Results 41 to 50 of about 299,455 (330)

tRNA splicing [PDF]

, 1998
Introns interrupt the continuity of many eukaryal genes, and therefore their removal by splicing is a crucial step in gene expression. Interestingly, even within Eukarya there are at least four splicing mechanisms.
Abelson, John, Li, Hong, Trotta, Christopher R.   +2 more
core   +1 more source

Budding Yeast SLX4 Contributes to the Appropriate Distribution of Crossovers and Meiotic Double-Strand Break Formation on Bivalents During Meiosis

G3: Genes, Genomes, Genetics, 2016
The number and distribution of meiosis crossover (CO) events on each bivalent are strictly controlled by multiple mechanisms to assure proper chromosome segregation during the first meiotic division.
Mika Higashide, Miki Shinohara
doaj   +1 more source

Actin-Resistant DNase1L2 as a Potential Therapeutics for CF Lung Disease

Biomolecules, 2021
In cystic fibrosis (CF), the accumulation of viscous lung secretions rich in DNA and actin is a major cause of chronic inflammation and recurrent infections leading to airway obstruction.
Danila Delfino, Giulia Mori, Claudio Rivetti, Antonella Grigoletto, Gloria Bizzotto, Cristian Cavozzi, Marco Malatesta, Davide Cavazzini, Gianfranco Pasut, Riccardo Percudani   +9 more
doaj   +1 more source

A CRISPR-Cas9 sex-ratio distortion system for genetic control. [PDF]

, 2016
Genetic control aims to reduce the ability of insect pest populations to cause harm via the release of modified insects. One strategy is to bias the reproductive sex ratio towards males so that a population decreases in size or is eliminated altogether ...
Bernardini, F, Crisanti, A, Galizi, R, Hammond, A, Kyrou, K, Nolan, T, O'Loughlin, SM, Papathanos, PA, Taxiarchi, C, Windbichler, N   +9 more
core   +3 more sources

Structure of an archaeal PCNA1-PCNA2-FEN1 complex: elucidating PCNA subunit and client enzyme specificity. [PDF]

, 2006
The archaeal/eukaryotic proliferating cell nuclear antigen (PCNA) toroidal clamp interacts with a host of DNA modifying enzymes, providing a stable anchorage and enhancing their respective processivities.
Andrew S. Doré, Antony W. Oliver, Brunger, Bunting, CCP4, Chang, Chapados, Dalrymple, DeLano, Dianova, Dionne, Dionne, Emsley, Friedrich-Heineken, Gulbis, Helt, Hingorani, Hosfield, Kelman, Kong, Kontopidis, Krishna, Krokan, Laurence H. Pearl, Leslie, Mairi L. Kilkenny, Matsumiya, Matsumoto, Murante, Murshudov, Oyama, Parker, Parrilla-Castellar, Pearl, Roberts, S. Mark Roe, Sakurai, Sarah A. Jones, Shamoo, Shen, Smirnova, Stephen D. Bell, Storoni, Tom, Toueille, Tsuchimoto, Venclovas, Volkmer, Wang   +48 more
core   +4 more sources

Intra- and Interspecies Analyses of the Carcinoembryonic Antigen (CEA) Gene Family Reveal Independent Evolution in Primates and Rodents [PDF]

, 1989
Various rodent and primate DNAs exhibit a stronger intra- than interspecies cross-hybridization with probes derived from the N-terminal domain exons of human and rat carcinoembryonic antigen (CEA)-like genes.
Rudert, Fritz, Thompson, John A., Zimmermann, Wolfgang   +2 more
core   +1 more source

Noncanonical DNA Cleavage by BamHI Endonuclease in Laterally Confined DNA Monolayers Is a Step Function of DNA Density and Sequence

Molecules, 2022
Cleavage of DNA at noncanonical recognition sequences by restriction endonucleases (star activity) in bulk solution can be promoted by global experimental parameters, including enzyme or substrate concentration, temperature, pH, or buffer composition. To
Abimbola F. Adedeji Olulana, Dianne Choi, Vincent Inverso, Shiv K. Redhu, Marco Vidonis, Luca Crevatin, Allen W. Nicholson, Matteo Castronovo   +7 more
doaj   +1 more source

DNA polymerases required for repair of UV-induced damage in Saccharomyces cerevisiae [PDF]

, 1995
The ability of yeast DNA polymerase mutant strains to carry out repair synthesis after UV irradiation was studied by analysis of postirradiation molecular weight changes in cellular DNA.
Budd, Martin E., Campbell, Judith L.
core   +2 more sources

Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replication

PLoS Pathogens, 2017
Coronaviruses are of veterinary and medical importance and include highly pathogenic zoonotic viruses, such as SARS-CoV and MERS-CoV. They are known to efficiently evade early innate immune responses, manifesting in almost negligible expression of type-I
Eveline Kindler, C. Gil-Cruz, Julia Spanier, Yize Li, J. Wilhelm, H. Rabouw, Roland Züst, M. Hwang, P. V’kovski, H. Stalder, S. Marti, M. Habjan, L. Cervantes-Barragan, R. Elliot, Nadja Karl, Christina Gaughan, F. V. van Kuppeveld, R. Silverman, M. Keller, B. Ludewig, C. Bergmann, J. Ziebuhr, S. Weiss, U. Kalinke, V. Thiel   +24 more
semanticscholar   +1 more source

Pseudomonas aeruginosa gene PA4880 encodes a Dps-like protein with a Dps fold, bacterioferritin-type ferroxidase centers, and endonuclease activity

Frontiers in Molecular Biosciences
We report the biochemical, structural, and functional characterization of the protein coded by gene PA4880 in the P. aeruginosa PAO1 genome. The PA4880 gene had been annotated as coding a probable bacterioferritin.
Nimesha Rajapaksha, Huili Yao, Aisha Cook, Steve Seibold, Lijun Liu, Kevin P. Battaile, Leo Fontenot, Fabrizio Donnarumma, Scott Lovell, Mario Rivera   +9 more
doaj   +1 more source