Results 111 to 120 of about 48,424 (260)

MLH1 p.His112Arg Variant Is Associated With Increased Cancer Susceptibility

International Journal of Cancer, EarlyView.
ABSTRACT Lynch syndrome, a prevalent hereditary cancer predisposition, is frequently caused by pathogenic variants in the MutL homolog 1 (MLH1) mismatch repair gene. However, a significant proportion of MLH1 missense variants remain classified as variants of uncertain significance (VUS), creating clinical ambiguity.
Amal Elfatih, Issam Tout, Najwa Ahmad Doha, Tala Abu Arja, Idris Mohammed, Doua Abdelrhaman, Waseem Hasan, Chadi Saad, Hamdi Mbarek, Borbala Mifsud, Sahar Isa Da'as   +10 more
wiley   +1 more source

The mitochondrial DNA copy number and ovary‐related reproductive disorders: A bidirectional two‐sample Mendelian randomization study

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 112-120, April 2025.
Abstract Objective In the present study, a bidirectional two‐sample Mendelian randomization approach was utilized to explore potential causal relationships between mitochondrial DNA copy number (mtDNA‐CN) and ovary‐related reproductive disorders (ORRDs), including ovarian dysfunction, ovarian cyst, polycystic ovary syndrome (PCOS), premature ovarian ...
Ke Peng, Xiao Han, Congquan Wu, Qiaowen Lu, Shujun Gao   +4 more
wiley   +1 more source

The effectiveness of a training program in improving the prenatal diagnosis accuracy of placenta accreta spectrum with ultrasound

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study evaluates the effectiveness of a structured training program in improving prenatal ultrasound diagnostic accuracy for placenta accreta spectrum (PAS) and assesses trainees' ability to recognize individual ultrasound markers of PAS.
Nicha Vetvitayavatana, Pharuhas Chanprapaph, Julaporn Pooliam   +2 more
wiley   +1 more source

The effect of ovarian stimulation protocol on follicular asynchrony during in vitro fertilization – A retrospective cohort study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To examine the effect of controlled ovarian stimulation (COS) protocol on follicular synchrony in a subsequent in vitro fertilization (IVF) cycle in patients whose previous cycle was canceled due to asynchrony. Methods A single‐center retrospective‐cohort study (January 2018–March 2024), including women undergoing IVF who had: (1) a ...
Alyssa Hochberg, Maria Hincapie, Uri Amikam, Nir Kugelman, William Buckett, Shauna Reinblatt   +5 more
wiley   +1 more source

Retrospective analysis of outcome after endometrial ablation with the NovaSure device: A German single‐center experience

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Evaluation of retrospective outcomes of NovaSure treatment in patients with abnormal uterine bleeding, including safety and cost‐effectiveness, and risk factors related to therapeutic outcomes. Subgroup analysis was conducted for patients who underwent concomitant surgical procedures, required subsequent interventions, and were ...
Oliver M. Schleicher, Felix Heindl, Julia Gocke, Katharina Keller, Lothar Häberle, Alaa Hamzeh, Christian Matek, Matthias W. Beckmann, Julius Emons   +8 more
wiley   +1 more source

Patient reported outcomes and results of endometrial balloon ablation for the treatment of heavy menstrual bleeding: A single center observational cohort study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Heavy menstrual bleeding is one of the most common gynecologic disorders among women of reproductive age and has a significant impact on their physical, psychological, and social well‐being. Although international guidelines recommend medical therapy as the first‐line treatment, it may prove ineffective, poorly tolerated, or ...
Jonas Rudaitis, Patricija Marozaite, Egle Bareikiene, Vilius Rudaitis   +3 more
wiley   +1 more source

Assessment and management of dyspareunia in peri‐ and postmenopausal women: A phenotype‐based gynecologic approach

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Dyspareunia in peri‐ and postmenopausal women is common, clinically consequential, and often undertreated in gynecologic practice. Although genitourinary syndrome of menopause (GSM) is a frequent contributor, intercourse‐related pain may also reflect vestibular, pelvic floor, dermatologic, inflammatory, treatment‐related, and psychosocial ...
Marek Broul, Marcel Vančo, Jaroslava Banýrová, Aneta Hujová   +3 more
wiley   +1 more source

Endometrial pattern predicts pregnancy outcome in single-blastocyst frozen-embryo transfer: An analysis of 1383 cycles. [PDF]

Reprod Med Biol
Kuramoto K, Hamada N, Kawamura K, Egashira K, Morokuma S, Otsuka M, Yoshioka N, Kuramoto T, Kato K.   +8 more
europepmc   +1 more source

Menopause hormone therapy in women with cardiovascular risk factors or established ischemic heart disease: A joint FIGO and WHF position paper

International Journal of Gynecology &Obstetrics, EarlyView.
Integrated approach to menopausal hormone therapy in women with cardiovascular risk factors or established ischemic heart disease, from early treatment initiation and risk stratification to individualized therapy, multidisciplinary follow‐up, and health‐system recommendations.
Chiara Benedetto, Martha Gulati, Suvarna S. Khadilkar, Angela H. E. M. Maas, Federica Frezet, Gláucia Maria Moraes de Oliveira, Andrea R. Genazzani, Hema Divakar, Athena Poppas, on behalf of the World Heart Federation (WHF) and the International Federation of Gynecology and Obstetrics (FIGO)   +9 more
wiley   +1 more source

Use of natural language processing to extract uterine weight from pathology reports

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Introduction For patients requiring hysterectomy, uterine weight is an important factor affecting surgical complexity and surgical outcomes. However, uterine weight is not readily available for analysis in administrative databases. In the present study, we use natural language processing to extract uterine weight from narrative pathology text.
Steven Habbous, Alinah Surani, Ally Murji, Erik Hellsten   +3 more
wiley   +1 more source