Results 61 to 70 of about 16,934 (220)

Living at genetic risk: The patient experience of Lynch syndrome

International Journal of Cancer, EarlyView.
Abstract Lynch syndrome is a germline cancer predisposition syndrome caused by a variant in one of four genes. Lynch syndrome places individuals at significantly higher risk for a range of cancers, especially colorectal and endometrial. Depending on which gene is affected, the risk of ovarian, gastric, small bowel, pancreatic, biliary urothelial, brain,
Nicola Reents, Georgina Hoffmann, Kelly Kohut   +2 more
wiley   +1 more source

A multilevel perspective on MSH6‐associated Lynch syndrome: Integrating molecular, biological, and clinical insights

International Journal of Cancer, EarlyView.
Abstract Lynch syndrome (LS) is the most common hereditary colorectal cancer syndrome, caused by a germline pathogenic variant in one of the mismatch repair (MMR) genes. Among these, MSH6‐associated LS represents a distinct subtype with unique molecular and clinical characteristics.
Salwa Ben Yahia, Anne‐Sophie van der Werf‐'t Lam, Madalina Cabuta, Maartje Nielsen, Noah C. Helderman   +4 more
wiley   +1 more source

Adherens junction protein expression is associated with poor response to neoadjuvant FLOT chemotherapy and pro‐inflammatory tumor microenvironment in esophageal adenocarcinoma

International Journal of Cancer, EarlyView.
What's New? Esophageal adenocarcinoma (EAC) is an aggressive cancer with poor survival and variable response to perioperative chemotherapy. Although histopathological features correlate with outcomes, the relationship specifically between adherens junction (AJ) protein expression and treatment response in EAC remains uncertain.
Bastian Grothey, Heike Löser, Tillmann Bedau, Wolfgang Schröder, Christiane J. Bruns, Thomas Zander, Max Krämer, Reinhard Büttner, Alexander Quaas   +8 more
wiley   +1 more source

Metroplasty before IVF in women with a T‐shaped uterus: A clinical challenge

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract A T‐shaped uterus is a uterine malformation, which can be either congenital or acquired, potentially impairing fertility and increasing the risk of miscarriage. Diagnosis primarily relies on three‐dimensional ultrasound and hysteroscopy. Hysteroscopic metroplasty is the standard surgical intervention aimed at restoring normal uterine anatomy ...
Fabio Barra, Irene Gazzo, Alessandro Favilli, Consuelo Russo, Giulia Monaco, Franco Alessandri, Sandro Gerli, Luis Alonso Pacheco, Caterina Exacoustos, Simone Ferrero   +9 more
wiley   +1 more source

Comparative Outcomes of Endoscopic Treatment for Symptomatic and Asymptomatic Common Bile Duct Stones in the Elderly: A Propensity Score‐Based Cohort Analysis

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Introduction Various guidelines recommend endoscopic stone removal for asymptomatic common bile duct stones (CBDS); however, previous studies have indicated that asymptomatic CBDS is associated with a higher incidence of post‐ERCP pancreatitis (PEP).
Kota Shimojo, Akinori Maruta, Keisuke Iwata, Yuhei Iwasa, Mitsuru Okuno, Kensaku Yoshida, Shinya Uemura, Tsuyoshi Mukai, Takuji Iwashita, Masahito Shimizu   +9 more
wiley   +1 more source

Critical Appraisal of Pancreaticogastrostomy After Pancreatoduodenectomy: Evolution, Evidence, and Future Prospects

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Pancreaticogastrostomy (PG) emerged as a reconstructive option after pancreaticoduodenectomy (PD) due to its reported lower incidence of postoperative pancreatic fistula (POPF), but its superiority over pancreaticojejunostomy (PJ) remains unclear.
Samuel Menezes, Isabella R. Buonopane, Luís Felipe Leite, Anelise Poluboiarinov Cappellaro, Marcos Belotto   +4 more
wiley   +1 more source

CAQ Corner: Immune‐mediated complications

, 2022
Liver Transplantation, EarlyView.
Mary Thomson, John R. Lake
wiley   +1 more source

Extraosseous Ewing's Sarcoma Mimicking a Retropharyngeal Abscess: A Rare Case

Eye &ENT Research, EarlyView.
Syed Zohaib Maroof Hussain, Priya Dhar, Madeleine Grand, Charles Hall, Declan Costello   +4 more
wiley   +1 more source

Surrogate measure of gut blood flow via superior mesenteric circulation on ultrasound in adults who underwent esophagectomy: A descriptive cohort study

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Background Early enteral nutrition is recommended for critically ill patients. However, feeding an ischemic gastrointestinal tract with enteral nutrition may lead to gut necrosis. Although gut tolerance of enteral nutrition is assessed by various symptoms, none of them provide conclusive evidence of gut ischemia. We investigated the blood flow
Tomonori Narita, Kazuhiko Fukatsu, Reo Inoue, Satoshi Murakoshi, Midori Noguchi, Nana Matsumoto, Shoh Yajima, Koichi Yagi, Yoshifumi Baba   +8 more
wiley   +1 more source

Colonoscopy is not mammography: Challenges of applying the Duty of Candor

Endoscopy International Open
Maddalena Menini, Cesare Hassan
doaj   +1 more source