A Rare Variant of Ovarian Fibroma With Minor Sex Cord Elements: A Unique Expression of Stromal Differentiation. [PDF]
Rathore S, Babar K, Javaid N, Saleh A.
europepmc +1 more source
Neutrophil‐based immunotherapy: A metabolic lens on mechanisms and therapeutic implications
TAN metabolic reprogramming critically contributes to tumour immune evasion. A 4‑Tier TAN‑MetaC classification framework is proposed, along with an overview of translational opportunities and bottlenecks for TAN metabolism‑targeted immunotherapies. Abstract Background Tumor‐associated neutrophils (TANs) serve as pivotal immune modulators in the tumor ...
Wenchao Xu +4 more
wiley +1 more source
Diagnostic Accuracy of Preoperative Magnetic Resonance Imaging for Detecting Cervical Stromal Invasion in Endometrial Cancer: A Prospective Observational Study. [PDF]
Rami Reddy S R +3 more
europepmc +1 more source
Generation and Characterization of a Rdh1‐iCre Line to Study Uterine Glandular Biology
ABSTRACT The uterus is an essential organ for fetal development in most mammals. Uterine glands, highly conserved structures in the mammalian uterus, play critical roles in the establishment and maintenance of pregnancy and have been implicated in the pathogenesis of uterine diseases, including endometrial cancer and endometriosis.
Mana Ohtomo +11 more
wiley +1 more source
Case series analysis of immunophenotypic evolution during recurrence of low-grade endometrial stromal sarcoma: implications for molecular stability and clinical management. [PDF]
Li J, Zhang L, Chen T.
europepmc +1 more source
A key component of the collagen internalization and lysosomal degradation cellular machinery, uPARAP may contribute to cancer progression. Here, the authors explored the expression of uPARAP in gastrointestinal stromal tumors using well‐annotated clinical patient samples and specimens from cell line‐ and patient‐derived xenografts.
Chao‐Chi Wang +10 more
wiley +1 more source
The interaction between inflammation and estrogen in adenomyosis : from molecular mechanisms to therapeutic strategies. [PDF]
Li F +6 more
europepmc +1 more source
Abstract Evaluation of the pharmacokinetics (PK) of new drugs in Japanese individuals is regularly requested by the Japanese regulatory agency prior to participation in global clinical trials or for bridging approaches for regulatory approval. However, the need for PK assessments in the Japanese population may be less compelling for monoclonal ...
Paridhi Gupta +2 more
wiley +1 more source
Metastatic High-Grade Endometrial Stromal Sarcoma Presenting With Recurrent Bilateral Pneumothoraces. [PDF]
Chakalian H +4 more
europepmc +1 more source
EOPC is a distinct clinicopathological entity separable from SOPC, differing fundamentally in genetic susceptibility, TMPRSS2:ERG fusion frequency, and survival outcomes. Although research remains nascent, this review provides the first comprehensive synthesis of current evidence, offering a critical foundation to guide future investigations into this ...
Xingyu Xiong +8 more
wiley +1 more source

