Results 51 to 60 of about 23,379,316 (168)

Multi-omics analysis reveals shared diagnostic and therapeutic targets in endometriosis and recurrent implantation failure

Scientific Reports
Endometrial receptivity is essential for successful pregnancy, and endometriosis is widely recognized as a disruptor of this process. Poor endometrial receptivity is also a key factor contributing to recurrent implantation failure.
Jie YU, Wei WANG, Qiong LI, Lan LAN, Li-Li JIANG, Xin-Rong HE, Xiao-Wei JIANG, Yu-lin YAN, Xiao-Ming YAO, Meng-Yue WANG, Ping-Mei DUAN, Lin-Chun HUANG, Hai-Feng QI, Ting-He YU   +13 more
doaj   +1 more source

SIRT3 protects endometrial receptivity in patients with polycystic ovary syndrome

Chinese Medical Journal
. Background. The sirtuin family is well recognized for its crucial involvement in various cellular processes. Nevertheless, studies on its role in the human endometrium are limited.
Zhonghong Zeng, Hongying Shan, Mingmei Lin, Siyu Bao, Dan Mo, Feng Deng, Yang Yu, Yihua Yang, Ping Zhou, Rong Li, Yanjie Yin   +10 more
doaj   +1 more source

Interaction of sperm with endometrium can regulate genes involved in endometrial receptivity pathway in mice: An experimental study

International Journal of Reproductive BioMedicine, 2020
Background: Many researchers consider implantation and endometrial receptivity as pertinent issues in reproductive science. Although, several experiments have been performed and their results evaluated, yet there is no confirmed evidence about the ...
Marziyeh Ajdary, Zahra Zandieh, Fatemeh Sadat Amjadi, Fariborz Keyhanfar, Mehdi Mehdizadeh, Reza Aflatoonian   +5 more
doaj   +1 more source

Structural Control of Stromal‐Immune Coupling by COL24A1 Underlies Pregnancy Maintenance

Advanced Science, EarlyView.
COL24A1 emerges as a collagen‐associated regulator of maternal‐fetal interface homeostasis. Its deficiency promotes a maladaptive TIMP1‐high stromal state, impaired ECM turnover, collagen accumulation, and stromal–immune dysregulation, contributing to pregnancy loss.
Teng Wu, Lingling Xie, Wenyi Liu, Hanjie Mo, Chengshu Xie, Jing Tang, Zhaorui Wang, Peixuan Lan, Jianping Zhang, Jie Gao, Qionglan Tang, Chunwei Cao, Hui Chen   +12 more
wiley   +1 more source

P-424 Endometrial receptivity as determined by Endometrial Receptivity Analysis (ERA) can change after a successful live birth from a frozen embryo transfer (FET)

Human Reproduction, 2022
Abstract Study question Endometrial receptivity as determined by Endometrial Receptivity Analysis (ERA) can change after a successful live birth from a frozen a frozen embryo transfer (FET) Summary answer 27 of 33 patients with a ...
R Anderson, G.D Royster
openaire   +1 more source

Hyperandrogenism and Its Possible Effects on Endometrial Receptivity: A Review [PDF]

, 2023
Endometrial receptivity is a state of the endometrium defined by its readiness for embryo implantation. When the receptivity of the endometrium is impaired due to hyperandrogenism or androgen excess, this condition can lead to pregnancy loss or ...
Allia Najmie Muhammad Yusuf, Adila A. Hamid, Norhazlina Abdul Wahab, Azizah Ugusman, Mohd Helmy Mokhtar, Mohd Fariz Amri   +5 more
core   +1 more source

The Role of High Cxcl11 Expression in Ovarian Dysfunction Through NF‐κB and AKT Pathways in a Thin Endometrium Mouse Model

iNew Medicine, EarlyView.
Thin endometrium upregulates Cxcl11, which polarizes ovarian macrophages via NF‐κB/AKT, impairing ovarian function. A new uter‐ovarian signaling axis is identified. ABSTRACT Objective Thin endometrium (TE) is a recognized cause of female infertility, primarily associated with impaired uterine receptivity.
Yulu Yang, Fei Tang, Zihan Meng, Yunxi Bao, Jujun Han, Xiaohua Jiang, Jianye Wang, Ying Wang, Zhaolian Wei   +8 more
wiley   +1 more source

Varied cellular abnormalities in thin vs. normal endometrium in recurrent implantation failure by single-cell transcriptomics

Reproductive Biology and Endocrinology
Background Reduced endometrium thickness and receptivity are two important reasons for recurrent implantation failure (RIF). In order to elucidate differences between these two types of endometrial defects in terms of molecular signatures, cellular ...
Xiaoying Fu, Xiaoyan Guo, Han Xu, Yini Li, Bihui Jin, Xirong Zhang, Chongyi Shu, Yuhang Fan, Yiqi Yu, Yuqing Tian, Jiao Tian, Jing Shu   +11 more
doaj   +1 more source

Exploring vaginal microbiota–tissue resident stem cell crosstalk: VCAM1/Akt signaling ‐mediated enhancement of regenerative capacity

Interdisciplinary Medicine, EarlyView.
Vaginal microbiota‐derived secretory factors enhance the regenerative capacity of human endometrial stem cells by upregulating VCAM1 and activating PI3K/Akt signaling. This microbiota–stem cell crosstalk promotes self‐renewal, migration, multilineage differentiation, and metabolic reprogramming in vitro and in vivo, establishing a novel microbiota ...
Soo‐Rim Kim, Eun‐Kyung Min, Choon‐Mi Lee, Kun‐Hee Na, Chan Hum Park, YunJae Jung, Hwa‐Yong Lee   +6 more
wiley   +1 more source

Comparative analysis of endometrial gland imaging and pinopode detection for assessing endometrial receptivity

Reproductive Biology and Endocrinology
This study aimed to obtain high-resolution endometrial gland images under high-definition hysteroscopy from in vitro fertilization and embryo transfer (IVF-ET) patients and perform image recognition to analyze their density and opening size. Concurrently, the number and morphology of pinopodes in the endometrial samples were observed using scanning ...
Min-bo Zhu, Bei-lei Chen, Meng Cen, Li-ping Chen, Zheng Shi   +4 more
openaire   +3 more sources