Results 81 to 90 of about 14,946 (225)

E-M, an Engineered Endostatin with High ATPase Activity, Inhibits the Recruitment and Alternative Activation of Macrophages in Non-small Cell Lung Cancer

Frontiers in Pharmacology, 2017
Endostatin recently was reported by our laboratory to possess ATPase activity that is indispensable for its anti-angiogenesis and anti-tumor effects. An engineered endostatin, E-M, which owns higher ATPase activity exhibits stronger inhibitory effects on
Min Xu, Min Xu, Min Xu, Shaosen Zhang, Shaosen Zhang, Shaosen Zhang, Lin Jia, Lin Jia, Lin Jia, Shan Wang, Shan Wang, Shan Wang, Jie Liu, Jie Liu, Jie Liu, Xuhui Ma, Xuhui Ma, Xuhui Ma, Chunying Wang, Chunying Wang, Chunying Wang, Yan Fu, Yan Fu, Yan Fu, Yongzhang Luo, Yongzhang Luo, Yongzhang Luo   +26 more
doaj   +1 more source

Effects of Recombinant Human Endostatin and Docetaxel on MMP and its Following Anti-neoplastic Effect under Different Administration Sequences [PDF]

, 2010
Background and objective The aim of this study is to observe the changes of MMP-2 and its regulators, and to investigate the mechanism of the two administration sequences of recombinant human endostatin (rh-endostatin) and docetaxel.
Jing YUAN, Kai LI
core  

Reciprocal interactions between tumor and endothelial cells: Effects of selective vasopressin V2 receptor peptide agonists [PDF]

, 2014
Recent experimental evidence suggested that the synthetic peptide desmopressin (DDAVP) interferes tumor angiogenesis by inducing the formation of angiostatin.
Alonso, Daniel Fernando, Garona, Juan
core   +1 more source

Biomarkers of Extracellular Matrix Remodelling Are Linked to Severity and Outcome of Advanced Chronic Liver Disease

Alimentary Pharmacology &Therapeutics, Volume 63, Issue 5, Page 648-661, March 2026.
Extracellular matrix (ECM) remodelling biomarkers reflect portal hypertension and disease severity in advanced chronic liver disease (ACLD). However, their predictive value for disease progression is largely restricted to compensated ACLD (cACLD). ABSTRACT Background Extracellular matrix (ECM) remodelling in advanced chronic liver disease (ACLD) is ...
Benedikt Simbrunner, Ida Falk Villesen, Georg Semmler, Lorenz Balcar, Georg Kramer, Joana Almeida Calvão, Benedikt Silvester Hofer, Mathias Jachs, Lukas Hartl, Jurij Maurer, Bernhard Scheiner, Kerstin Zinober, Rodrig Marculescu, Michael Trauner, Morten Karsdal, Thomas Reiberger, Mattias Mandorfer, Diana Julie Leeming   +17 more
wiley   +1 more source

Difference in Serum Endostatin Levels in Diabetic Patients with Critical Limb Ischemia Treated by Autologous Cell Therapy or Percutaneous Transluminal Angioplasty

Cell Transplantation, 2018
The aim of this study was to compare the serum levels of the anti-angiogenic factor endostatin (S-endostatin) as a potential marker of vasculogenesis after autologous cell therapy (ACT) versus percutaneous transluminal angioplasty (PTA) in diabetic ...
Andrea Nemcova, Alexandra Jirkovska, Michal Dubsky, Libor Kolesar, Robert Bem, Vladimira Fejfarova, Anna Pysna, Veronika Woskova, Jelena Skibova, Edward B. Jude   +9 more
doaj   +1 more source

Basement membrane proteoglycans: modulators Par Excellence of cancer growth and angiogenesis. [PDF]

, 2009
Proteoglycans located in basement membranes, the nanostructures underling epithelial and endothelial layers, are unique in several respects. They are usually large, elongated molecules with a collage of domains that share structural and functional ...
Iozzo, Renato V, Nyström, Alexander, Zoeller, Jason J   +2 more
core   +2 more sources

Needling Therapy for Burn Injury and Related Complications: A Scoping Review of Experimental and Clinical Studies

International Wound Journal, Volume 23, Issue 2, February 2026.
ABSTRACT Needling therapy may be a novel alternative therapeutic intervention for burn injuries and related complications. This scoping review aimed to comprehensively evaluate the evidence status of needling therapy for burns and their complications. Studies on needling therapy for burns and related complications were retrieved from inception to 1st ...
Sung‐A Kim, Jung Won Kang, Tae‐Hun Kim   +2 more
wiley   +1 more source

Effects of Rh-endostar in Combination with Radiotherapy on Rats with Lung Cancer [PDF]

, 2010
Background and objective Radiation sensitivity is closely related to tissue oxygen, and rh-endostatin can induce the high level of oxygen content in tumor by "normalizing" tumor angiogenesis which is associated with radiotherapy sensitivity.
Changhu LI, Du HE, Fang YANG, Wei GE, Ximin XU, Zhenyu ZHAO   +5 more
core  

Herbal compound "Songyou Yin" reinforced the ability of interferon-alfa to inhibit the enhanced metastatic potential induced by palliative resection of hepatocellular carcinoma in nude mice [PDF]

, 2010
Background Liver resection is a widely accepted treatment for hepatocellular carcinoma (HCC). Our previous clinical study showed that the rate of palliative resection was 34.0% (1958-2008, 2754 of 8107).
Xiu-Yan Huang, Zi-Li Huang, Lu Wang, Yong-Hua Xu, Xin-Yu Huang, Kai-Xing Ai, Qi Zheng, Zhao-You Tang   +7 more
core   +1 more source

Progressive Insights into 3D Bioprinting for Corneal Tissue Restoration

Advanced Healthcare Materials, Volume 15, Issue 3, 19 January 2026.
This review explores the potential of 3D bioprinting to replicate the complex structure and function of the human cornea. It highlights key advances in bioink development, printing modalities, and in vivo performance, while addressing current challenges and emerging strategies. The review emphasizes bioprinting's promise to overcome donor shortages and
Ilayda Namli, Deepak Gupta, Yogendra Pratap Singh, Pallab Datta, Muhammad Rizwan, Mehmet Baykara, Ibrahim T. Ozbolat   +6 more
wiley   +1 more source