Sex cord-like elements in Müllerian lesions: Report of two rare cases and review of the literature
Sex cord-like elements (SCLEs) are uncommon in non-ovarian sex cord lesions in the female genital tract and are most commonly observed in uterine endometrial stromal tumors (EST) and uterine tumors resembling ovarian sex cord tumors (UTROSCT).
Bahadir Yildiz +5 more
doaj +1 more source
Metabolism within the tumor microenvironment and its implication on cancer progression: an ongoing therapeutic target [PDF]
Since reprogramming energy metabolism is considered a new hallmark of cancer, tumor metabolism is again in the spotlight of cancer research. Many studies have been carried out and many possible therapies have been developed in the last years.
Abdel-Aziz +431 more
core +2 more sources
Mapping Collective Forces of Lung Cancer Spheroids Using Traction Force Microscopy
The application of conventional TFM to cancer spheroids revealed not only a size‐dependent traction force when spheroids were in non‐wetting transition state, but also a positive correlation of this force with the spheroid dispersion capacity. Moreover, the onset of spheroid dispersion was accompanied by a pronounced suppression of spheroid traction ...
Qing Zhang +3 more
wiley +1 more source
Persistent low-grade endometrial stromal tumor during two consecutive pregnancies-a case report and review of literature [PDF]
Man Wa Lui +4 more
openalex +1 more source
ABSTRACT Nonpuerperal uterine inversion (NPUI) due to endometrial carcinosarcoma can present in an acute manner with life‐threatening complications. The rare presentation of uterine inversion outside of the puerperium caused by a malignant etiology, which was further complicated by the urgent need for intervention, makes this case crucial in ...
Aman Kaur More +3 more
wiley +1 more source
Ossifying luteinized thecoma of the ovary with endometrial adenocarcinoma
Luteinized thecomas are one of the sex cord stromal tumors of the ovary rarely undergoing ossification. We report a case of a 66-year-old post-menopausal female with the chief complaint of uterine bleeding of 7 months duration.
Pervatikar S, Rao R, Dinesh U
doaj
Long-term results of a multicenter SAKK trial on high-dose ifosfamide and doxorubicin in advanced or metastatic gynecologic sarcomas [PDF]
Background: Dose intensive chemotherapy has not been tested prospectively for the treatment of gynecologic sarcomas. We investigated the antitumor activity and toxicity of high-dose ifosfamide and doxorubicin, in the context of a multidisciplinary ...
Cerny, T. +8 more
core
Minimal residual disease in solid tumors: Clinical applications and future directions
Abstract Minimal residual disease (MRD) refers to the presence of residual cancer cells or tumor‐derived fragments that persist after treatment and remain undetectable by conventional imaging or protein‐based assays. Circulating tumor DNA (ctDNA) has emerged as a dynamic biomarker for MRD detection.
Theresa Abdo +8 more
wiley +1 more source
Beyond bacterial defences: the role of lysozyme in cancer
Lysozyme (LYZ) is a multi‐functional secreted factor that encompasses both antibacterial and immunomodulatory functions. Emerging evidence highlights its complex role in tumour progression by directly influencing tumour cells and modulating the immune microenvironment.
Lei Wang +4 more
wiley +1 more source
Flow cytometric assessment of DNA‐ploidy and S‐phase fraction in malignant tumors is compromised by the heterogeneity of cell subpopulations derived from the malignant and surrounding connective tissue, e.g., tumor, stromal and inflammatory cells.
Rainer Kimmig +3 more
doaj +1 more source

