Results 201 to 210 of about 177,764 (316)

Mass spectrometry in ocular drug research

open access: yesMass Spectrometry Reviews, Volume 45, Issue 1, Page 37-68, January/February 2026.
Abstract Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research allowing analyzes from small samples and low concentrations. This review begins with a short introduction to eye physiology and ocular pharmacokinetics and the relevance of advancing ophthalmic treatments.
Eva M. del Amo   +6 more
wiley   +1 more source

Microfluidic Nanobiosensor Detection of Botulinum Neurotoxin Serotype A. [PDF]

open access: yesACS Omega
Srinivasan S   +6 more
europepmc   +1 more source

Hydrogen‐deuterium exchange reveals catalytically linked protein flexibility in myoglobin‐mediated intramolecular C(sp3)‐H activation

open access: yesProtein Science, Volume 35, Issue 1, January 2026.
Abstract A comprehensive understanding of the biophysical parameters that dictate high catalytic efficiency in enzymes is essential for advancing both fundamental enzymology and its applications. Experimental evidence suggests that protein dynamics play a pivotal role in transiently shaping active site configurations, facilitating the efficient ...
Hanzi Gao   +7 more
wiley   +1 more source

Novel prolyl endopeptidase inhibitor from <i>Myricaria germanica</i> alleviates steatohepatitis. [PDF]

open access: yesRSC Adv
Ullah K   +8 more
europepmc   +1 more source

Echinacoside Improves Pulmonary Vascular Remodeling by Regulating the L‐ and T‐Type Ca2+ Channels in the Prevention and Treatment of Pulmonary Hypertension

open access: yesPulmonary Circulation, Volume 16, Issue 1, January 2026.
ABSTRACT The typical pathology of pulmonary hypertension (PH) is characterized by pulmonary vasoconstriction and irreversible pulmonary vascular remodeling. Vascular remodeling is the process of structural changes and cellular rearrangement of blood vessels due to injury and is a significant factor in conditions such as PH.
Yuefu Zhao   +10 more
wiley   +1 more source

Targeted Therapy of Fungal Keratitis Enabled by Iron Nutritional Deprivation Combined With Photothermal Effect

open access: yesSmall Structures, Volume 7, Issue 1, January 2026.
This work developed a PDC nanoplatform that orchestrated a multimodal synergistic therapy, combining active targeting, photothermal therapy, and iron nutrient deprivation. The antifungal, anti‐inflammatory efficacy and corneal repair ability of nanoplatform were demonstrated through both in vitro and in vivo evaluations.
Ruojiao Feng   +13 more
wiley   +1 more source

Proteomic analysis of seminal plasma in Bali-polled bulls: Identifying biomarkers for fertility assessment. [PDF]

open access: yesJ Adv Vet Anim Res
Diansyah AM   +14 more
europepmc   +1 more source

Can prolyl endopeptidase reduce the IgE‐reactivity of gluten proteins? [PDF]

open access: gold, 2015
Frances J.D. Smith   +5 more
openalex   +1 more source

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