Results 91 to 100 of about 6,017 (150)

Endoplasmic reticulum aminopeptidases in the pathogenesis of ankylosing spondylitis: Fig. 1 [PDF]

Rheumatology, 2015
Tony J. Kenna, Philip C. Robinson, Nigil Haroon   +2 more
openaire   +1 more source

Endoplasmic reticulum aminopeptidase 2 regulates CD4+ T cells pyroptosis in rheumatoid arthritis

Arthritis Research & Therapy
Objective Rheumatoid arthritis (RA) is a chronic, progressive autoimmune disease with a complex pathogenesis that has not yet been fully elucidated, and T-cell pyroptosis is an important pathogenetic factor in RA. This study aimed to investigate the role
Jianhua Zhang, Hao Cai, Weiwei Sun, Weijie Wu, Yunyi Nan, Yingchen Ni, Xinyuan Wu, Minhao Chen, Hua Xu, Youhua Wang   +9 more
doaj   +1 more source

Identification of an Unconventional Subpeptidome Bound to the Behçet's Disease-associated HLA-B*51:01 that is Regulated by Endoplasmic Reticulum Aminopeptidase 1 (ERAP1). [PDF]

Mol Cell Proteomics, 2020
Chen L, Shi H, Koftori D, Sekine T, Nicastri A, Ternette N, Bowness P.   +6 more
europepmc   +1 more source

Combining ERAP1 silencing and entinostat therapy to overcome resistance to cancer immunotherapy in neuroblastoma

Journal of Experimental & Clinical Cancer Research
Background Checkpoint immunotherapy unleashes tumor control by T cells, but it is undermined in non-immunogenic tumors, e.g. with low MHC class I expression and low neoantigen burden, such as neuroblastoma (NB).
Patrizia Tempora, Silvia D’Amico, Paula Gragera, Verena Damiani, Kamila Krol, Valentina Scaldaferri, Kirti Pandey, Shanzou Chung, Valeria Lucarini, Ezio Giorda, Marco Scarsella, Gabriele Volpe, Marco Pezzullo, Cristiano De Stefanis, Valentina D’Oria, Lorenzo De Angelis, Roberto Giovannoni, Maria Antonietta De Ioris, Ombretta Melaiu, Anthony W. Purcell, Franco Locatelli, Doriana Fruci   +21 more
doaj   +1 more source

Sex-specific differences in endoplasmic reticulum aminopeptidase 1 modulation influence blood pressure and renin-angiotensin system responses. [PDF]

JCI Insight, 2019
Ranjit S, Wong JY, Wong JY, Tan JW, Sin Tay C, Lee JM, Yin Han Wong K, Pojoga LH, Brooks DL, Garza AE, Maris SA, Katayama IA, Williams JS, Rivera A, Adler GK, Williams GH, Romero JR.   +16 more
europepmc   +1 more source

Endoplasmic reticulum aminopeptidase 1 gene expression and serum angiotensin II levels associated with developing nephropathy in type2 diabetes patients. [PDF]

J Diabetes Metab Disord
Safdel S, Assadiasl S, Freidoon M, Mojtahedi H, Gheitasi M, Sadr M, Kazemzadehghadim H, Soleimanifar N, Nicknam MH.   +8 more
europepmc   +1 more source

High-Resolution Crystal Structure of Endoplasmic Reticulum Aminopeptidase 1 with Bound Phosphinic Transition-State Analogue Inhibitor. [PDF]

ACS Med Chem Lett, 2019
Giastas P, Neu M, Rowland P, Stratikos E.   +3 more
europepmc   +1 more source

Corrigendum: Endoplasmic Reticulum Associated Aminopeptidase 2 (ERAP2) Is Released in the Secretome of Activated MDMs and Reduces in vitro HIV-1 Infection

Frontiers in Immunology, 2019
Irma Saulle, Salomè Valentina Ibba, Enrica Torretta, Cecilia Vittori, Claudio Fenizia, Federica Piancone, Davide Minisci, Elisa Maria Lori, Daria Trabattoni, Cecilia Gelfi, Cecilia Gelfi, Mario Clerici, Mario Clerici, Mara Biasin   +13 more
doaj   +1 more source

Association of Endoplasmic Reticulum Aminopeptidase 1 Gene Polymorphism with Susceptibility and Severity of Axial Spondyloarthritis in Egyptian Population: A Single-center Case-Control Study. [PDF]

Ann Afr Med
Saad MA, Abdul-Sattar AB, Abdelal IT, Barak A.   +3 more
europepmc   +1 more source

The partial dissociation of MHC class I-bound peptides exposes their N terminus to trimming by endoplasmic reticulum aminopeptidase 1. [PDF]

J Biol Chem, 2018
Papakyriakou A, Reeves E, Beton M, Mikolajek H, Douglas L, Cooper G, Elliott T, Werner JM, James E.   +8 more
europepmc   +1 more source