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Neuroscience Letters, 2004
Acupuncture and electroacupuncture (EA) as complementary and alternative medicine have been accepted worldwide mainly for the treatment of acute and chronic pain. Studies on the mechanisms of action have revealed that endogenous opioid peptides in the central nervous system play an essential role in mediating the analgesic effect of EA. Further studies
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Endorphins and Pain

Psychiatric Clinics of North America, 1983
Endorphinergic neurons certainly play a role in the brain's processing of painful stimuli. Endorphins act to alter pain appreciation at many levels within the central nervous system including spinal cord, midbrain, thalamus, and cortex. The activity of this pain-suppressing system may play a role in individual differences in the experience of pain ...
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Radioimmunoassays for α-endorphin and β-endorphin

Biochemical and Biophysical Research Communications, 1977
Summary This note describes the technical details of double antibody radio-immunoassays for the two peptides α- and β-endorphin and the specificity characteristics of the antisera. Antisera raised in rabbits to synthetic α-endorphin measure quantitatively α-endorphin; usable range is 50 pg to 5 ng.
Roger Guillemin, Nicholas Ling, Therese Vargo +2 more
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Endorphins