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Respiratory control during hypoxia in newborn rabbits: implied action of endorphins.
Journal of applied physiology: respiratory, environmental and exercise physiology, 1981The mechanism of ventilatory depression during hypoxia in the neonate is unknown. Since endorphins depress ventilation and their actions are antagonized by naloxone, we tested the effect of naloxone on respiration during acute hypoxia in newborn rabbits.
M. Grunstein, T. Hazinski, M. Schlueter
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Human endorphin: Comparison with porcine endorphin, enkephalin and normorphine
Life Sciences, 1976Abstract We have extracted a material from human brain obtained at autopsy which has morphine-like activity on the mouse vas deferens preparation. This human endorphin behaved similarly on Sephadex G-15 and cation exchange columns as did porcine material and there were no qualitative differences in pharmacological activity between this material and ...
Edward L. Grinnan +4 more
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Journal of Infectious Diseases, 1980
The specific opiate-antagonist naloxone rapidly reverses hypotension caused by endotoxin, hypovolemia, and spinal transection. In endotoxin shock in rats, naloxone's effects were stereospecific and were observed with intravenous (iv) doses as low as 0.1 ...
Alan I. Faden, J. Holaday
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The specific opiate-antagonist naloxone rapidly reverses hypotension caused by endotoxin, hypovolemia, and spinal transection. In endotoxin shock in rats, naloxone's effects were stereospecific and were observed with intravenous (iv) doses as low as 0.1 ...
Alan I. Faden, J. Holaday
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2016
β-END is an opioid peptide secreted from both corticotropes and melanotropes in the pars distalis and pars intermedia in the pituitary. β-END is substantially acetylated at the N-terminus in the pars intermedia. β-END peptides are generated from a precursor protein called proopiomelanocortin by posttranslational proteolytic cleavage.
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β-END is an opioid peptide secreted from both corticotropes and melanotropes in the pars distalis and pars intermedia in the pituitary. β-END is substantially acetylated at the N-terminus in the pars intermedia. β-END peptides are generated from a precursor protein called proopiomelanocortin by posttranslational proteolytic cleavage.
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Chapter 29 Endorphins and schizophrenia
1992Endorphins are produced in brain neurons, and as neuropeptides, they play a role as neuromessengers in the regulation of endocrine, autonomic, and behavioral functions. This chapter describes three hypotheses concerning a role of endorphins in schizophrenia: the endorphin-excess hypothesis, the γ-type endorphin hypotheses focus, and the fundamental and
Eric Ronken +3 more
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Archives of General Psychiatry, 1980
To study the effects of beta-endorphin in chronic schizophrenia, nine male patients participated in a double-blind crossover comparison of a single intravenous 20-mg injection of beta-endorphin and saline. Bolus injection of beta-endorphin from an albumin-coated syringe produced markedly higher plasma concentrations than did slow intravenous infusion ...
Choh Hao Li +8 more
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To study the effects of beta-endorphin in chronic schizophrenia, nine male patients participated in a double-blind crossover comparison of a single intravenous 20-mg injection of beta-endorphin and saline. Bolus injection of beta-endorphin from an albumin-coated syringe produced markedly higher plasma concentrations than did slow intravenous infusion ...
Choh Hao Li +8 more
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Response of plasma endorphins to running exercises in male and female endurance athletes.
Medicine & Science in Sports & Exercise, 1987We studied the responses of plasma concentrations of beta-endorphin, beta-lipotropin, and corticotropin to an exhaustive graded treadmill exercise, to an anaerobic treadmill exercise, and to a sub-maximal outdoor running exercise in 5 male and in 5 ...
P. Rahkila +3 more
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Endocrinology, 1979
Intravenous administration of the opiate receptor antagonist naloxone produced a significant reduction in basal serum PRL concentrations in four male Macaca arctoides.
M. S. Gold, D. Redmond, R. Donabedian
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Intravenous administration of the opiate receptor antagonist naloxone produced a significant reduction in basal serum PRL concentrations in four male Macaca arctoides.
M. S. Gold, D. Redmond, R. Donabedian
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Endorphins, opiates, and behavioural processes
, 1990Overview of the Endogenous Opioid Systems: Anatomical, Biochemical and Functional Issues Physiological Dependence on Opioids Opioid Reinforcement Processes Tolerance, Endorphins and Other Aspects of Opiate Drug Discrimination Environmentally-Induced ...
R. Rodgers, S. Cooper
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ALTERED PAIN PERCEPTION AND CEREBROSPINAL ENDORPHINS IN PSYCHIATRIC ILLNESS
Annals of the New York Academy of Sciences, 1982Clinical descriptions of insensitivity to pain among patients with schizophrenia have been reported for centuries. Similarly, patients with affective illness have been reported to experience pain differently in affective episodes than they do in well ...
G. Davis +6 more
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