Results 111 to 120 of about 35,727 (243)
European Journal of Haematology, EarlyView.SAMHD1 regulates intracellular dNTP pools, influencing lentiviral transduction, gene therapy efficiency, and disease progression in pediatric hematological malignancies. Integrated bioinformatics and targeted strategies, including CRISPR and pharmacological inhibition, highlight its therapeutic potential.
Waseem Alzamzami
wiley +1 more source
Sex cord-like elements in Müllerian lesions: Report of two rare cases and review of the literature
Human Pathology ReportsSex cord-like elements (SCLEs) are uncommon in non-ovarian sex cord lesions in the female genital tract and are most commonly observed in uterine endometrial stromal tumors (EST) and uterine tumors resembling ovarian sex cord tumors (UTROSCT).
Bahadir Yildiz +5 more
doaj +1 more source
Uterine sarcomas: clinical presentation and MRI features
Diagnostic and Interventional Radiology, 2015 Uterine sarcomas are a rare heterogeneous group of tumors of mesenchymal origin, accounting for approximately 8% of uterine malignancies. They comprise leiomyosarcoma, endometrial stromal sarcoma, undifferentiated endometrial sarcoma, and adenosarcoma ...
Pedro Santos, Teresa Margarida Cunha
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Ovarian stromal tumor with minor sex cord elements with coexistent endometrial carcinoma
Indian Journal of Medical and Paediatric Oncology, 2013 Ovarian stromal tumor with minor sex cord elements is a rare tumor. It is composed of predominantly fibrothecomatous tumor with scattered minor sex cord elements in less than 10% of the tumor area.
Sunesh Kumar +3 more
doaj +1 more source
A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer
The FEBS Journal, EarlyView.Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou +4 more
wiley +1 more source
Diagnostic Pathology, 2019 Background Metastatic tumors to the pancreas are uncommon, accounting for approximately 2% of pancreatic malignancies. The most common primary tumors to give rise to pancreatic metastases are carcinomas. Case presentation A 50-year old female patient was
Aoife J. McCarthy +5 more
doaj +1 more source
Beyond the chaos: How architecture structures tumour biology
The FEBS Journal, EarlyView.Tissue architecture shapes tumour initiation and progression through multiple interconnected layers continuously remodelled over time. This review outlines how physical forces, biochemical cues, cellular niches and systemic influences contribute to tumour evolution.
Lea Dörner +3 more
wiley +1 more source
Ossifying luteinized thecoma of the ovary with endometrial adenocarcinoma
Indian Journal of Pathology and Microbiology, 2009 Luteinized thecomas are one of the sex cord stromal tumors of the ovary rarely undergoing ossification. We report a case of a 66-year-old post-menopausal female with the chief complaint of uterine bleeding of 7 months duration.
Pervatikar S, Rao R, Dinesh U
doaj
PPAR-alpha: a novel target in pancreatic cancer [PDF]
, 2015 Background: Current targeted therapies in pancreatic cancer have been ineffective. The tumor stroma, including intra- and peri-tumoral inflammation and fibrosis, is increasingly implicated in pancreatic cancer.
Hua, Alexander Mach
core +1 more source
Journal of Periodontal Research, EarlyView.The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag +6 more
wiley +1 more source