Results 71 to 80 of about 35,905 (266)

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

A case of ovarian endometrial stromal sarcoma: Radiological and histopathological findings

Radiology Case Reports, 2023
Endometrial stromal sarcoma (ESS) is an uncommon uterine mesenchymal neoplasm. The primary extra-uterine location of ESS is a very rare occurrence.We present a case of a 39-year-old woman presented with severe abdominal pain, MRI showed bilateral ovarian
Meryem Sqalli Houssaini, MD, Meriem Haloua, PhD, Abdelaali Yahya Mourabiti, MD, Layla Tahiri, PhD, Fatima Zohra Fdili Alaoui, PhD, Amal Akammar, PhD, Nizar El Bouardi, PhD, Badreedine Alami, PhD, Moulay Youssef Alaoui Lamrani, PhD, Mustapha Maaroufi, PhD, Meryem Boubbou, PhD   +10 more
doaj   +1 more source

Androgen receptor expression in human ovarian and uterine tissue of long term androgen-treated transsexual women [PDF]

, 1994
Androgen receptor (AR) modulation in human uteri and ovaries of long term androgen-treated transsexual female patients was investigated. Androgen receptor expression was evaluated immunohistochemically in the ovaries of 11 and the endometria and ...
Brinkmann, A.O. (Albert), Chadha, D., Huikeshoven, F.J. (Frans), Kwast, Th.H. (Theo) van der, Pache, T.D.   +4 more
core   +2 more sources

IFITM1, CD10, SMA, and h-caldesmon as a helpful combination in differential diagnosis between endometrial stromal tumor and cellular leiomyoma [PDF]

, 2021
Weilin Zhao, Mei Cui, Ruiqi Zhang, Xihua Shen, Xin Xiong, Xinhua Ji, Tao Lin, Wei Jia, Lijuan Pang, Zhenzhu Sun, Wang Chun, Hong Zou   +11 more
openalex   +1 more source

Molecular Insights in Endometrial Stromal Sarcomas: Exploring New Targets for Novel Therapeutic Approaches

Biomolecules
Uterine mesenchymal tumors (UMTs) are the second most common type of tumors within the uterus corpus after endometrial carcinomas. Among the UMTs, smooth muscle neoplasms are the most common subtype, followed by endometrial stromal sarcoma (ESS).
Alice Costa, Annalisa Astolfi, Livia Gozzellino, Margherita Nannini, Gianandrea Pasquinelli, Maria Abbondanza Pantaleo   +5 more
doaj   +1 more source

Stromal Liver Kinase B1 [STK11] Signaling Loss Induces Oviductal Adenomas and Endometrial Cancer by Activating Mammalian Target of Rapamycin Complex 1 [PDF]

, 2012
Germline mutations of the Liver Kinase b1 (LKB1/STK11) tumor suppressor gene have been linked to Peutz-Jeghers Syndrome (PJS), an autosomal-dominant, cancer-prone disorder in which patients develop neoplasms in several organs, including the oviduct ...
Crum, Christopher Paul, Kaneko-Tarui, Tomoko, Tanaka, Yoshihiro, Tanwar, Pradeep, Teixeira, Jose M., Zhang, LiHua   +5 more
core   +3 more sources

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

BMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan, Qiujie Fang, Cao Fei, Ziyuan Wang, Zhaowei Chen, Guojun Chen, Zhiming Xu, Shu Xu, Zhitong Chen   +8 more
wiley   +1 more source

Biomaterial design strategies for enhancing mitochondrial transplantation therapy

BMEMat, EarlyView.
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang, Yushan Zhang, Hang Li, Sirui Peng, Donghao Lyu, Chunxiao Zhou, Sheng Ding, Zujian Feng, Pingsheng Huang, Chuangnian Zhang, Hongjun Wang, Deling Kong, Weiwei Wang   +12 more
wiley   +1 more source

Sclerosing perivascular epithelioid cell tumor of the uterus: A rare entity posing diagnostic challenge

Journal of Mid-Life Health, 2022
Perivascular epithelioid cell tumor (PEComa) is a rare mesenchymal uterine tumor and the histological variant, sclerosing PEComa is exceedingly rare. Sclerosing PEComas preferentially occur in the retroperitoneum and occurrence in the uterine corpus is ...
Reetu Kundu, Pradip Kumar Saha, Pranab Dey   +2 more
doaj   +1 more source

Detection of recurrent endometrial cancer via DNA methylation analysis of cervicovaginal self‐samples and urine

International Journal of Cancer, EarlyView.
What's New? Post‐treatment surveillance for endometrial cancer aims to detect recurrence early, potentially improving outcome. Emerging evidence suggests that DNA methylation analysis of self‐collected cervicovaginal and urine samples is a promising approach.
Annick J. Nouwens, Mirte Schaafsma, Nienke E. van Trommel, Jenneke C. Kasius, Renske D. M. Steenbergen, Maaike C. G. Bleeker   +5 more
wiley   +1 more source