Results 141 to 150 of about 299,455 (330)

Bridging the Gap Between Human Toxicology and Ecotoxicology Under One Health Perspective by a Cross‐Species Adverse Outcome Pathway Network for Reproductive Toxicity

Environmental Toxicology and Chemistry, EarlyView.
Cross‐species extrapolation of adverse outcome pathway network on reproductive toxicity under the One Health perspective using new approach methodologies. AOP = adverse outcome pathway. Abstract Although ecotoxicological and toxicological risk assessments are performed separately from each other, recent efforts have been made in both disciplines to ...
Elizabeth Dufourcq Sekatcheff, Jaeseong Jeong, Jinhee Choi   +2 more
wiley   +1 more source

FASTKD1 and FASTKD4 have opposite effects on expression of specific mitochondrial RNAs, depending upon their endonuclease-like RAP domain [PDF]

, 2017
Erik Boehm, Sofia Zaganelli, Kinsey Maundrell, Alexis A. Jourdain, Stéphane Thore, Jean‐Claude Martinou   +5 more
openalex   +1 more source

Targeting MGAT4A‐Mediated N‐Glycosylation as a Therapeutic Strategy to Inhibit Glioblastoma Stem Cell Invasion

Exploration, EarlyView.
ABSTRACT Glioblastoma (GBM) is the most aggressive type of primary brain tumor, and its invasive properties contribute significantly to incomplete surgical resection and tumor recurrence. Despite extensive clinical efforts to mitigate GBM invasion, targeted therapies against GBM stem cells (GSCs), which drive invasion, remain incompletely understood ...
Rui Niu, Meichen Liu, Qingshan Yang, Jinlong Yin   +3 more
wiley   +1 more source

Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System

Cell, 2015
Bernd Zetsche, J. Gootenberg, Omar O. Abudayyeh, I. Slaymaker, K. Makarova, Patrick Essletzbichler, Sara Volz, J. Joung, J. Oost, A. Regev, E. Koonin, Feng Zhang   +11 more
semanticscholar   +1 more source

Natural Transformation of an Engineered Helicobacter pylori Strain Deficient in Type II Restriction Endonucleases [PDF]

, 2012
Xue‐Song Zhang, Martin J. Blaser
openalex   +1 more source

An Improved Transformation System for Molecular Biology Research in Peach Fruit

Future Postharvest and Food, EarlyView.
Schematic Diagram of Repeated Agrobacterium‐Mediated Transformation. A triple‐stage on‐tree Agrobacterium injection enables gene manipulation in peach with up to 32‐day expression, supporting efficient, nonheritable functional analysis without tissue culture.
Chunhong Li, Yijia Xia, Minghua Zhou, Fei Xiang, Wancheng Huang, Xuansheng Tan, Yanyu Zou, Kaituo Wang   +7 more
wiley   +1 more source

A cladistic analysis of phenotypic associations with haplotypes inferred from restriction endonuclease mapping and DNA sequence data. III. Cladogram estimation.

Genetics, 1992
Alan R. Templeton, K. Crandall, C. Sing
semanticscholar   +1 more source

Regulation of the MLH1–MLH3 endonuclease in meiosis

Nature, 2020
E. Cannavó, Aurore Sanchez, Roopesh Anand, Lepakshi Ranjha, Jannik Hugener, C. Adam, A. Acharya, Nicolas Weyland, Xavier Aran-Guiu, J. Charbonnier, E. Hoffmann, V. Borde, Joao Matos, Petr Cejka   +13 more
semanticscholar   +1 more source

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

Ibrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

Nuclease mechanism of the avian retrovirus pp32 endonuclease [PDF]

, 1986
Duane P. Grandgenett, Ajaykumar C. Vora, Ronald Swanstrom, John C. Olsen   +3 more
openalex   +1 more source