Results 161 to 170 of about 64,056 (293)

Rad1-Rad10 uses different interfaces to interact with pathway-specific DNA repair factors. [PDF]

Nucleic Acids Res
Rodríguez González J, Herman OT, Lewis KE, Matthews LA, Hess LD, Surtees JA, Guarné A.   +6 more
europepmc   +1 more source

A guide to transcriptional cyclin‐dependent kinases in cancer

The FEBS Journal, EarlyView.
Transcriptional cyclin‐dependent‐kinases (tCDKs) facilitate gene expression by promoting RNA polymerase II (RNAPII) progression through discrete phases of the transcription cycle. Aberrant tCDK activity is detectable in different human cancers, thereby contributing to de‐regulated gene expression programs that drive oncogenic phenotypes.
Jennifer R. Devlin, Salla Kyheröinen, Ricky W. Johnstone   +2 more
wiley   +1 more source

Genome Sequence of Mycobacteriophage Lilbit. [PDF]

MicroPubl Biol
Clavette E, Chuva A, Gruener N, Zinck J, Gusky S.   +4 more
europepmc   +1 more source

Gene Editing for Haemophilia—The Next Frontier

Haemophilia, EarlyView.
ABSTRACT The recently approved haemophilia A and B gene therapies via adeno‐associated virus (AAV) showed a promising therapeutic response after a single injection, but there are still limitations, including the potential loss of transgene expression and restriction in adults.
Mirko Pinotti, Gregory A. Newby, Sundar Selvaraj, Steven W. Pipe   +3 more
wiley   +1 more source

Recurrent Modular Assembly Drives Independent Origins of Group II Introns Encoding LAGLIDADG Homing Endonucleases. [PDF]

Genome Biol Evol
Liu F, Jin S, Du Q.
europepmc   +1 more source

From biology to biotechnology: Host‐regulation factors from parasitoid wasps are a source of bioactive molecules with translational potential

Insect Molecular Biology, EarlyView.
Parasitoid wasps deploy maternal and embryonic factors to reprogramme host physiology. Venom, calyx fluid, polydnaviruses, teratocytes and larval secretions act in a coordinated, compartmentalised manner. Host‐regulation factors are promising sources of insecticidal, antimicrobial and bioinspired translational molecules.
Ciro Pedro G. Pinto, Andrew A. Walker, Glenn F. King   +2 more
wiley   +1 more source

Mitochondrial genome characteristics and phylogenetic analysis of <i>Ramaria longispora</i>. [PDF]

Mitochondrial DNA B Resour
Yu Y, Liu C.
europepmc   +1 more source

ATXR5 and ATXR6 restrict meiotic crossover formation within heterochromatin in Arabidopsis

Journal of Integrative Plant Biology, EarlyView.
The Arabidopsis H3K27 mono‐methyltransferases ATXR5 and ATXR6 repress crossovers within meiotic heterochromatin, are required for heterochromatin condensation and H3K27me1 establishment, and specifically influence the maintenance of DNA methylation in meiocytes.
Jun Zhang, Yue Yu, Han Wang, Meiling Li, Dingning Li, Chenjiang You, Yingxiang Wang, Cong Wang   +7 more
wiley   +1 more source

Toxic Mechanism of Norfloxacin on <i>Chlamydomonas reinhardtii</i> by Triggering Programmed Cell Death. [PDF]

Plants (Basel)
Du X, Huang L, Lai M, Xu H, Huang T, Hu R, Ma J, Wei Y, Zuo Z.   +8 more
europepmc   +1 more source

α‐1,3‐Glucan Is Required for Cell Wall Integrity and Full Virulence of Colletotrichum graminicola, but Not for Evasion of PAMP‐Triggered Immunity

Molecular Microbiology, EarlyView.
Abbreviated Summary The role of the major fungal cell wall polymer α‐1,3‐glucan in plant infection is poorly understood. Deletion mutants of the maize anthracnose fungus Colletotrichum graminicola lacking all three α‐1,3‐glucan synthase genes differentiated severely distorted biotrophic hyphae in planta, and virulence was strongly reduced.
Iris Gase, Lala Aliyeva‐Schnorr, Michael Melzer, Maria Ott, Julia Haufe, Matthias Menzel, Timo Engelsdorf, Christiane Rohrbach, Alan de Oliveira Silva, Lars M. Voll, Alexander S. Mickel, Maximilian Groß, Mamoru Wakayama, Holger B. Deising   +13 more
wiley   +1 more source