Results 61 to 70 of about 111,900 (264)

Immunosuppressive Extracellular Vesicles as a Linking Factor in the Development of Tumor and Endometriotic Lesions in the Gynecologic Tract

Cells, 2022
Both gynecological tumors and endometriosis require for their development a favorable environment, termed in the case of tumors a “pre-metastatic niche” and in case of endometriosis a “pro-endometriotic niche”.
Karolina Soroczynska, Lukasz Zareba, Magdalena Dlugolecka, Malgorzata Czystowska-Kuzmicz   +3 more
doaj   +1 more source

Lenvatinib Plus Paclitaxel as Second‐Line Therapy for Advanced Gastric Cancer Patients: A Dose Escalation Exploratory Study

Advanced Science, EarlyView.
This study determines the maximum tolerated dose of lenvatinib in combination with paclitaxel as second‐line therapy for advanced gastric cancer patients. A dynamic network biomarker panel associated with patient prognosis and response to treatment is established.
Chenfei Zhou, Jinling Jiang, Liting Guo, Wenqi Xi, Junwei Wu, Qu Cai, Jun Ji, Feng Qi, Jun Zhang   +8 more
wiley   +1 more source

Advances on Albumin‐Based Carriers for Anticancer Drug Delivery

Advanced NanoBiomed Research, EarlyView.
This study systematically classifies the drug delivery modes of albumin by examining the characteristics of its surface‐active groups and internal binding sites. It provides an in‐depth analysis of various drug delivery strategies and their corresponding targeting mechanisms.
Ruoli Zhou, Rongbin Zhong, Zhonghui Luo, Hua Wei, Cui‐Yun Yu   +4 more
wiley   +1 more source

Engineering antibodies with cancer‐associated binding sites

BMEMat, EarlyView.
This review describes antibodies that perform direct/indirect roles in cancer treatment by binding to effective targets and discusses how antibodies kill tumors and modulate tumor microenvironment through these targets. The classification of expression systems for antibody production is summarized to guide appropriate selection based on different ...
Yinqi Tian, Yumeng Pan, Yingchun Zhang, Fangling Wang, Zejun Wang   +4 more
wiley   +1 more source

Endometrial stromal sarcoma: Retrospective analysis of a tertiary care experience from India

Cancer Research, Statistics, and Treatment, 2020
Background: Endometrial stromal tumors are rare tumors of mesenchymal origin, conventionally classified as low-grade and high-grade tumors based on the mitotic count.
Rajit Rattan, Pragyat Thakur, Ankita Gupta, Raviteja Miriyala, Nagarjun Ballari, Bhavana Rai   +5 more
doaj   +1 more source

Identification of Anoikis‐Related Subgroups and Prognosis Model in Colon Cancer

Cancer Nexus, EarlyView.
ABSTRACT Background Anoikis represents a distinct type of programmed cell death that serves a critical function in tumor development and metastatic. Despite its significance, there remains a notable gap in comprehensive studies that explore the role of Anoikis specifically within the context of colon cancer (CC). Thus, it becomes imperative to pinpoint
Shaokang Yang, Peng Yang, Zhicheng Liu, Yujia Chen, Qitong He, Daguang Wang   +5 more
wiley   +1 more source

Morbidity of radical surgery and postoperative radiotherapy in cervical cancer

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Cervical cancer is among the most common cancers affecting women worldwide. The standard treatment for early‐stage cervical cancer (International Federation of Gynecology and Obstetrics [FIGO] 2018 stages IA1–IB2, IIA1) typically involves a radical or simple hysterectomy with lymph node assessment.
Nathalia Mora‐Soto, Carolina Morante‐Caicedo, Maria Caicedo‐Martínez, David Viveros‐Carreño, Emmanuel Sánchez Díaz, Juliana Rodríguez, Santiago Vieira, Jonathan A. Peralta, Nadeem R. Abu‐Rustum, Rene Pareja   +9 more
wiley   +1 more source

Elevated plasma levels of the pituitary hormone Cthrc1 in individuals with red hair but not in patients with solid tumors. [PDF]

PLoS ONE, 2014
An increasing number of studies report that Cthrc1 is expressed in various cancer cells. The present study sought to identify which cells in tumors and remodeling tissues express Cthrc1 and investigate the range of circulating human Cthrc1 levels in ...
Christine W Duarte, J Patrizia Stohn, Qiaozeng Wang, Ivette F Emery, Andrew Prueser, Volkhard Lindner   +5 more
doaj   +1 more source

Endometrial stromal sarcomas with BCOR‐rearrangement harbor MDM2 amplifications

The Journal of Pathology: Clinical Research, 2020
Recently a novel subtype of endometrial stromal sarcoma (ESS) defined by recurrent genomic alterations involving BCOR has been described (HGESS‐BCOR). We identified a case of HGESS‐BCOR with a ZC3H7B‐BCOR gene fusion, which harbored an amplification of ...
F. Kommoss, K. Chang, D. Stichel, A. Banito, David T. W. Jones, C. Heilig, S. Fröhling, F. Sahm, A. Stenzinger, W. Hartmann, G. Mechtersheimer, H. Sinn, D. Schmidt, F. Kommoss, A. von Deimling, C. Koelsche   +15 more
semanticscholar   +1 more source

New histopathological and molecular findings in gynecological cancers

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract This review covers significant developments in the pathological classification of gynecological tumors in recent years. Topics covered include The Cancer Genome Atlas (TCGA) Classification of endometrial carcinomas and how to incorporate this into routine reporting, the fact that most synchronous endometrial and ovarian endometrioid carcinomas
W. Glenn McCluggage
wiley   +1 more source