melanoma.
Domenica Lorusso, Valentina Ceni, Gennaro Daniele, Antonella Pietragalla, Vanda Salutari, Margherita Muratore, Camilla Nero, Francesca Ciccarone, Giovanni Scambia   +8 more
doaj   +1 more source

Endometrial Stromal Nodule: Report of a Case

Case Reports in Medicine, 2011
Endometrial stromal nodule (ESN) is the least common of the endometrial stromal tumors. They are rare neoplasms which are diagnosed in most instances by light microscopy. Although such nodules are benign, hysterectomy has been considered the treatment of
F. Z. Fdili Alaoui, H. Chaara, H. Bouguern, M. A. Melhouf, H. Fatemi, A. Belmlih, Afaf Amarti   +6 more
doaj   +1 more source

Update on Endometrial Stromal Tumours of the Uterus

Diagnostics, 2021
Endometrial stromal tumours (ESTs) are rare, intriguing uterine mesenchymal neoplasms with variegated histopathological, immunohistochemical and molecular characteristics.
Iolia Akaev, Chit Cheng Yeoh, Siavash Rahimi   +2 more
doaj   +1 more source

A case of high-grade endometrial stromal sarcoma: A poignant allegory

Journal of Mid-Life Health, 2019
Endometrial stromal sarcomas (ESS) are rare tumors of endometrial stromal origin that account for approximately 1% of all uterine malignant neoplasms and are responsible for a significant proportion of mortality due to uterine malignancies.
Shashank Shekhar, Charu Sharma, Poonam Elhence, Shavina Bansal, Neha Garg   +4 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Laparoscopy and laparotomy in endometrial cancer – a meta-analysis

Archives of Medical Science, 2021
Introduction Uterine malignancies, the vast majority of which are endometrial cancers, constitute the most common type of gynecological neoplasms in developed countries.
Emilia Tupacz-Mosakowska, Anna Abacjew-Chmyłko, Dariusz Wydra   +2 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Classification of Endometrial Cancer

, 2020
Endometrial cancer is the most common malignancy of the female genital tract in the more developed regions of the world [1]. Stage of disease, i.e., the extent of tumor spread at the time of presentation, is the most significant prognostic parameter.
Åvall-Lundqvist, Elisabeth,
core   +1 more source

Synchronous Endometrial and Ovarian Adenocarcinomas in a 43-Year-Old Patient Following Infertility Treatment: A Case Report

Diagnostics
Background and Clinical Significance: This study presents a case of a 43-year-old female with a long history of infertility, treated for uterine leiomyoma and endometrial hyperplasia, over a total observation period of 42 months.
Małgorzata Gajewska, Barbara Suchońska, Joanna Blok, Wanda Gajzlerska-Majewska, Artur Ludwin   +4 more
doaj   +1 more source