Results 101 to 110 of about 14,946 (225)
Chinese Journal of Lung Cancer, 2009 Background and objective It has been proven that radiotherapy can induce tumor cells over expressing HIF-1. The aim of this work is to investigate the effect of endostatin and radiotherapy on human lung cancer cell line A549 and the impact of HIF-1 ...
Yanyan ZHANG +4 more
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Journal of the Formosan Medical Association, 2006 Vascular endothelial growth factor (VEGF) and endostatin are related to ischemic heart disease. This study investigated pericardial fluid and serum levels of VEGF and endostatin in patients with or without ischemic heart disease.
Jer-Young Liou, Pei-Liang Kuan
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携带Egr-1启动子和Endostatin基因的腺病毒穿梭质粒构建及鉴定
Zhongguo shiyan zhenduanxue, 2008 目的构建含辐射敏感启动子Egr-1和人内皮抑素（endostatin）基因的腺病毒穿梭质粒pshuttle-Egr1-Endostatin。方法利用RT-PCR方法从人胎肝中扩增出人endostatin cDNA序列,从T-Egr1质粒中扩增出Egr-1基因序列,并将它们连接到pMD19T质粒进行测序,利用基因重组技术构建含有辐射诱导启动子Egr-1的腺病毒穿梭质粒pshuttle-Egr1-Endostatin。结果经测序证实,获得的人endostatin基因和Egr ...
李艳博 +6 more
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Mediators of Inflammation, 2003 We investigated the serum concentration of endostatin in 84 patients with multiple myeloma (MM) and in 13 healthy controls. The level of measured anti-angiogenic agent was correlated with the phase and stage of the disease, and most importantly with ...
Halina Urbanska-Rys, Tadeusz Robak
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Gene therapy of liver cancer [PDF]
, 2006 The application of gene transfer technologies to the treatment of cancer has led to the development of new experimental approaches like gene directed enzyme/pro-drug therapy (GDEPT), inhibition of oncogenes and restoration of tumor-suppressor genes.
Hernandez-Alcoceba, R. (Rubén) +2 more
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The response of VEGF-stimulated endothelial cells to angiostatic molecules is substrate-dependent
BMC Cell Biology, 2005 Background The microenvironment surrounding cells can exert multiple effects on their biological responses. In particular the extracellular matrix surrounding cells can profoundly influence their behavior.
Polverini Peter J +5 more
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Effect of endostatin overexpression on angiotensin II-induced cardiac hypertrophy in rats
Chinese Medical Journal, 2019 . Background:. Endostatin, a biologically active fragment of collagen XVIII, has been observed in patients with ischemic heart disease. The aim of the present study was to investigate whether endostatin overexpression could attenuate cardiac hypertrophy ...
You-Jin Dai +3 more
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Critical Care, 2018 Background Acute kidney injury (AKI) is associated with high morbidity and mortality in surgical patients. Nonrecovery from AKI may increase mortality and early risk stratification seems key to improving clinical outcomes.
Hui-Miao Jia +8 more
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Study of Modern Control Methodologies Applied to Tumor Growth under Angiogenic Inhibition [PDF]
, 2014 Cancer treatment is one of the most important research fields of modern medicine. In the last decades, targeted molecular therapies showed pr osperous results. These treatments achieve tumor regression with limited side-effects. Mathem atical models
Angiogenic Inhibition +5 more
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Endostatin in the pancreas [PDF]
British Journal of Cancer, 2005 In this issue of the British Journal of Cancer, Brammer and co-workers investigate the status of endostatin expression in human pancreas cancer and normal pancreatic tissue. Endostatin was originally identified from the conditioned media of glioendothelioma cells as an inhibitor of angiogenesis (O'Reilly et al, 1997).
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