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Endometriosis is a common inflammatory disease characterized by the presence of tissue outside the uterus that resembles endometrium, mainly on pelvic organs and tissues. It affects ~5-10% of women in their reproductive years - translating to 176 million women worldwide - and is associated with pelvic pain and infertility.
K. Zondervan+5 more
semanticscholar +8 more sources
Pelvic endometriosis is a complex syndrome characterized by an estrogen-dependent chronic inflammatory process that affects primarily pelvic tissues, including the ovaries.
S. Bulun+9 more
semanticscholar +3 more sources
ESHRE guideline: endometriosis
STUDY QUESTION How should endometriosis be diagnosed and managed based on the best available evidence from published literature? SUMMARY ANSWER The current guideline provides 109 recommendations on diagnosis, treatments for pain and infertility ...
C. Becker+14 more
semanticscholar +1 more source
The Main Theories on the Pathogenesis of Endometriosis
Endometriosis is a complex disease, which is defined by abnormal growth of endometrial tissue outside the uterus. It affects about 10% of women of reproductive age all over the world. Endometriosis causes symptoms that notably worsen patient’s well-being—
Jelizaveta Lamceva+2 more
semanticscholar +1 more source
Diagnosis and management of endometriosis
Endometriosis ...
C. Allaire, M. Bedaiwy, P. Yong
semanticscholar +1 more source
Pathophysiology, diagnosis, and management of endometriosis
Endometriosis affects approximately 190 million women and people assigned female at birth worldwide. It is a chronic, inflammatory, gynecologic disease marked by the presence of endometrial-like tissue outside the uterus, which in many patients is ...
A. Horne, S. Missmer
semanticscholar +1 more source
Peritoneal immune microenvironment of endometriosis: Role and therapeutic perspectives
Endometriosis, an estrogen-dependent chronic inflammatory disease characterized by the growth of endometrium-like tissues outside the uterine cavity, affects 10% of reproductive-age women.
Siman Chen+5 more
semanticscholar +1 more source
Key Points Question What biological mechanisms are associated with endometriosis with mental health comorbidities? Findings This genetic association study of 8276 women with endometriosis and 194 000 female controls found that pleiotropy is likely ...
D. Koller+8 more
semanticscholar +1 more source
Endometriosis is a “mysterious” disease and its exact cause has not yet been established. Among the etiological factors, congenital, environmental, epigenetic, autoimmune and allergic factors are listed.
B. Smolarz, K. Szyłło, H. Romanowicz
semanticscholar +1 more source
Endometriosis-associated infertility: From pathophysiology to tailored treatment
Despite the clinically recognized association between endometriosis and infertility, the mechanisms implicated in endometriosis-associated infertility are not fully understood.
Giulia Bonavina, H. Taylor
semanticscholar +1 more source