Results 151 to 160 of about 29,952 (194)
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Annual Review of Psychology, 1982
INTRODUCTION 87 A NALGESIC EFFECTS 89 The Experimental Paradigm 89 Testing Analgesia 89 Tail .flick . . .. ... 89 Hot plate 90 Chemically induced pain 90 TRIGGERING THE ENDORPHINS 91 Shock-Induced Analgesia 91 Fear-Induced Analgesia .... .. 92 Unsettled Problems .
Robert C. Bolles, Michael S. Fanselow
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INTRODUCTION 87 A NALGESIC EFFECTS 89 The Experimental Paradigm 89 Testing Analgesia 89 Tail .flick . . .. ... 89 Hot plate 90 Chemically induced pain 90 TRIGGERING THE ENDORPHINS 91 Shock-Induced Analgesia 91 Fear-Induced Analgesia .... .. 92 Unsettled Problems .
Robert C. Bolles, Michael S. Fanselow
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1979
Publisher Summary This chapter discusses the identification and distribution of enkephalins and endorphins. The two main methods of detecting and quantitating enkephalins and endorphins used so far are radioimmunoassay and bioassay. In addition, opioid receptor binding assays were originally utilized to detect general opioid activity.
Richard J. Miller, Pedro Cuatrecasas
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Publisher Summary This chapter discusses the identification and distribution of enkephalins and endorphins. The two main methods of detecting and quantitating enkephalins and endorphins used so far are radioimmunoassay and bioassay. In addition, opioid receptor binding assays were originally utilized to detect general opioid activity.
Richard J. Miller, Pedro Cuatrecasas
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Radioimmunoassays for α-endorphin and β-endorphin
Biochemical and Biophysical Research Communications, 1977Summary This note describes the technical details of double antibody radio-immunoassays for the two peptides α- and β-endorphin and the specificity characteristics of the antisera. Antisera raised in rabbits to synthetic α-endorphin measure quantitatively α-endorphin; usable range is 50 pg to 5 ng.
Nicholas Ling +2 more
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Neuroscience Letters, 2004
Acupuncture and electroacupuncture (EA) as complementary and alternative medicine have been accepted worldwide mainly for the treatment of acute and chronic pain. Studies on the mechanisms of action have revealed that endogenous opioid peptides in the central nervous system play an essential role in mediating the analgesic effect of EA. Further studies
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Acupuncture and electroacupuncture (EA) as complementary and alternative medicine have been accepted worldwide mainly for the treatment of acute and chronic pain. Studies on the mechanisms of action have revealed that endogenous opioid peptides in the central nervous system play an essential role in mediating the analgesic effect of EA. Further studies
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Lymphocyte production of endorphins and endorphin-mediated immunoregulatory activity
The Journal of Immunology, 1985Abstract The immune and neuroendocrine systems appear able to communicate with each other by virtue of signal molecules (hormones) and receptors common to both systems. This review summarizes our data concerning the production of one type of neuroendocrine hormone, endorphins (END), by stimulated lymphocytes.
E M, Smith +2 more
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Psychiatric Clinics of North America, 1983
Endorphinergic neurons certainly play a role in the brain's processing of painful stimuli. Endorphins act to alter pain appreciation at many levels within the central nervous system including spinal cord, midbrain, thalamus, and cortex. The activity of this pain-suppressing system may play a role in individual differences in the experience of pain ...
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Endorphinergic neurons certainly play a role in the brain's processing of painful stimuli. Endorphins act to alter pain appreciation at many levels within the central nervous system including spinal cord, midbrain, thalamus, and cortex. The activity of this pain-suppressing system may play a role in individual differences in the experience of pain ...
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Human endorphin: Comparison with porcine endorphin, enkephalin and normorphine
Life Sciences, 1976Abstract We have extracted a material from human brain obtained at autopsy which has morphine-like activity on the mouse vas deferens preparation. This human endorphin behaved similarly on Sephadex G-15 and cation exchange columns as did porcine material and there were no qualitative differences in pharmacological activity between this material and ...
Edward L. Grinnan +4 more
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2016
β-END is an opioid peptide secreted from both corticotropes and melanotropes in the pars distalis and pars intermedia in the pituitary. β-END is substantially acetylated at the N-terminus in the pars intermedia. β-END peptides are generated from a precursor protein called proopiomelanocortin by posttranslational proteolytic cleavage.
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β-END is an opioid peptide secreted from both corticotropes and melanotropes in the pars distalis and pars intermedia in the pituitary. β-END is substantially acetylated at the N-terminus in the pars intermedia. β-END peptides are generated from a precursor protein called proopiomelanocortin by posttranslational proteolytic cleavage.
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