Results 111 to 120 of about 31,891 (279)

The Ultrasonography Characteristics of Borderline Ovarian Tumor Subtypes

open access: yes
Journal of Ultrasound in Medicine, EarlyView.
Roni Yoeli‐Bik   +6 more
wiley   +1 more source

Dual Role of Natural Killer Cells in Early Pregnancy: Immunopathological Implications and Therapeutic Potential in Recurrent Spontaneous Abortion and Recurrent Implantation Failure

open access: yesCell Proliferation, EarlyView.
This article elaborates on the role of NK cells in early pregnancy from multiple perspectives, including molecular mechanisms and therapeutic interventions. It also discusses how NK cell dysfunction contributes to RSA and RIF, aiming to provide insights for future research on NK cell mechanisms and clinical treatment of RSA and RIF.
Defeng Guan   +5 more
wiley   +1 more source

Dynamic phenotypes of preclinical and clinical obesity in relation to new‐onset cancer risk: A longitudinal analysis from the UK biobank

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aim The definition of clinical obesity was newly announced. Our study aims to investigate the relationship between different states of obesity and dysfunctions due to obesity with cancer incidence and mortality. Methods The prospective cohort study from the UK Biobank included 220 016 participants.
Manrong Xu   +5 more
wiley   +1 more source

Molecular manipulation of keratin 8/18 intermediate filaments: modulators of FAS-mediated death signaling in human ovarian granulosa tumor cells [PDF]

open access: yes, 2016
Background: Granulosa cell tumors (GCT) are a rare ovarian neoplasm but prognosis is poor following recurrence. Keratin intermediate filaments expressed in these tumors are a diagnostic marker, yet paradoxically, may also constitute a target for ...
Davis, John S.   +4 more
core   +3 more sources

Emerging roles for integrated stress response signaling in homeostasis

open access: yesThe FEBS Journal, EarlyView.
Integrated stress response (ISR), an evolutionarily conserved eukaryotic stress‐adaptive program in eukaryotes, has also been implicated in homeostatic functions. This review covers a broad body of literature and presents several homeostatic functions of ISR in the absence of stress: (a) developmental processes (morphogenesis, differentiation, aging), (
Shyama Nandakumar   +2 more
wiley   +1 more source

PI3Kγ in Tumour Inflammation: Bridging Immune Response and Cancer Progression—A Mini‐Review

open access: yesImmunology, EarlyView.
Myeloid cell PI3Kγ can be activated by G Protein‐Coupled Receptors or Receptor Tyrosine Kinases. Once activated, PI3Kγ promotes integrin activation as well as Akt and mTOR activation, thereby promoting transcription of immune‐suppressive and pro‐angiogenic factors, such as Arginase, IL‐10, TGFβ and VEGF‐A.
Anghesom Ghebremedhin, Judith A. Varner
wiley   +1 more source

Case Report: Two instances of lung metastasis in low-grade endometrial stromal sarcoma

open access: yesFrontiers in Oncology
BackgroundLow-grade endometrial stromal sarcoma (LGESS) with pulmonary metastasis is a rare malignant mesenchymal tumor. LGESS is composed of cells resembling proliferative endometrial stromal cells.
Anying Long   +4 more
doaj   +1 more source

Unus pro omnibus, omnes pro uno: A novel, evidence-based, unifying theory for the pathogenesis of endometriosis [PDF]

open access: yes, 2017
The theory of retrograde menstruation as aetiopathogenesis of endometriosis formulated by John Sampson in 1927 shows clear shortcomings: this does not explain why retrograde menstruation is a physiological process that affects 90% of women, while ...
Acien   +203 more
core   +1 more source

Morphological features of serosa‐associated lymphoid clusters of the rat parietal pleura: Exploring a relatively unexplored system

open access: yesJournal of Anatomy, EarlyView.
This study explored serosa‐associated lymphoid clusters in rat pleura (pSALCs), identifying their distribution and categorizing them into four morphological types. Data provided by this study form the basis for future morphological comparisons with humans and the potential to extrapolate functional characteristics of pSALCs from experimental studies in
Rosa E. Lagerwerf   +4 more
wiley   +1 more source

Ossifying luteinized thecoma of the ovary with endometrial adenocarcinoma

open access: yesIndian Journal of Pathology and Microbiology, 2009
Luteinized thecomas are one of the sex cord stromal tumors of the ovary rarely undergoing ossification. We report a case of a 66-year-old post-menopausal female with the chief complaint of uterine bleeding of 7 months duration.
Pervatikar S, Rao R, Dinesh U
doaj  

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