Results 81 to 90 of about 200,055 (385)

Apoptosis is increased and cell proliferation is decreased in out-of-phase endometria from infertile and recurrent abortion patients

Reproductive Biology and Endocrinology, 2010
Background Various endometrial abnormalities have been associated with luteal phase deficiency: a significant dyssynchrony in the maturation of the glandular epithelium and the stroma and a prevalence of out-of-phase endometrial biopsy specimens.
Irigoyen Marcela, Alfie Margarita, Vighi Susana, Olivares Carla, Meresman Gabriela F, Etchepareborda Juan J   +5 more
doaj   +1 more source

A polymorphism in a let-7 microRNA binding site of KRAS in women with endometriosis. [PDF]

, 2012
Endometriosis is found in 5-15% of women of reproductive age and is more frequent in relatives of women with the disease. Activation of KRAS results in de novo endometriosis in mice, however, activating KRAS mutations have not been identified in women ...
Chan, Elcie, Flores, Idhaliz, Grechukhina, Olga, Massasa, Efi, Paranjape, Trupti, Petracco, Rafaella, Popkhadze, Shota, Taylor, Hugh S, Weidhaas, Joanne B   +8 more
core   +1 more source

Inhibition of Glutamine Metabolism Attenuates Tumor Progression Through Remodeling of the Macrophage Immune Microenvironment

Advanced Biology, EarlyView.
The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li, Sepehr Akhtarkhavari, Sumeng Qi, Jiawei Fan, Tu‐Yung Chang, Yao‐An Shen, JinMing Yang, Barbara S. Slusher, Ie‐Ming Shih, Stephanie Gaillard, Tian‐Li Wang   +10 more
wiley   +1 more source

The Role of Combined Treatment of Granulocyte Colony-stimulating Factor and Oestrogen in Treatment of Thin Endometrium: A Rat Model

Journal of Human Reproductive Sciences
Background: Thin endometrium, described as endometrial thickness below 7 mm on embryo transfer day in assisted reproduction cycles, is associated with decreased pregnancy rates.
Inci Kahyaoglu, Gülnur Take Kaplanoglu, Gökçe Nur Arik Erol, Serkan Kahyaoglu   +3 more
doaj   +1 more source

Differential Expression Pattern of Goat Uterine Fluids Extracellular Vesicles miRNAs during Peri-Implantation

Cells, 2021
Early pregnancy failure occurs when a mature embryo attaches to an unreceptive endometrium. During the formation of a receptive endometrium, extracellular vesicles (EVs) of the uterine fluids (UFs) deliver regulatory molecules such as small RNAs to ...
Yanshe Xie, Guangbin Liu, Xupeng Zang, Qun Hu, Chen Zhou, Yaokun Li, Dewu Liu, Linjun Hong   +7 more
doaj   +1 more source

Non-Coding RNA Sequencing of Equine Endometrium During Maternal Recognition of Pregnancy. [PDF]

, 2019
Maternal recognition of pregnancy (MRP) in the mare is not well defined. In a non-pregnant mare, prostaglandin F2α (PGF) is released on day 14 post-ovulation (PO) to cause luteal regression, resulting in loss of progesterone production. Equine MRP occurs
Bouma, Gerrit J, Bruemmer, Jason E, Cameron, Ashley D, Canovas, Angela, Coleman, Stephen J, Hess, Ann M, Islas-Trejo, Alma D, Kalbfleisch, Ted, Klohonatz, Kristin M, Medrano, Juan F, Reed, Kailee J   +10 more
core   +1 more source

A pilot study and case reports on endometrial microbiota and pregnancy outcome: An analysis using 16S rRNA gene sequencing among IVF patients, and trial therapeutic intervention for dysbiotic endometrium

Reproductive Medicine and Biology, 2018
The present study aimed to analyze the pregnancy outcomes of IVF patients presenting Lactobacillus‐dominated microbiota (LDM) or non‐Lactobacillus‐dominated microbiota (NLDM) of their endometrium and to report cases who were treated for NLDM concurrently
K. Kyono, T. Hashimoto, Suguru Kikuchi, Y. Nagai, Y. Sakuraba   +4 more
semanticscholar   +1 more source

The Regulation of Trace Metal Elements in Cancer Ferroptosis

Advanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang, Yuanyuan Xue, Lei Chang, Xuena Zhu, Wenjun Liu, Tingbo Liang   +5 more
wiley   +1 more source

Fine-tuned adaptation of embryo-endometrium pairs at implantation revealed by transcriptome analyses in Bos taurus.

PLoS Biology, 2019
Interactions between embryo and endometrium at implantation are critical for the progression of pregnancy. These reciprocal actions involve exchange of paracrine signals that govern implantation and placentation.
Fernando H Biase, Isabelle Hue, Sarah E Dickinson, Florence Jaffrezic, Denis Laloe, Harris A Lewin, Olivier Sandra   +6 more
doaj   +1 more source

Does pretrigger echogenic endometrium in assisted reproductive technology cycles reflect raised serum progesterone level?

Journal of Human Reproductive Sciences, 2018
Background: Serum progesterone is the main hormone of the luteal phase. The hyperechoic pattern of the endometrium in the luteal phase is believed to be induced by raised serum progesterone.
Monna Pandurangi, N Sanjeeva Reddy, G Usha Rani, Hepzibha Kirubamani   +3 more
doaj   +1 more source