Results 201 to 210 of about 64,056 (293)

A short history of Auto‐Rickshaw

Acta Crystallographica Section D, Volume 82, Issue 10, Page 1139-1151, October 2026.
Auto‐Rickshaw is an example of practical, decision‐driven automated macromolecular structure determination from crystallographic diffraction data. This review traces its development at the EMBL Hamburg/DESY beamline environment, where rapid validation of diffraction experiments was essential, through its expansion into a general platform for automated ...
Santosh Panjikar, Victor Lamzin, Paul A. Tucker, Manfred S. Weiss   +3 more
wiley   +1 more source

Molecular Characterization of a Restriction Endonuclease PsaI from <i>Pseudomonas anguilliseptica</i> KM9 and Sequence Analysis of the PsaI R-M System. [PDF]

Int J Mol Sci
Furmanek-Blaszk B, Mruk I, Sektas M.
europepmc   +1 more source

Perspectives for pharmaceutical screening at XFEL sources using the example of Lassa virus endonuclease

Acta Crystallographica Section D, Volume 82, Issue 10, Page 1181-1194, October 2026.
To facilitate structure‐based drug development, XFEL sources are of paramount interest. Here, we analyse the feasibility and data quality of serial femtosecond X‐ray crystallography compound screening at Linac Coherent Light Source and compare it with PETRA III synchrotron experiments.
Sven Falke, Patrick Y. A. Reinke, Daniel Rosenberg, Pontus Fischer, Jan Meyer, Marina Galchenkova, Alexandra Tolstikova, Valerio Mariani, Johanna M. Senst, Philipp Lewe, Susanne Witt, Armin Wagner, Henry N. Chapman, Mark Hunter, Sebastian Günther, Alke Meents   +15 more
wiley   +1 more source

Homogeneous Antibody-DNA Conjugates Using Unmodified Oligonucleotides and Photo-Cross-Linkable Protein G-HUH Endonuclease Fusion Proteins. [PDF]

Bioconjug Chem
Swietlikowska A, Hesen F, Gräwe A, Merkx M.   +3 more
europepmc   +1 more source

Genomic and Phenotypic Classification of Staphylococcus Species Isolated From Delhi Air

Environmental Microbiology Reports, Volume 18, Issue 5, October 2026.
Multiple Staphylococcus spp. were isolated from the outdoor polluted air of the Indian Capital, New Delhi. The bacterial samples were collected from 6 different locations, and the whole genome of four Staphylococcus isolates was sequenced in their entirety. This study presents the comparative genomic analysis of these four isolates.
Himanshu Sen, Joyasree Das, Suman Paul, Manpreet Kaur, Amareshwar Vodapalli, Surajit Bhattacharjee, Manoj Raje, Srinivasan Krishnamurthi, Saumya Raychaudhuri   +8 more
wiley   +1 more source

KU80 suppresses endonuclease G activity to preserve genomic integrity

The FEBS Journal, Volume 293, Issue 19, Page 5952-5966, October 2026.
Under normal conditions, EndoG remains restricted to mitochondria and the genome remains intact. When KU80 is absent, EndoG translocates into the nucleus, where it promotes DNA fragmentation and genomic instability. Thus, this work highlights the importance of KU80 in tightly controlling EndoG localization to preserve genome stability.
Jargalan Batsaikhan, Kwang‐Hyun Park, Hae Ryung Chang, Eunyoung Jung, Myung‐Jin Kim, Jeeyoon Kang, Hyunjo Shim, Eui‐Jeon Woo, Yonghwan Kim   +8 more
wiley   +1 more source

Development of a Microdroplet-Based Functional Genomic Screening Pipeline by Combination of DNA Nanoflowers and PURExpress Cell-Free Expression. [PDF]

ACS Synth Biol
Castells-Ballester J, Taron A, Smith M, Gawron R, Beaulieu J, Papa O, Buss J, Ong J, Chen M.   +8 more
europepmc   +1 more source

Transcriptomic and proteomic signatures underlying nymphal adaptation and foam production in the forage pest Mahanarva spectabilis

Insect Molecular Biology, Volume 35, Issue 5, Page 556-575, October 2026.
RNA‐seq and Batelli gland proteomics of fifth‐instar Mahanarva spectabilis nymphs reveal transcripts and proteins associated with xylem feeding, foam production and environmental interaction. Functional annotation identified genes involved in osmoregulation, detoxification, chemosensation and stress responses, while proteomic analysis confirmed ...
Monique da Silva Bonjour, Angelo José Rinaldi, Eulálio Gutemberg Dias dos Santos, Gabriely Teixeira Bhering Faria, Ana Márcia Escocard de Azevedo Manhães, Jorge Fernando Pereira, Alexander Machado Auad, Maria Goreti de Almeida Oliveira, Humberto Josué de Oliveira Ramos   +8 more
wiley   +1 more source

Naturally-occurring DNA fragment termini correlate with methylation at CpG sites in hair and blood plasma cell-free DNA. [PDF]

BMC Genomics
Sacco S, Kapp JD, Nguyen R, Rao IS, Green RE.   +4 more
europepmc   +1 more source

Estrogen/Esr2b signaling‐dependent, female‐biased expression of a neuropeptide Y gene in the medaka brain

Journal of Neuroendocrinology, Volume 38, Issue 10, October 2026.
Abstract A recent study showed that female medaka lacking the estrogen receptor gene esr2b are unreceptive to male courtship and instead court other females. In this study, we investigated the brain transcriptome of esr2b‐deficient females to explore the underlying mechanisms of this behavioral phenotype, and identified npyb, one of the two ...
Yuki Homan, Yuji Nishiike, Mika Sato‐Tsukamoto, Daisuke Saito, Mikita Suyama, Yasuyuki Ohkawa, Fumiya Takahashi, Takashi Baba, Ken‐ichirou Morohashi, Kataaki Okubo   +9 more
wiley   +1 more source