Mapping the temporal and spatial dynamics of the human endometrium in vivo and in vitro
Nature Genetics, 2021 The endometrium, the mucosal lining of the uterus, undergoes dynamic changes throughout the menstrual cycle in response to ovarian hormones. We have generated dense single-cell and spatial reference maps of the human uterus and three-dimensional ...
Luz Garcia-Alonso +2 more
exaly +2 more sources
Cyclic Decidualization of the Human Endometrium in Reproductive Health and Failure [PDF]
Endocrine Reviews, 2014 Jan J Brosens
exaly +3 more sources
Physiology of the Endometrium and Regulation of Menstruation
Physiological Reviews, 2020 The physiological functions of the uterine endometrium (uterine lining) are preparation for implantation, maintenance of pregnancy if implantation occurs, and menstruation in the absence of pregnancy.
Hilary O D Critchley +1 more
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Estrogen Receptor Function: Impact on the Human Endometrium
Frontiers in Endocrinology, 2022 The physiological role of estrogen in the female endometrium is well established. On the basis of responses to steroid hormones (progesterone, androgen, and estrogen), the endometrium is considered to have proliferative and secretory phases. Estrogen can
Kun Yu +5 more
doaj +2 more sources
Progesterone and Estrogen Signaling in the Endometrium: What Goes Wrong in Endometriosis?
International Journal of Molecular Sciences, 2019 In the healthy endometrium, progesterone and estrogen signaling coordinate in a tightly regulated, dynamic interplay to drive a normal menstrual cycle and promote an embryo-receptive state to allow implantation during the window of receptivity.
Ryan M Marquardt +2 more
exaly +2 more sources
Decidualization of the human endometrium
Reproductive Medicine and Biology, 2018 Decidualization of the human endometrium, which involves a dramatic morphological and functional differentiation of human endometrial stromal cells (ESCs), is essential for the establishment of a successful pregnancy.
Hidetaka Okada, Hiromi Murata
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Loss of HDAC3 results in nonreceptive endometrium and female infertility
Science Translational Medicine, 2019 Histone deacetylase 3 plays a critical role for early pregnancy through transcriptional regulation of COL1A1 and COL1A2 genes. Connecting the dots in endometriosis Endometriosis is a clinical condition in which deposits of endometrium (uterine lining ...
Tae Hoon Kim +2 more
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Endometrium and endometriosis tissue mitochondrial energy metabolism in a nonhuman primate model
Reproductive Biology and Endocrinology, 2019 Background Endometriosis is the growth of uterine lining (endometrium) outside of the uterus. In other chronic inflammatory diseases, mitochondrial dysfunction is suspected of playing a role in disease pathogenesis.
Hannah M. Atkins +5 more
doaj +2 more sources
How uterine microbiota might be responsible for a receptive, fertile endometrium
Human Reproduction Update, 2018 Marilen Benner +2 more
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Comparison of diclofenac suppository administration time on post-operative pain in transvaginal oocyte retrieval under general anesthesia: a double-blind randomized clinical trial [PDF]
Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān, 2021 Introduction: Considering the sensitive morale of patients undergoing in vitro fertilization, there is controversy regarding the severity of pain experienced after oocyte retrieval, the appropriate analgesic drug and the time of its administration in ...
Pouran Hajian +3 more
doaj +1 more source